2022
The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder
Weeland CJ, Kasprzak S, de Joode NT, Abe Y, Alonso P, Ameis SH, Anticevic A, Arnold PD, Balachander S, Banaj N, Bargallo N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brecke V, Brem S, Cappi C, Cheng Y, Cho KIK, Costa DLC, Dallaspezia S, Denys D, Eng GK, Ferreira S, Feusner JD, Fontaine M, Fouche JP, Grazioplene RG, Gruner P, He M, Hirano Y, Hoexter MQ, Huyser C, Hu H, Jaspers-Fayer F, Kathmann N, Kaufmann C, Kim M, Koch K, Bin Kwak Y, Kwon JS, Lazaro L, Li CR, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minnuzi L, Moreira PS, Morgado P, Nakagawa A, Nakamae T, Narayanaswamy JC, Nurmi EL, Ortiz AE, Pariente JC, Piacentini J, Picó-Pérez M, Piras F, Piras F, Pittenger C, Reddy YCJ, Rodriguez-Manrique D, Sakai Y, Shimizu E, Shivakumar V, Simpson HB, Soreni N, Soriano-Mas C, Sousa N, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Takahashi J, Tanamatis T, Tang J, Thorsen AL, Tolin D, van der Werf YD, van Marle H, van Wingen GA, Vecchio D, Venkatasubramanian G, Walitza S, Wang J, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zhao Q, White T, Thompson P, Stein D, van den Heuvel O, Vriend C. The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder. Translational Psychiatry 2022, 12: 70. PMID: 35190533, PMCID: PMC8861046, DOI: 10.1038/s41398-022-01823-2.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMagnetic resonance imagingThalamic volumeOCD patientsThalamic subregionsT1-weighted brain magnetic resonance imagingBrain magnetic resonance imagingClinical-level symptomsLarger thalamic volumesPediatric OCD patientsAdult OCD patientsSeparate multiple linear regression modelsVolumetric group differencesThalamus sizeMedicated patientsAdolescent patientsAnterior thalamusHealthy controlsSubregional volumesGeneral populationMedication statusMultiple comparison correctionPatientsResonance imagingIntracranial volume
2021
Characterizing neuroanatomic heterogeneity in people with and without ADHD based on subcortical brain volumes
Li T, van Rooij D, Mota N, Buitelaar J, Ambrosino S, Banaschewski T, Bandeira C, Bau C, Baumeister S, Baur‐Streubel R, Bellgrove M, Biederman J, Bralten J, Bramati I, Brandeis D, Berm S, Busatto G, Calvo A, Castellanos F, Cercignani M, Chantiluke K, Christakou A, Coghill D, Conzelmann A, Cubillo A, Cupertino R, de Zeeuw P, Durston S, Earl E, Epstein J, Ethofer T, Fallgatter A, Fair D, Faraone S, Frodl T, Gabel M, Gogberashvili T, Grevet E, Haavik J, Harrison N, Hartman C, Heslenfeld D, Hoekstra P, Høvik M, Jahanshad N, Kardatzki B, Karkashadze G, Kelly C, Kohls G, Konrad K, Kuntsi J, Lazaro L, Lera‐Miguel S, Lesch K, Louza M, Lundervold A, Malpas C, Mattos P, McCarthy H, Nicolau R, Nigg J, Tuura R, Oosterlaan J, Oranje B, Paloyelis Y, Pauli P, Picon F, Plessen K, Ramos‐Quiroga J, Reif A, Reneman L, Rosa P, Rubia K, Schrantee A, Schweren L, Seitz J, Shaw P, Silk T, Skokauskas N, Vila J, Soloveva A, Stevens M, Sudre G, Tamm L, Thompson P, Tovar‐Moll F, van Erp T, Vance A, Vilarroya O, Vives‐Gilabert Y, von Polier G, Walitza S, Yoncheva Y, Zanetti M, Ziegler G, Anikin A, Asherson P, Baranov A, Chaim‐Avanicini T, Dale A, Doyle A, Jernigan T, Hohmann S, Kapilushniy D, Mehta M, Namazova‐Baranova L, Novotny S, Weiss E, Schwarz L, Hoogman M, Vasquez A, Franke B. Characterizing neuroanatomic heterogeneity in people with and without ADHD based on subcortical brain volumes. Journal Of Child Psychology And Psychiatry 2021, 62: 1140-1149. PMID: 33786843, PMCID: PMC8403135, DOI: 10.1111/jcpp.13384.Peer-Reviewed Original Research
