2021
Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults?
Gupta A, Joshi P, Bhattacharya G, Lehman M, Funaro M, Tampi DJ, Tampi RR. Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? International Psychogeriatrics 2021, 34: 889-903. PMID: 33757611, DOI: 10.1017/s1041610221000235.Peer-Reviewed Educational MaterialsConceptsTreatment of deliriumTotal knee arthroplastyTotal hip arthroplastyPostoperative deliriumUse of anticonvulsantsPerioperative useSpinal surgeryOlder adultsElective total knee arthroplastyElective total hip arthroplastyUse of gabapentinCochrane Central RegisterAnalysis of RCTsPerioperative gabapentinCentral RegisterKnee arthroplastyHip arthroplastyDeliriumCurrent evidenceGabapentinRCTsAnticonvulsantsSystematic reviewArthroplastyComprehensive search
2020
A systematic review of ketamine for the treatment of depression among older adults
Gupta A, Dhar R, Patadia P, Funaro M, Bhattacharya G, Farheen SA, Tampi RR. A systematic review of ketamine for the treatment of depression among older adults. International Psychogeriatrics 2020, 33: 179-191. PMID: 32600480, DOI: 10.1017/s1041610220000903.Peer-Reviewed Educational MaterialsConceptsUse of ketaminePrimary outcome measureTreatment of depressionOlder adultsAdverse effectsOutcome measuresMontgomery-Asberg Depression Rating Scale scoreDepression Rating Scale scoresBenefits of ketamineCognitive adverse effectsRating Scale scoresEsketamine groupPlacebo groupRemission rateIntranasal ketamineKetamine administrationMADRS scoresInclusion criteriaDepressive symptomsCurrent evidenceScale scoreDepression symptomsKetamineSystematic reviewNegative trialsSystematic review of benzodiazepines for anxiety disorders in late life.
Gupta A, Bhattacharya G, Farheen SA, Funaro M, Balasubramaniam M, Young J, Tampi DJ, Tampi RR. Systematic review of benzodiazepines for anxiety disorders in late life. Annals Of Clinical Psychiatry 2020, 32: 114-127. PMID: 32343283.Peer-Reviewed Educational MaterialsConceptsAnxiety disordersSystematic reviewOlder adultsTolerability of benzodiazepinesCochrane Central RegisterMild adverse effectsLater lifeEnglish-language articlesTreatment of anxietyLong-term useWeb of ScienceTolerability dataCentral RegisterControlled TrialsCochrane DatabaseOvid EmbaseLong-term benefitsOvid MEDLINEInclusion criteriaEligible articlesBenzodiazepinesDecreased anxietyStudy periodAdverse effectsTrials