2013
Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder
Balodis IM, Kober H, Worhunsky PD, White MA, Stevens MC, Pearlson GD, Sinha R, Grilo CM, Potenza MN. Monetary Reward Processing in Obese Individuals With and Without Binge Eating Disorder. Biological Psychiatry 2013, 73: 877-886. PMID: 23462319, PMCID: PMC3686098, DOI: 10.1016/j.biopsych.2013.01.014.Peer-Reviewed Original ResearchConceptsReward/loss processingReward processingLoss processingVentromedial prefrontal cortex activityFunctional magnetic resonance imagingMonetary reward processingPrefrontal cortex activityBinge Eating DisorderVentral striatal activityNeural differencesNeural correlatesLoss taskLoss prospectsNeurobiological underpinningsCortex activityEating DisordersRegional activationVentral striatumBED groupAnticipatory phaseStriatal activityProcessingIndividualsOB groupObese individuals
2012
Diminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling
Balodis IM, Kober H, Worhunsky PD, Stevens MC, Pearlson GD, Potenza MN. Diminished Frontostriatal Activity During Processing of Monetary Rewards and Losses in Pathological Gambling. Biological Psychiatry 2012, 71: 749-757. PMID: 22336565, PMCID: PMC3460522, DOI: 10.1016/j.biopsych.2012.01.006.Peer-Reviewed Original ResearchConceptsAlcohol dependencePathological gamblingVentral striatumMagnetic resonance imaging studyResonance imaging studyFunctional magnetic resonance imaging studyBrain activation changesMonetary incentive delay taskReward processingLoss processingPresent functional magnetic resonance imaging (fMRI) studyControl comparison groupIncentive delay taskVentral striatal activationPG groupMonetary rewardsVentromedial prefrontal cortexSimilar associationImaging studiesFrontostriatal activityLoss anticipationConsistent alterationsActivation changesPrefrontal cortexLevels of impulsivity