2016
Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis
Boedhoe PS, Schmaal L, Abe Y, Ameis SH, Arnold PD, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Calvo A, Cheng Y, Cho KI, Dallaspezia S, Denys D, Fitzgerald KD, Fouche JP, Giménez M, Gruner P, Hanna GL, Hibar DP, Hoexter MQ, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Koch K, Kwon JS, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Nakamae T, Nakao T, Narayanaswamy JC, Piras F, Piras F, Pittenger C, Reddy YC, Sato JR, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stevens MC, Szeszko PR, Tolin DF, Venkatasubramanian G, Walitza S, Wang Z, van Wingen GA, Xu J, Xu X, Yun JY, Zhao Q, Thompson P, Stein D, van den Heuvel O, Abe Y, Alonso P, Ameis S, Arnold P, Bargalló N, Batistuzzo M, Benedetti F, Beucke J, Boedhoe P, Bollettini I, Bose A, Brem S, Busatto G, Calvo A, Calvo R, Cath D, Cheng Y, Cho K, Dallaspezia S, de Vries F, de Wit S, Denys D, Fang Y, Fitzgerald K, Fontaine M, Fouche J, Giménez M, Gruner P, Hanna G, Hibar D, Hoexter M, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Khadka S, Koch K, Kwon J, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón J, Miguel E, Minuzzii L, Morer A, Nakamae T, Nakao T, Narayanaswamy J, Piras F, Piras F, Pittenger C, Reddy Y, Sato J, Simpson H, Schmaal L, Soreni N, Soriano-Mas C, Spalletta G, Stein D, Stevens M, Szeszko P, Thompson P, Tolin D, Veltman D, Venkatasubramanian G, van den Heuvel O, van der Werf Y, van Wingen G, Walitza S, Wang Z, Xu J, Xu X, Yun J, Zhao Q. Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis. American Journal Of Psychiatry 2016, 174: 60-69. PMID: 27609241, PMCID: PMC5344782, DOI: 10.1176/appi.ajp.2016.16020201.Peer-Reviewed Original ResearchConceptsAdult obsessive-compulsive disorderObsessive-compulsive disorderOCD patientsLarger thalamic volumesSubcortical volume alterationsSmaller hippocampal volumesAdult OCD patientsPediatric obsessive-compulsive disorderPotential modulating effectSubcortical brain volumesLimited statistical powerPallidum volumeClinical characteristicsAdult patientsPediatric patientsMean ageThalamic volumeControl subjectsPediatric controlsSubcortical abnormalitiesIllness profileHippocampal volumeHealthy subjectsNeurodevelopmental alterationsPatients
2014
Brain activity in predominantly-inattentive subtype attention-deficit/hyperactivity disorder during an auditory oddball attention task
Orinstein AJ, Stevens MC. Brain activity in predominantly-inattentive subtype attention-deficit/hyperactivity disorder during an auditory oddball attention task. Psychiatry Research 2014, 223: 121-128. PMID: 24953999, PMCID: PMC4120259, DOI: 10.1016/j.pscychresns.2014.05.012.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderAttention taskADHD subtypesHyperactivity disorderNovel stimuliBrain activityMemory-related cognitive processesPrevious functional neuroimaging studiesBilateral superior temporal gyrusRight posterior parietal cortexNumerous cognitive tasksFunctional neuroimaging studiesInfrequent target stimuliAge-matched control participantsSuperior temporal gyrusPosterior parietal cortexTemporal lobe structuresGreater hemodynamic activityAttentional orientingCognitive processesCognitive tasksTarget stimuliInattentive subtypeLateral temporal lobe structuresAttention deficits