2013
Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition
Tolin DF, Witt ST, Stevens MC. Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Research 2013, 221: 142-148. PMID: 24389161, PMCID: PMC3946244, DOI: 10.1016/j.pscychresns.2013.11.009.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGo/NoGo taskFunctional magnetic resonance imagingOCD patientsHD patientsResponse inhibitionNoGo taskHealthy controlsGo/NoGo task performanceDistinct neural underpinningsRight orbitofrontal gyrusErrors of commissionNeural underpinningsOrbitofrontal activationTask performanceCorrect rejectsMagnetic resonance imagingHemodynamic activityFrontal hypoactivityNeural activityOrbitofrontal gyrusBehavioral dataHemodynamic responsePatientsPreliminary evidenceA large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task
Steele VR, Aharoni E, Munro GE, Calhoun VD, Nyalakanti P, Stevens MC, Pearlson G, Kiehl KA. A large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task. Behavioural Brain Research 2013, 256: 529-536. PMID: 23756137, PMCID: PMC4437665, DOI: 10.1016/j.bbr.2013.06.001.Peer-Reviewed Original ResearchConceptsSuccessful response inhibitionGo/NoGo taskResponse inhibitionUnsuccessful response inhibitionMagnetic resonance imaging studySupplementary motor areaResonance imaging studyFunctional magnetic resonance imaging studyInferior parietal lobuleNoGo taskInferior prefrontal regionsHealthy adult participantsBasal gangliaInferior frontal gyrusHemodynamic responseMotor areaAnterior cingulateImaging studiesParietal lobuleFronto-parietal networkHemodynamic activityFrontal gyrusFrontostriatal regionsSmall sample studiesPrefrontal regions
2012
fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching
Witt ST, Stevens MC. fMRI task parameters influence hemodynamic activity in regions implicated in mental set switching. NeuroImage 2012, 65: 139-151. PMID: 23079572, PMCID: PMC3523276, DOI: 10.1016/j.neuroimage.2012.09.072.Peer-Reviewed Original ResearchConceptsBrain regionsMagnetic resonance imaging studySecondary visual cortexResonance imaging studyFunctional magnetic resonance imaging studySensorimotor cortexFronto-parietal regionsAnterior prefrontal cortexAnterior cingulateVisual cortexImaging studiesFronto-parietal networkPrefrontal cortexHemodynamic activityCortexBrain activityComplex executive functionsStimulus complexityExecutive functionResponse complexityTrialsNon-switch trialsPrevious studiesNeural mechanisms of cognitive behavioral therapy response in Hoarding Disorder: A pilot study
Tolin D, Stevens M, Nave A, Villavicencio A, Morrison S. Neural mechanisms of cognitive behavioral therapy response in Hoarding Disorder: A pilot study. Journal Of Obsessive-Compulsive And Related Disorders 2012, 1: 180-188. DOI: 10.1016/j.jocrd.2012.04.001.Peer-Reviewed Original ResearchCognitive behavioral therapyMedial frontal gyrusFrontal gyrusHemodynamic activityManualized group cognitive behavioral therapyCognitive behavioral therapy responsePosterior cingulateFunctional magnetic resonance imaging (fMRI) taskGroup cognitive behavioral therapyRight superior temporal gyrusDecision-making taskInsula/putamenRight posterior hippocampusSuperior temporal gyrusHealthy control participantsParietal lobe regionsHippocampus/parahippocampusNeural functionHoarding DisorderNeural mechanismsBehavioral therapyTemporal gyrusPosterior hippocampusHC participantsLobe regions
2010
Functional Imaging of Cognitive Control During Acute Alcohol Intoxication
Anderson BM, Stevens MC, Meda SA, Jordan K, Calhoun VD, Pearlson GD. Functional Imaging of Cognitive Control During Acute Alcohol Intoxication. Alcohol Clinical And Experimental Research 2010, 35: 156-165. PMID: 20958334, PMCID: PMC3005103, DOI: 10.1111/j.1530-0277.2010.01332.x.Peer-Reviewed Original ResearchConceptsCognitive controlError processingBrain regionsAnterior cingulateFunctional magnetic resonance imaging (fMRI) taskFunctional MRILateral prefrontal cortexParietal brain regionsFalse alarm responsesBrain hemodynamic activityFalse alarm errorsParietal lobe regionsNeural basisBehavioral performancePrefrontal cortexFMRI analysisHemodynamic activityLobe regionsAcute alcohol intoxicationAlarm errorsAlcohol effectsReaction timeAlcohol intoxicationCingulateAlarm response
2007
An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder
