2020
Relevance of Microvascular Flow Assessments in Critically Ill Neonates and Children: A Systematic Review.
Maitoza LA, Neeman E, Funaro M, Pierce RW. Relevance of Microvascular Flow Assessments in Critically Ill Neonates and Children: A Systematic Review. Pediatric Critical Care Medicine 2020, 21: 373-384. PMID: 31834246, PMCID: PMC10061570, DOI: 10.1097/pcc.0000000000002201.Peer-Reviewed Original ResearchConceptsIll childrenMicrovascular flowSystematic reviewMicrocirculatory dysfunctionIll neonatesMicrocirculatory changesBlood flowImpact of patientMicrovascular blood flowMicrocirculatory blood flowFull-text reviewWeb of ScienceMacrovascular functionPatients 0Critical illnessEffect of ageSuch patientsMedical managementPoor outcomeBirth weightMicrocirculatory variablesClinical endpointsInclusion criteriaNeonatesMacrocirculatory variables
2018
Tight junction structure, function, and assessment in the critically ill: a systematic review
Vermette D, Hu P, Canarie MF, Funaro M, Glover J, Pierce RW. Tight junction structure, function, and assessment in the critically ill: a systematic review. Intensive Care Medicine Experimental 2018, 6: 37. PMID: 30259344, PMCID: PMC6158145, DOI: 10.1186/s40635-018-0203-4.Peer-Reviewed Original ResearchCritical illnessSystematic reviewTight junctionsGut bacterial translocationMultiple organ failureFull-text reviewEndothelial tight junctionsEndothelial barrier integrityCritical disease statesTJ structureBacterial translocationCardiac failureClinical outcomesOrgan failurePulmonary edemaBarrier disruptionPROSPERO databaseResultsA totalBarrier dysfunctionPulmonary pathologyTherapeutic advancesCapillary leakInclusion criteriaGastrointestinal epitheliumTJ breakdown