2024
Venous Thromboembolism Prophylaxis in Pregnancy: Why are the U.S. and European Guidelines so Different? Recent Studies and Clinical Insights
Piacquadio M, Paidas M. Venous Thromboembolism Prophylaxis in Pregnancy: Why are the U.S. and European Guidelines so Different? Recent Studies and Clinical Insights. Current Obstetrics And Gynecology Reports 2024, 14: 3. DOI: 10.1007/s13669-024-00407-9.Peer-Reviewed Original ResearchLow-molecular-weight heparinVenous thromboembolism prophylaxisVenous thromboembolismObstetric patientsEuropean guidelinesPostpartum periodHospitalized obstetric patientsMolecular weight heparinMechanical VTE prophylaxisVTE risk stratificationRandomized controlled studyObstetric populationPregnant populationRisk stratificationThromboembolism prophylaxisVTE prophylaxisInstitutional protocolMechanical prophylaxisWeight heparinProphylaxisAnticoagulant agentsPregnancyPoor adherenceControlled studiesPatients
2023
Inherited and Acquired Thrombophilias
Abhari P, Paidas M. Inherited and Acquired Thrombophilias. 2023, 114-122. DOI: 10.1002/9781119636540.ch14.Peer-Reviewed Original ResearchThrombophilic conditionsTransient hypercoagulable stateCoagulation factor levelsContext of pregnancyAcquired ThrombophiliaAntifibrinolytic systemsNeonatal outcomesProthrombotic tendencyHypercoagulable stateHormonal changesClinical consequencesThrombotic conditionsFactor levelsPregnancyThrombophiliaMaternalDiagnosis
2021
594 SARS-CoV-2 in pregnancy, placental fetal vascular malperfusion and the effect on fetal heart rate tracings
Colon-Aponte C, Saad A, Ndubizu C, Galli J, Ahn H, Abhari P, Cruz N, Cohen M, Covarrubias A, Potter J, Spiliopoulos M, Jayakumar A, Burkett G, Pahwa S, Paidas M, Sfakianaki A. 594 SARS-CoV-2 in pregnancy, placental fetal vascular malperfusion and the effect on fetal heart rate tracings. American Journal Of Obstetrics And Gynecology 2021, 224: s374. PMCID: PMC7848511, DOI: 10.1016/j.ajog.2020.12.615.Peer-Reviewed Original Research
2020
Thromboembolism
Paidas M. Thromboembolism. 2020, 181-200. DOI: 10.1002/9781119635307.ch19.Peer-Reviewed Original ResearchDeep venous thrombosisVenous thromboembolismRisk of DVTRisk of VTETransient hypercoagulable stateLeft lower extremityPrimary diagnostic modalitySystemic coagulationThromboembolic eventsNonpregnant womenFetal risksHypercoagulable stateVenous thrombosisVenous ultrasoundHemostatic challengesPregnant womenVascular traumaRisk factorsLower extremitiesVascular stasisDiagnostic modalitiesHormonal changesColor DopplerFibrinolytic systemPregnancy
2019
Omics and coagulation disorders in pregnancy
Ornaghi S, Paidas M. Omics and coagulation disorders in pregnancy. 2019, 149-155. DOI: 10.1201/9781315201955-24.Peer-Reviewed Original ResearchFetal growth restrictionOmics technologiesPlacenta-mediated complicationsMaternal thromboembolismSpecific biological sampleCoagulation disordersMolecular basisBiochemical pathwaysRegistry-based studyMessenger RNADifferent clinical conditionsVascular biologyPlacental abruptionFetal lossGrowth restrictionRisk factorsClinical conditionsLarge cohortNonbiased mannerBiomarker developmentThromboembolismPreeclampsiaComplicationsPregnancyRelevant diseases
2018
Venous thromboembolic disease
Ball B, Paidas M. Venous thromboembolic disease. 2018, 355-363. DOI: 10.1002/9781119072980.ch34.Peer-Reviewed Original ResearchReproduction and its impact on health and disease
