2023
Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants
Moriyama M, Lucas C, Monteiro V, Initiative Y, Iwasaki A, Chen N, Breban M, Hahn A, Pham K, Koch T, Chaguza C, Tikhonova I, Castaldi C, Mane S, De Kumar B, Ferguson D, Kerantzas N, Peaper D, Landry M, Schulz W, Vogels C, Grubaugh N. Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2221652120. PMID: 37036977, PMCID: PMC10120007, DOI: 10.1073/pnas.2221652120.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, NeutralizingAntibodies, ViralBreakthrough InfectionsCOVID-19HumansReinfectionSARS-CoV-2Spike Glycoprotein, CoronavirusConceptsMHC-I expressionBreakthrough infectionsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variantsMajor histocompatibility complex class I expressionCell-mediated immunityInfluenza virus infectionSARS-CoV-2 VOCsMHC-I upregulationClass I expressionSARS-CoV-2T cell recognitionVirus infectionMHC II expressionSpike proteinEnhanced inhibitionInfectionCell recognitionCommon mutationsReinfectionE proteinAntibodiesViral genesSubvariantsExpression
2020
Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients
Gaston DC, Malinis M, Osborn R, Peaper DR, Landry M, Juthani-Mehta M, Azar MM. Clinical implications of SARS-CoV-2 cycle threshold values in solid organ transplant recipients. American Journal Of Transplantation 2020, 21: 1304-1311. PMID: 33043603, PMCID: PMC7675520, DOI: 10.1111/ajt.16357.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsOrgan transplant recipientsClinical implicationsCycle threshold valuesSOT patientsTransplant recipientsSymptom onsetYale New Haven Health SystemUpper respiratory tract samplesSARS-CoV-2 viral RNASARS-CoV-2 viral dynamicsAdult SOT recipientsRetrospective chart reviewRespiratory tract samplesSARS-CoV-2 cycle threshold valuesInfection prevention measuresCOVID-19 severityViral RNAHigher clinical acuityPrimary diagnostic testRT-PCR assaysSOT recipientsChart reviewViral loadAdmission severityClosing the Brief Case: Secondary Measles and the Pitfalls of Diagnostic Testing
Azar MM, Canterino J, Landry ML. Closing the Brief Case: Secondary Measles and the Pitfalls of Diagnostic Testing. Journal Of Clinical Microbiology 2020, 58: 10.1128/jcm.01939-19. PMID: 32839285, PMCID: PMC7448644, DOI: 10.1128/jcm.01939-19.Peer-Reviewed Case Reports and Technical NotesThe Brief Case: Secondary Measles and the Pitfalls of Diagnostic Testing
Azar MM, Canterino J, Landry ML. The Brief Case: Secondary Measles and the Pitfalls of Diagnostic Testing. Journal Of Clinical Microbiology 2020, 58: 10.1128/jcm.01938-19. PMID: 32839284, PMCID: PMC7448623, DOI: 10.1128/jcm.01938-19.Peer-Reviewed Original Research
2016
Parvovirus B19
Landry ML. Parvovirus B19. Microbiology Spectrum 2016, 4: 10.1128/microbiolspec.dmih2-0008-2015. PMID: 27337440, DOI: 10.1128/microbiolspec.dmih2-0008-2015.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ViralDNA, ViralHumansImmunocompromised HostParvoviridae InfectionsParvovirus B19, HumanConceptsParvovirus B19 infectionIntravenous immunoglobulinB19 infectionIgG antibodiesImmune systemActive parvovirus B19 infectionPrimary parvovirus B19 infectionPure red cell aplasiaMaintenance intravenous immunoglobulinRed cell transfusionSufficient immune responsePatient's immune systemRed cell aplasiaReal-time polymerase chain reaction methodRed cell precursorsB19 variantsGiant pronormoblastsRecurrent anemiaB19 IgMChronic anemiaPolymerase chain reaction methodSevere anemiaTherapeutic optionsPrimary infectionParvovirus B19
2007
Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection
Bhaduri-McIntosh S, Landry ML, Nikiforow S, Rotenberg M, El-Guindy A, Miller G. Serum IgA Antibodies to Epstein-Barr Virus (EBV) Early Lytic Antigens Are Present in Primary EBV Infection. The Journal Of Infectious Diseases 2007, 195: 483-492. PMID: 17230407, DOI: 10.1086/510916.Peer-Reviewed Original ResearchConceptsPrimary EBV infectionSerum IgA antibodiesIgA antibodiesEBV infectionLytic antigensPrimary infectionPrimary Epstein-Barr virus infectionHealthy EBV-seropositive individualsEpstein-Barr virus infectionEB nuclear antigenEBV-seropositive individualsViral capsid antigenAbsence of antibodiesFlow cytometry-based assayLytic EBV replicationCytometry-based assayBurkitt's lymphoma cellsCapsid antigenMucosal sitesEBV replicationIgM antibodiesVirus infectionInfectionLymphoma cellsSerum samples
