2013
Immune Regulation and Oxidative Stress Reduction by Preimplantation Factor following Syngeneic or Allogeneic Bone Marrow Transplantation
Shainer R, Azar Y, Almogi-Hazan O, Bringer R, Compton S, Paidas M, Barnea E, Or R. Immune Regulation and Oxidative Stress Reduction by Preimplantation Factor following Syngeneic or Allogeneic Bone Marrow Transplantation. Conference Papers In Science 2013, 2013: 1-8. DOI: 10.1155/2013/718031.Peer-Reviewed Original ResearchBone marrow transplantationMarrow transplantationImmune responseAllogeneic bone marrow transplantationSyngeneic bone marrow transplantationAllogenic bone marrow transplantationImmune regulatory effectsProinflammatory gene expressionINOS gene expressionOxidative stress reductionImmune restorationPreImplantation FactorHost diseaseColon inflammationTransplant acceptanceINOS expressionSystemic immunityImmune regulationGene expressionMurine modelHematological diseasesWeight recoveryTransplantationOxidative stressTransplant success
2012
PreImplantation Factor Reduces Graft-versus-Host Disease by Regulating Immune Response and Lowering Oxidative Stress (Murine Model)
Azar Y, Shainer R, Almogi-Hazan O, Bringer R, Compton SR, Paidas MJ, Barnea ER, Or R. PreImplantation Factor Reduces Graft-versus-Host Disease by Regulating Immune Response and Lowering Oxidative Stress (Murine Model). Transplantation And Cellular Therapy 2012, 19: 519-528. PMID: 23266739, DOI: 10.1016/j.bbmt.2012.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone Marrow TransplantationCell ProliferationDendritic CellsGraft vs Host DiseaseGraft vs Leukemia EffectImmune ToleranceInflammationInterferon-gammaInterleukin-17LiverMiceMice, Inbred BALB CMice, Inbred C57BLNitric Oxide Synthase Type IIOxidative StressPeptidesSkinSpleenSurvival AnalysisT-Lymphocytes, RegulatoryTransplantation, HomologousConceptsBone marrow transplantationBeneficial GVL effectPreImplantation FactorAcute GVHDGVL effectHost diseaseImmune responseInducible nitric oxide synthase (iNOS) expressionAllogeneic bone marrow transplantationNitric oxide synthase expressionOxidative stressIL-17 levelsIFN-γ levelsSystemic immune responsesOxide synthase expressionAntigen-presenting cellsMurine BMT modelT cell proliferationNitric oxide secretionDonor-recipient matchingChemokine gene expressionLipopolysaccharide-activated macrophagesAcute graftAllogeneic embryosBeneficial graft