2021
Weight gain in menopause: systematic review of adverse events in women treated with black cohosh
Naser B, Castelo-Branco C, Meden H, Minkin M, Rachoń D, Beer A, Pickartz S. Weight gain in menopause: systematic review of adverse events in women treated with black cohosh. Climacteric 2021, 25: 220-227. PMID: 34608830, DOI: 10.1080/13697137.2021.1973993.Peer-Reviewed Original ResearchConceptsAdverse eventsWeight gainSpontaneous adverse eventsBody fat compositionScientific evidencePopular treatment optionPostmenopausal womenMenopausal womenMenopausal symptomsTreatment optionsCase reportTreatment groupsSystematic reviewBlack cohoshFat compositionWeight changeWomenSignificant differencesFrequent problemPerimenopausalMenopauseReviewGroupSymptomsCases
2020
Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence
Castelo-Branco C, Gambacciani M, Cano A, Minkin M, Rachoń D, Ruan X, Beer A, Schnitker J, Henneicke-von Zepelin H, Pickartz S. Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence. Climacteric 2020, 24: 109-119. PMID: 33021111, DOI: 10.1080/13697137.2020.1820477.Peer-Reviewed Original ResearchConceptsClimacteric symptomsMenopausal symptomsBetter benefit-risk profileLow-dose transdermal estradiolICR/Evidence-based treatment optionsEstrogen-sensitive organsEstrogen-sensitive tissuesPsychological menopausal symptomsMinor adverse eventsBenefit-risk profileEvidence of hepatotoxicityGood safety profileStandardized mean differenceHormone-dependent diseasesSystematic literature searchTransdermal estradiolAdverse eventsGood tolerabilitySafety profileTreatment optionsSt. John's wortHerbal therapyHormone levelsClinical dataEffects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial
Black D, Minkin M, Graham S, Bernick B, Mirkin S. Effects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial. Menopause The Journal Of The North American Menopause Society 2020, 28: 32-39. PMID: 32932401, PMCID: PMC7769186, DOI: 10.1097/gme.0000000000001659.Peer-Reviewed Original ResearchConceptsE2/P4Diastolic blood pressureSystolic blood pressureBlood pressurePostmenopausal womenREPLENISH trialMonth 12Treatment-emergent adverse eventsWeight gainTwelve-month useHealthy postmenopausal womenSevere vasomotor symptomsBody mass indexAdverse eventsVasomotor symptomsMass indexEfficacy profileWomenBaselineHypertensionPlaceboUterusTrialsImportant changesPrevious findings
2019
The International Society for the Study of Women's Sexual Health Process of Care for the Identification of Sexual Concerns and Problems in Women
Parish S, Hahn S, Goldstein S, Giraldi A, Kingsberg S, Larkin L, Minkin M, Brown V, Christiansen K, Hartzell-Cushanick R, Kelly-Jones A, Rullo J, Sadovsky R, Faubion S. The International Society for the Study of Women's Sexual Health Process of Care for the Identification of Sexual Concerns and Problems in Women. Mayo Clinic Proceedings 2019, 94: 842-856. PMID: 30954288, DOI: 10.1016/j.mayocp.2019.01.009.Peer-Reviewed Original ResearchConceptsProcess of careFemale sexual dysfunctionSexual problemsSexual concernsSexual healthWomen's sexual healthPatient-centered communication skillsCaregivers of womenCommon sexual problemInternational expert panelInternational SocietySexual dysfunctionCommon disorderDistressing problemSexual painClinician expertiseSexual medicine specialistsMedicine specialistsClinical practicePatient needsClinical settingSexual medicineWomenExpert panelClinicians
2011
Suspected black cohosh hepatotoxicity
Naser B, Schnitker J, Minkin M, de Arriba S, Nolte K, Osmers R. Suspected black cohosh hepatotoxicity. Menopause The Journal Of The North American Menopause Society 2011, 18: 366-375. PMID: 21228727, DOI: 10.1097/gme.0b013e3181fcb2a6.Peer-Reviewed Original ResearchConceptsIsopropanolic black cohosh extractClinical trialsPostmenopausal womenLiver functionAlanine aminotransferaseAspartate aminotransferaseBlack cohoshPopular herbal treatmentPlacebo-controlled studyMonths of treatmentLiver function valuesStandardized mean differenceBlack cohosh extractMenopausal symptomsHerbal treatmentHepatotoxicity casesMean differenceAdverse effectsAminotransferaseTrialsWomenNonsignificant effectDescriptive statisticsMonthsΓ-glutamyltranspeptidase