2018
Treatment Options for Wilson Disease
Kelly C, Pericleous M, Schilsky M. Treatment Options for Wilson Disease. Clinical Gastroenterology 2018, 45-61. DOI: 10.1007/978-3-319-91527-2_3.Peer-Reviewed Original ResearchWilson's diseaseMedical therapyTreatment of WDAsymptomatic patientsLiver transplantationSymptomatic patientsZinc therapyTreatment optionsPhysical therapyPhysician preferenceCopper intakeTherapyDietary changesPatientsMaintenance phaseTreatmentDiseaseCopper chelatorTransplantationDiagnosisIntakeSymptomatologyChapter 19 Wilson Disease and Related Disorders
Schilsky M. Chapter 19 Wilson Disease and Related Disorders. 2018, 253-268. DOI: 10.1016/b978-0-323-47874-8.00019-5.Peer-Reviewed Original ResearchMedical therapyWilson's diseaseRegression of diseaseCentral nervous systemLiver transplantationLiver failureLiver injuryDisease progressionNervous systemRelated disordersThird decadeDiseaseGenetic disordersCopper metabolismTherapyDisordersSecond decadeCopper accumulationCirrhosisTransplantationInjuryDiagnosisLiverProgression
2015
Su1011 Should Liver Transplantation Be Reconsidered in Patients With Intrahepatic Cholangiocarcinoma? A Systematic Review and Meta-Regression Analysis of Epidemiologic Evidence
Njei B, Schilsky M, Ditah I, Taddei T. Su1011 Should Liver Transplantation Be Reconsidered in Patients With Intrahepatic Cholangiocarcinoma? A Systematic Review and Meta-Regression Analysis of Epidemiologic Evidence. Gastroenterology 2015, 148: s-1036. DOI: 10.1016/s0016-5085(15)33541-1.Peer-Reviewed Original Research
2014
Radiology in Transplant
Kim A, Schilsky M. Radiology in Transplant. Current Transplantation Reports 2014, 1: 238-245. DOI: 10.1007/s40472-014-0034-5.Peer-Reviewed Original ResearchMagnetic resonance imagingHepatocellular carcinomaLiver transplantationContrast-enhanced ultrasoundUse of CTNon-invasive diagnosisGraft fibrosisLocoregional treatmentTumor histologyNew imaging techniquesLesion characteristicsNetwork criteriaDonor candidatesLiver lesionsOrgan allocationOrgan procurementResonance imagingLiver imagingEarly detectionTransplantationFibrosisUltrasoundImaging techniquesImagingSteatosis
2010
Wilson’s Disease
Schilsky M, Mitchell K. Wilson’s Disease. Molecular Pathology Library 2010, 5: 655-663. DOI: 10.1007/978-1-4419-7107-4_43.Peer-Reviewed Original ResearchWilson's diseaseAcute hepatic necrosisFuture human studiesAutosomal recessive disorderLiver transplantationClinical findingsHepatic necrosisPathological changesFuture therapiesAnimal modelsHuman studiesHepatocyte transplantationMolecular pathogenesisUltrastructural evaluationLiver tissueDiseaseClinical methodsRecessive disorderTransplantationCopper metabolismPathogenesisTherapyGene therapyDisordersMolecular diagnostics
2009
ICU Management of Acute Liver Failure
Schilsky ML, Honiden S, Arnott L, Emre S. ICU Management of Acute Liver Failure. Clinics In Chest Medicine 2009, 30: 71-87. PMID: 19186281, DOI: 10.1016/j.ccm.2008.10.001.Peer-Reviewed Original ResearchConceptsAcute liver failureLiver failureTeam approachGood ICU careOrganized team approachAcute liver injurySurvival of patientsBetter patient outcomesEarly disease recognitionLiver transplantationICU careLiver injuryICU managementPatient outcomesCritical carePatient managementSupportive measuresPatientsCareDisease recognitionICUTransplantationFailurePathophysiologyInjury
1999
Inherited metabolic disease
Schilsky M. Inherited metabolic disease. Current Opinion In Gastroenterology 1999, 15: 200-207. PMID: 17023946, DOI: 10.1097/00001574-199905000-00004.Peer-Reviewed Original ResearchMetabolic diseasesCrigler-Najjar syndromeDonor hepatocytesMetabolic disordersGenetic hemochromatosisNew treatmentsHuman recipientsWilson's diseaseDiseaseBilirubin glucuronidationGene mutationsFunctional effectsTherapeutic capabilitiesTreatmentDisordersRespective gene productsPast yearTransplantationPathophysiologyMetal metabolismSyndromePathogenesisGlucuronidationHemochromatosisLiverWilson’s disease
Tavill A, Schilsky M. Wilson’s disease. Current Treatment Options In Gastroenterology 1999, 2: 68-71. PMID: 11096575, DOI: 10.1007/s11938-999-0021-6.Peer-Reviewed Original ResearchPharmacologic therapyWilson's diseaseOrthotopic liver transplantationFulminant hepatic failureLiver transplantationCompliant patientsPreventive therapyHepatic failureHepatic insufficiencyMedical therapyOrgan damageMaintenance treatmentTherapyPatientsDiseaseTransplantationPrognosisInsufficiencyDiagnosis
1994
Liver transplantation for Wilson's disease: Indications and outcome
Schilsky M, Scheinberg I, Sternlieb I. Liver transplantation for Wilson's disease: Indications and outcome. Hepatology 1994, 19: 583-587. PMID: 8119682, DOI: 10.1002/hep.1840190307.Peer-Reviewed Original ResearchConceptsOrthotopic liver transplantationLiver transplantationNeurological Wilson's diseaseHepatic insufficiencyWilson's diseaseFulminant hepatitisSevere hepatic insufficiencyManagement of patientsIntractable neurological diseasesNonfatal complicationsGastrointestinal hemorrhageVascular complicationsMedian survivalMedical therapyRetrospective reviewPsychiatric manifestationsStudy groupPsychiatric symptomsPatientsTransplantationNeurological diseasesInsufficiencyDiseaseTransplantHepatitis