2013
Intravenous ketamine for the treatment of refractory status epilepticus: A retrospective multicenter study
Gaspard N, Foreman B, Judd LM, Brenton JN, Nathan BR, McCoy BM, Al‐Otaibi A, Kilbride R, Fernández IS, Mendoza L, Samuel S, Zakaria A, Kalamangalam GP, Legros B, Szaflarski JP, Loddenkemper T, Hahn CD, Goodkin HP, Claassen J, Hirsch LJ, LaRoche SM. Intravenous ketamine for the treatment of refractory status epilepticus: A retrospective multicenter study. Epilepsia 2013, 54: 1498-1503. PMID: 23758557, PMCID: PMC3731413, DOI: 10.1111/epi.12247.Peer-Reviewed Original ResearchConceptsRefractory status epilepticusTreatment of RSEIntravenous ketamineStatus epilepticusBrain injuryEpisodes of RSEPostanoxic brain injuryAnoxic brain injuryMulticenter retrospective reviewRetrospective multicenter studyRole of ketaminePossible adverse eventsAcademic medical centerKetamine initiationProspective trialAdverse eventsRetrospective reviewRetrospective seriesSE onsetMulticenter studyLast drugMedical recordsMedical CenterSafe drugConcurrent drugs
2002
Levetiracetam May Be More Effective for Late-Onset Partial Epilepsy
Bazil CW, Rose A, Resor S, Yapicular B, Hirsch LJ. Levetiracetam May Be More Effective for Late-Onset Partial Epilepsy. JAMA Neurology 2002, 59: 1905-1908. PMID: 12470178, DOI: 10.1001/archneur.59.12.1905.Peer-Reviewed Original ResearchConceptsLevetiracetam therapySeizure typesRetrospective medical record reviewFrontal lobe onsetSame seizure typesTemporal lobe onsetLarge prospective trialsMedical record reviewSubset of patientsPopulation of patientsLocalization-related epilepsyNew antiepileptic drugsProspective trialRefractory epilepsyRecord reviewAntiepileptic drugsPartial epilepsySignificant worseningDrug choiceClinical experiencePatientsEpileptic seizuresEpilepsyCertain drugsCertain subpopulations