Ornaghi S, Paidas M. Reproduction and its impact on health and disease. 2018, 391-402. DOI: 10.1201/9781315382104-47.Peer-Reviewed Original ResearchCardiovascular diseaseReproductive healthCVD riskReproductive axisMajor CVD risk factorsFirst-trimester bleedingMaternal CVD riskPattern of menstruationCVD risk factorsCommon obstetric complicationWomen's reproductive healthSubclinical processHypertensive disordersObstetric complicationsRisk factorsChronic diseasesNumber of childrenDisease trajectoriesPreventive effortsPregnancyMental healthDiseaseWomenFuture riskRisk315: Hypertensive disorders of pregnancy and severe cardiovascular morbidity in the immediate postpartum period
Ackerman C, Platner M, Pettker C, Spatz E, Paidas M, Zu X, Campbell K, Chung S, Lipkind H. 315: Hypertensive disorders of pregnancy and severe cardiovascular morbidity in the immediate postpartum period. American Journal Of Obstetrics And Gynecology 2018, 218: s198-s199. DOI: 10.1016/j.ajog.2017.10.251.Peer-Reviewed Original Research
2016
Thrombophilia and Pregnancy
Hendrix P, Tinelli A, Malvasi A, Paidas M. Thrombophilia and Pregnancy. 2016, 287-313. DOI: 10.1007/978-3-319-31377-1_13.Peer-Reviewed Original ResearchAdverse pregnancy outcomesPregnancy outcomesHereditary thrombophiliaBest practice clinical guidelinesContinuum of pregnancyVenous thromboembolic eventsRecurrent fetal lossIntrauterine growth restrictionProthrombin gene mutationNatural anticoagulant protein SFactor V LeidenEfficacy of preventionFetal morbidityThromboembolic eventsAntiphospholipid syndromeMaternal riskPuerperal periodClinical guidelinesFetal lossGrowth restrictionTreatment paradigmV LeidenRisk associationThrombophiliaPregnancy
2014
Combined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy
Petersen J, Bergholt T, Nielsen A, Paidas M, Løkkegaard E. Combined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy. Thrombosis And Haemostasis 2014, 112 DOI: 10.1160/th-13-09-0797.Peer-Reviewed Original ResearchCombined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy
Petersen J, Bergholt T, Nielsen A, Paidas M, Løkkegaard E. Combined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy. Thrombosis And Haemostasis 2014, 112: 73-78. PMID: 24499991, DOI: 10.1160/th13-09-0797.Peer-Reviewed Original ResearchConceptsVenous thromboembolismHormonal contraceptivesIncidence ratiosFirst-time venous thromboembolismCrude incidence ratioCombined oral contraceptivesNationwide retrospective cohortConfirmed pregnanciesOral contraceptivesRetrospective cohortHormonal contraceptionPuerperal periodAbsolute riskWeeks postpartumDanish womenMAIN OUTCOMEThromboembolismPregnancyContraceptivesOne-yearUnique registryFirst yearRiskBirthRegistry
2013
OC-03 Oral contraception and risk of venous thromboembolism within the first year following pregnancy
Petersen J, Bergholt T, Nielsen A, Lidegaard Ø, Paidas M, Løkkegaard E. OC-03 Oral contraception and risk of venous thromboembolism within the first year following pregnancy. Thrombosis Research 2013, 131: s71. DOI: 10.1016/s0049-3848(13)70029-x.Peer-Reviewed Original Research
2010
Inherited Bleeding Disorders in Obstetrics
Hossain N, Paidas M. Inherited Bleeding Disorders in Obstetrics. 2010, 153-160. DOI: 10.1002/9781444328332.ch7.Peer-Reviewed Original ResearchHigh-risk obstetriciansSecondary postpartum hemorrhageMenstrual cycle abnormalitiesQuality of lifeNecessary surgical interventionReferral physiciansAbruptio placentaePostpartum hemorrhageSurgical interventionGynecological practiceRecurrent miscarriageObstetric practiceAppropriate diagnosisBleeding disorderGynecological perspectiveCycle abnormalitiesReproductive lifeDisordersEarly stagesClose liaisonMorbidityComplicationsHemorrhagePregnancyGynecologistsDisseminated Intravascular Coagulation
