Significance of 1B and 2B domains in modulating elastic properties of lamin A
Bera M, Ainavarapu S, Sengupta K. Significance of 1B and 2B domains in modulating elastic properties of lamin A. Scientific Reports 2016, 6: 27879. PMID: 27301336, PMCID: PMC4908593, DOI: 10.1038/srep27879.Peer-Reviewed Original ResearchConceptsLamin ASingle-molecule force spectroscopyRod domainType V intermediate filament proteinsLamin rod domainsSingle molecular levelInner nuclear membraneC-terminal domainIntermediate filament proteinsForce spectroscopyNuclear laminsLaminsNuclear membraneFilament proteinsElastic meshworkNuclear shapeMutationsComparable mechanical propertiesDomainViscoelastic behaviorSpectroscopyLaminopathiesProperties