2024
Pharmacological management of gambling disorder: an update of the literature
Mestre-Bach G, Potenza M. Pharmacological management of gambling disorder: an update of the literature. Expert Review Of Neurotherapeutics 2024, 24: 391-407. PMID: 38357896, DOI: 10.1080/14737175.2024.2316833.Peer-Reviewed Original ResearchGambling disorderCo-occurring disordersSerotonin reuptake inhibitorsPlacebo response ratesOpioid receptor antagonistMental health conditionsGlutamatergic agentsNeurobiological correlatesGambling subtypesMood stabilizersReuptake inhibitorsClasses of medicationsPharmacological treatmentBetting behaviorGamblingTreatment responsePharmacological interventionsDisordersPharmacological managementMedicationTreatment optionsNarrative reviewLongitudinal informationResponse rateNalmefene
2022
Glutamatergic Agents for the Treatment of Cocaine Use Disorder
Hadizadeh H, Flores J, Mayerson T, Worhunsky P, Potenza M, Angarita G. Glutamatergic Agents for the Treatment of Cocaine Use Disorder. Current Behavioral Neuroscience Reports 2022, 9: 101-112. DOI: 10.1007/s40473-022-00252-1.Peer-Reviewed Original ResearchCocaine use disorderRoute of administrationGlutamatergic systemSafety profileNovel agentsUse disordersMetabotropic glutamate receptor 5 antagonistNewer beta-lactam agentsAMPA/kainate receptorsTreatment of CUDBeta-lactam agentsGood safety profileMetabotropic glutamate receptorsPromising preclinical dataReceptors/transportersChronic cocaine useGLT-1 transporterBeta-lactam antibioticsOngoing trialsPreclinical supportGlutamatergic agentsGlutamate neurotransmissionPreclinical dataClinical trialsGlutamate receptorsNovel Pharmacological Agents for the Treatment of Cocaine Use Disorder
Hadizadeh H, Flores J, Nunes E, Mayerson T, Potenza M, Angarita G. Novel Pharmacological Agents for the Treatment of Cocaine Use Disorder. Current Behavioral Neuroscience Reports 2022, 9: 27-46. DOI: 10.1007/s40473-022-00246-z.Peer-Reviewed Original ResearchCocaine use disorderNovel pharmacological agentsUse disordersCocaine vaccinePharmacological agentsClinical supportNarrative reviewAlpha-adrenergic antagonistKappa-opioid receptorsCorticotropin-releasing factorCentral nervous systemPurpose of reviewClinical evidenceGlutamatergic agentsSerotonergic agentsCholinergic agentsOrexin antagonistsNeurobiological targetsDopamine pathwayArousal pathwayNervous systemExtension studyPromising agentCapacity of cocaineDisorders