Hossain N, Paidas M. Disseminated Intravascular Coagulation. 2010, 182-194. DOI: 10.1002/9781444328332.ch10.Peer-Reviewed Original ResearchDisseminated intravascular coagulationIntravascular coagulationEndothelial damageBlood productsAmniotic fluid embolismTransfusion of bloodAbruptio placentaeObstetric patientsHemorrhagic shockSystemic activationPrimary disorderFluid balanceIntravascular thrombiCoagulation factorsMultidisciplinary approachPregnancyPatientsObstetricsCoagulationBloodDisordersCorrect useLaboratory assaysConsequences of consumptionCoagulopathyMaternal and Fetal Thrombocytopenia
Paidas M, Hossain N. Maternal and Fetal Thrombocytopenia. 2010, 41-66. DOI: 10.1002/9781444328332.ch4.Peer-Reviewed Original ResearchNeonatal alloimmune thrombocytopeniaFetal thrombocytopeniaNeonatal thrombocytopeniaMaternal thrombocytopeniaFetal plateletsAlloimmune thrombocytopeniaFetus/neonateContext of pregnancyFetal platelet functionPrompt recognitionIntracranial hemorrhagePlatelet countFuture pregnanciesForeign antigensPlatelet functionThrombocytopeniaPregnancyPregnancy stateGenetic disordersNeonatesAntigenPlatelets resultsAntibodiesDisordersMothersThrombophilias and Pregnancy
Rodger M, Paidas M, Tsen L, Douglas J. Thrombophilias and Pregnancy. 2010, 101-117. DOI: 10.1002/9781444323016.ch4.Peer-Reviewed Original Research
2009
Pulmonary embolism in pregnancy
Bourjeily G, Paidas M, Khalil H, Rosene-Montella K, Rodger M. Pulmonary embolism in pregnancy. The Lancet 2009, 375: 500-512. PMID: 19889451, DOI: 10.1016/s0140-6736(09)60996-x.Peer-Reviewed Original ResearchConceptsPulmonary embolismRisk of complicationsBest possible treatmentPotential adverse effectsAppropriate prophylaxisVenous thromboembolismRisk stratificationVenous stasisPregnant womenVascular damageVirchow's triadFetal teratogenicityMaternal mortalityPharmacological treatmentTherapeutic interventionsPregnancyPossible treatmentAccurate diagnosisDiagnostic testingRight populationAdverse effectsEmbolismMortalityPhysiological changesDiagnosisEffect of 2 Stitches Versus 1 Stitch on the Prevention of Preterm Birth in Women With Singleton Pregnancies who Undergo Cervical Cerclage
Woensdregt K, Norwitz E, Cackovic M, Paidas M, Illuzzi J. Effect of 2 Stitches Versus 1 Stitch on the Prevention of Preterm Birth in Women With Singleton Pregnancies who Undergo Cervical Cerclage. Obstetric Anesthesia Digest 2009, 29: 142-143. DOI: 10.1097/01.aoa.0000358412.63284.c5.Peer-Reviewed Original Research
2008
10: Hypertensive disorders in pregnancy, recurrence in a second pregnancy, and subsequent cardiovascular events
Lykke J, Langhoff-Roos J, Triche E, Funai E, Sibai B, Paidas M. 10: Hypertensive disorders in pregnancy, recurrence in a second pregnancy, and subsequent cardiovascular events. American Journal Of Obstetrics And Gynecology 2008, 199: s6. DOI: 10.1016/j.ajog.2008.09.037.Peer-Reviewed Original ResearchAntithrombotic Therapy and Pregnancy: Consensus Report and Recommendations for Prevention and Treatment of Venous Thromboembolism and Adverse Pregnancy Outcomes
Duhl A, Paidas M, Ural S, Branch W, Casele H, Cox-Gill J, Hamersley S, Hyers T, Katz V, Kuhlmann R, Nutescu E, Thorp J, Zehnder J. Antithrombotic Therapy and Pregnancy: Consensus Report and Recommendations for Prevention and Treatment of Venous Thromboembolism and Adverse Pregnancy Outcomes. Obstetric Anesthesia Digest 2008, 28: 137-138. DOI: 10.1097/01.aoa.0000326376.74250.dd.Peer-Reviewed Original Research