2015
Association of COPD With Risk for Pulmonary Infections Requiring Hospitalization in HIV-Infected Veterans
Attia EF, McGinnis KA, Feemster LC, Akgün KM, Butt AA, Graber CJ, Fine MJ, Goetz MB, Rodriguez-Barradas MC, Pisani MA, Tindle HA, Brown ST, Hoo G, Rimland D, Gibert CL, Huang L, Freiberg MS, Hough CL, Crothers K. Association of COPD With Risk for Pulmonary Infections Requiring Hospitalization in HIV-Infected Veterans. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 70: 280-288. PMID: 26181820, PMCID: PMC4607625, DOI: 10.1097/qai.0000000000000751.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCommunity-acquired pneumoniaPneumocystis jirovecii pneumoniaIndependent risk factorIncidence rate ratiosPulmonary infectionRisk factorsAssociation of COPDBurden of COPDVeterans Aging Cohort Study Virtual CohortRisk of CAPMultivariable Poisson regression modelsBaseline comorbid conditionsDifferent pulmonary infectionsInfections Requiring HospitalizationCD4 cell countHIV viral loadChronic lung diseaseObstructive pulmonary diseaseMultivariable Poisson regressionUnadjusted incidence rateNinth Revision codesPoisson regression modelsJirovecii pneumoniaPulmonary tuberculosis
2011
Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy
Akgün KM, Huang L, Morris A, Justice AC, Pisani M, Crothers K. Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy. Annals Of The American Thoracic Society 2011, 8: 301-307. PMID: 21653532, PMCID: PMC3132789, DOI: 10.1513/pats.201009-060wr.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyICU admissionCritical illnessAdministration of ARTImpact of ARTProportion of deathsHIV eraOpportunistic infectionsHIVAIDS epidemicMore recent studiesIllnessPatientsAdmissionTherapyRecent studiesICUEtiologyInfectionMortalityIncidenceDiseaseAdministrationThe Changing Epidemiology of HIV-Infected Patients in the Intensive Care Unit
Akgün KM, Pisani M, Crothers K. The Changing Epidemiology of HIV-Infected Patients in the Intensive Care Unit. Journal Of Intensive Care Medicine 2011, 26: 151-164. PMID: 21436170, DOI: 10.1177/0885066610387996.Peer-Reviewed Original ResearchConceptsPneumocystis jirovecii pneumoniaImpact of HAARTICU admissionRespiratory failureIntensive care unit admissionOutcome of HIVActive antiretroviral therapyCare unit admissionLow serum albuminPoor functional statusInflammatory response syndromeIntensive care unitHAART administrationHAART initiationHospital mortalityMedication toxicityUnit admissionAntiretroviral therapyICU mortalityICU survivalComorbid diseasesHIV diagnosisJirovecii pneumoniaCommon indicationResponse syndrome