2021
Neuromodulation in epilepsy: state-of-the-art approved therapies
Ryvlin P, Rheims S, Hirsch LJ, Sokolov A, Jehi L. Neuromodulation in epilepsy: state-of-the-art approved therapies. The Lancet Neurology 2021, 20: 1038-1047. PMID: 34710360, DOI: 10.1016/s1474-4422(21)00300-8.Peer-Reviewed Original ResearchConceptsVagus nerve stimulationANT-DBSAdverse eventsNeuromodulation therapiesResponsive neurostimulationCurative surgical treatmentFrequent adverse eventsRefractory focal epilepsyHigh-level evidenceDeep brain stimulationForms of neuromodulationClosed-loop therapyAntiepileptic treatmentSeizure frequencySurgical treatmentNerve stimulationIntracranial hemorrhageIntractable seizuresEpileptogenic zoneFocal epilepsyAnterior nucleusLong-term reductionBrain stimulationTherapyImplant sites
2007
To Sleep, Perchance to Seize: Surgery Ameliorates Nocturnal Frontal Lobe Seizures
Hirsch LJ. To Sleep, Perchance to Seize: Surgery Ameliorates Nocturnal Frontal Lobe Seizures. Epilepsy Currents 2007, 8: 12-14. PMID: 18265881, PMCID: PMC2238651, DOI: 10.1111/j.1535-7511.2007.00219.x.Peer-Reviewed Original ResearchFocal cortical dysplasiaExcessive daytime sleepinessPre-surgical evaluationSleep-related seizuresFrontal lobe seizuresEpileptogenic zoneStereo-EEGFrontal lobeAccurate pre-surgical evaluationComprehensive pre-surgical evaluationScalp video-EEG monitoringTaylor's focal cortical dysplasiaClass IIDrug-resistant focal epilepsyTaylor-type focal cortical dysplasiaEngel class IAEngel Class IIIctal clinical signsNocturnal frontal lobe epilepsyVideo-EEG monitoringClass IaFrontal lobe originNocturnal frontal lobe seizuresFrontal lobe epilepsyInvasive EEG recordings