2002
Steroids for acute spinal cord injury
Bracken M. Steroids for acute spinal cord injury. Cochrane Database Of Systematic Reviews 2002, cd001046. PMID: 12137616, DOI: 10.1002/14651858.cd001046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnti-Inflammatory AgentsHumansMethylprednisolone HemisuccinateNeuroprotective AgentsSpinal Cord InjuriesConceptsAcute spinal cord injurySpinal cord injuryHours of injuryCord injuryMethylprednisolone therapySteroid treatmentPharmacological therapyRandomized trialsRecent trialsNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyHigh-dose methylprednisolone steroid therapySpinal Cord Injury StudyMotor neurologic functionOnly pharmacological therapyNorth American trialsLumbar disc diseaseStart of treatmentMethylprednisolone sodium succinateCochrane Injuries GroupYears post injurySteroid therapyMaintenance infusionDose regimenInjury group
2001
High dose methylprednisolone must be given for 24 or 48 hours after acute spinal cord injury
Bracken M. High dose methylprednisolone must be given for 24 or 48 hours after acute spinal cord injury. The BMJ 2001, 322: 862. PMID: 11290648, PMCID: PMC1120025, DOI: 10.1136/bmj.322.7290.862/b.Commentaries, Editorials and LettersAnti-Inflammatory AgentsDrug Administration ScheduleHumansMethylprednisoloneSpinal Cord InjuriesTime Factors
2000
Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury
Bracken M, Aldrich E, Herr D, Hitchon P, Holford T, Marshall L, Nockels R, Pascale V, Shepard M, Sonntag V, Winn H, Young W. Clinical Measurement, Statistical Analysis, and Risk-Benefit: Controversies from Trials of Spinal Injury. Journal Of Trauma And Acute Care Surgery 2000, 48: 558-561. PMID: 10744306, DOI: 10.1097/00005373-200003000-00036.Commentaries, Editorials and LettersConceptsNational Acute Spinal Cord Injury StudyAcute Spinal Cord Injury StudyAcute spinal cord injurySpinal Cord Injury StudyClinical measurementsHigh-dose methylprednisoloneSecondary neuronal damageSpinal cord injuryRisk benefitNeuronal damageFunctional recoverySafety profileCord injuryPharmacologic agentsSpinal injuryInjury studiesInnovative therapiesTrialsStatistical analysisInjuryMulticenterMethylprednisoloneSeries of trialsTherapyPrevention