Stevens MC, Pearlson GD, Kiehl KA. An fMRI Auditory Oddball Study of Combined-Subtype Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2007, 164: 1737-1749. PMID: 17974940, DOI: 10.1176/appi.ajp.2007.06050876.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdolescent BehaviorAttentionAttention Deficit Disorder with HyperactivityAuditory PerceptionBrainBrain MappingCerebral CortexChildCognition DisordersDiagnostic and Statistical Manual of Mental DisordersEvoked PotentialsHemodynamicsHumansMagnetic Resonance ImagingMaleMemory DisordersOrientationOxygenPsychiatric Status Rating ScalesPsychomotor PerformanceConceptsAttention deficit hyperactivity disorderEvent-related potentialsFunctional magnetic resonance imagingDeficit hyperactivity disorderBrain regionsHyperactivity disorderHemodynamic activityThree-stimulus auditory oddball taskP3 event-related potentialEvent-related fMRI dataProcessing of targetsAbnormal hemodynamic activityWorking Memory DeficitsSlower task performanceAuditory oddball taskNovel environmental stimuliCortical brain regionsAttentional orientingOrient attentionADHD participantsCognitive processesCognitive representationsOddball studiesNeurobiological theoriesOddball stimuliFunctional neural networks underlying response inhibition in adolescents and adults
Stevens MC, Kiehl KA, Pearlson GD, Calhoun VD. Functional neural networks underlying response inhibition in adolescents and adults. Behavioural Brain Research 2007, 181: 12-22. PMID: 17467816, PMCID: PMC2266817, DOI: 10.1016/j.bbr.2007.03.023.Peer-Reviewed Original ResearchConceptsResponse inhibition circuitsBehavioral performance changesBrain hemodynamic activityResponse inhibitionFronto-striatal regionsThalamic modulationThalamic connectivityAge-related differencesPremotor cortexHealthy adolescentsGo/No-Go taskNeural circuitsHemodynamic activityEffective connectivity analysisInhibition circuitAdultsFunctional neural networksResponse suppressionAdolescentsConnectivity analysisFirst descriptionInhibitionNetwork engagement
2005
fMRI in an oddball task: Effects of target‐to‐target interval
Stevens MC, Calhoun VD, Kiehl KA. fMRI in an oddball task: Effects of target‐to‐target interval. Psychophysiology 2005, 42: 636-642. PMID: 16364059, DOI: 10.1111/j.1469-8986.2005.00368.x.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEvent-related potentialsTarget stimuliOddball taskTarget intervalTask-relevant target stimuliP3 event-related potentialBilateral lateral prefrontal cortexTask-relevant stimuliTemporal-parietal junctionLateral prefrontal cortexAuditory oddball taskMemory templateNovel stimuliPrefrontal cortexHemodynamic activityAnterior cingulateNeural systemsStimuliPositive relationshipLarge sampleHealthy adultsNeuronal modulationEffect of targetMagnetic resonance imagingLow-dose estradiol alters brain activity
Stevens MC, Clark VP, Prestwood KM. Low-dose estradiol alters brain activity. Psychiatry Research 2005, 139: 199-217. PMID: 16084069, DOI: 10.1016/j.pscychresns.2005.04.004.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSustained attention taskAttention taskEvent-related functional magnetic resonance imagingThree-stimulus oddball taskTasks of learningAlters brain activityEstrogen replacement therapyCortical brain regionsOddball taskBehavioral performanceBrain activityPrefrontal cortexHemodynamic activityAnterior cingulateDose estrogen replacement therapyNeural activityParietal lobeBrain regionsBrain functionReplacement therapyTaskGroup participantsDouble-blind studyMotor cortexHemispheric differences in hemodynamics elicited by auditory oddball stimuli
Stevens MC, Calhoun VD, Kiehl KA. Hemispheric differences in hemodynamics elicited by auditory oddball stimuli. NeuroImage 2005, 26: 782-792. PMID: 15955488, PMCID: PMC2759643, DOI: 10.1016/j.neuroimage.2005.02.044.Peer-Reviewed Original ResearchConceptsNovel stimuliInfrequent targetsRight hemisphereHemispheric differencesGreater right hemisphere activationTask-relevant target stimuliAuditory oddball stimuliEvent-related fMRIParietal lobe activityRight hemisphere activationFrequent standard stimuliTask-irrelevant novel stimuliPrevious neuroimaging studiesHealthy adult participantsAttentional processesNovelty processingSalient stimuliTarget stimuliOddball stimuliOddball taskNeuroimaging studiesStandard stimuliInfrequent novelLeft hemisphereHemodynamic activity