2005
Detection of Human Metapneumovirus in Clinical Samples by Immunofluorescence Staining of Shell Vial Centrifugation Cultures Prepared from Three Different Cell Lines
Landry ML, Ferguson D, Cohen S, Peret TC, Erdman DD. Detection of Human Metapneumovirus in Clinical Samples by Immunofluorescence Staining of Shell Vial Centrifugation Cultures Prepared from Three Different Cell Lines. Journal Of Clinical Microbiology 2005, 43: 1950-1952. PMID: 15815029, PMCID: PMC1081324, DOI: 10.1128/jcm.43.4.1950-1952.2005.Peer-Reviewed Original Research
1998
Lack of reactivity to CMV pp65 antigenemia testing in a patient with CMV disease following allogeneic bone marrow transplant
Seropian S, Ferguson D, Salloum E, Cooper D, Landry M. Lack of reactivity to CMV pp65 antigenemia testing in a patient with CMV disease following allogeneic bone marrow transplant. Bone Marrow Transplantation 1998, 22: 507-509. PMID: 9733277, DOI: 10.1038/sj.bmt.1701354.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, ViralBone Marrow TransplantationCytomegalovirusCytomegalovirus InfectionsHumansMalePhosphoproteinsViral Matrix ProteinsConceptsPeripheral blood leukocytesAntigenemia testingCMV diseaseCMV infectionAntiviral therapyBlood leukocytesPre-emptive antiviral therapyAllogeneic bone marrow transplantationAllogeneic bone marrow transplantAntibody poolEarly detectionCMV pp65 antigenemiaBone marrow transplantationBone marrow transplantPeripheral blood specimensPeripheral blood samplesAllogeneic BMTLiver transaminasesPp65 antigenemiaAbnormal transaminasesMarrow transplantationMarrow transplantViral cultureAplastic anemiaBronchial lavagePapular-Purpuric Gloves and Socks Syndrome Associated with Acute Parvovirus B19 Infection: Case Report and Review
Smith P, Landry M, Carey H, Krasnoff J, Cooney E. Papular-Purpuric Gloves and Socks Syndrome Associated with Acute Parvovirus B19 Infection: Case Report and Review. Clinical Infectious Diseases 1998, 27: 164-168. PMID: 9675471, DOI: 10.1086/514629.Peer-Reviewed Original ResearchConceptsAcute parvovirus B19 infectionPapular-purpuric glovesParvovirus B19 infectionParvovirus B19B19 infectionCases of PPGSSTypical clinical syndromeSerial serologyAcute phaseOral erosionsSocks syndromeConvalescent periodIgM antibodiesSyndrome AssociatedClinical syndromeCase reportUnusual syndromeSyndromeDermatology literatureInfectionCausative agentPPGSSB19AntibodiesMost cases
1993
Comparison of latex agglutination test with enzyme-linked immunosorbent assay for detection of antibody to varicella-zoster virus
Landry ML, Ferguson D. Comparison of latex agglutination test with enzyme-linked immunosorbent assay for detection of antibody to varicella-zoster virus. Journal Of Clinical Microbiology 1993, 31: 3031-3033. PMID: 8263191, PMCID: PMC266199, DOI: 10.1128/jcm.31.11.3031-3033.1993.Peer-Reviewed Original Research
1984
Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections
Hsiung GD, Landry ML, Mayo DR, Fong C. Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections. Clinics In Dermatology 1984, 2: 67-82. PMID: 6100717, DOI: 10.1016/0738-081x(84)90067-1.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, ViralCells, CulturedCytopathogenic Effect, ViralDNA Restriction EnzymesFluorescent Antibody TechniqueHerpes GenitalisHerpes LabialisHerpes SimplexHumansImmunoenzyme TechniquesInclusion Bodies, ViralMicroscopy, ElectronNucleic Acid HybridizationSimplexvirusSpecimen HandlingVirionConceptsHerpes simplex virusHSV infectionHSV-2Virus isolationRecurrence of diseaseCommon viral infectionsEffective antiviral therapyType 2 infectionHerpes simplex virus type 1Simplex virus type 1HSV-1 infectionVirus type 1Fever blistersHSV isolationHerpetic lesionsAntiviral therapyClinical findingsGenital lesionsCommon manifestationDrug reactionsAllergic reactionsSevere diseaseGenital areaSimplex virusInfection results