2015
Dictyostelium discoideum has a highly Q/N-rich proteome and shows an unusual resilience to protein aggregation
Malinovska L, Palm S, Gibson K, Verbavatz J, Alberti S. Dictyostelium discoideum has a highly Q/N-rich proteome and shows an unusual resilience to protein aggregation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: e2620-e2629. PMID: 25941378, PMCID: PMC4443358, DOI: 10.1073/pnas.1504459112.Peer-Reviewed Original ResearchMeSH KeywordsDictyosteliumElectrophoresis, Polyacrylamide GelFluorescence Recovery After PhotobleachingHumansHuntingtin ProteinMicroscopy, ElectronMicroscopy, FluorescenceNerve Tissue ProteinsPeptide Termination FactorsPrionsProtein Aggregation, PathologicalProteomeProteostasis DeficienciesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsConceptsPrion-like proteinsD. discoideumMolecular chaperonesDictyostelium discoideumHuntingtin exon 1Yeast prion protein Sup35Prion-like domainsOverall aggregation propensityProtein-misfolding diseasesUbiquitin-proteasome systemPrion protein Sup35Rich proteomeHsp100 familyCellular proteostasisPrion stateCytosolic aggregatesSequence similarityPrion domainBioinformatics toolsProtein aggregationProteostatic capacityDiscoideumAggregation propensityProteomePrion protein
2011
The RabGAP Proteins Gyp5p and Gyl1p Recruit the BAR Domain Protein Rvs167p for Polarized Exocytosis
Prigent M, Boy‐Marcotte E, Chesneau L, Gibson K, Dupré‐Crochet S, Tisserand H, Verbavatz J, Cuif M. The RabGAP Proteins Gyp5p and Gyl1p Recruit the BAR Domain Protein Rvs167p for Polarized Exocytosis. Traffic 2011, 12: 1084-1097. PMID: 21554509, DOI: 10.1111/j.1600-0854.2011.01218.x.Peer-Reviewed Original ResearchMeSH KeywordsExocytosisGlucan Endo-1,3-beta-D-GlucosidaseGTPase-Activating ProteinsMicrofilament ProteinsMutationNerve Tissue ProteinsProlineProtein BindingProtein Interaction Domains and MotifsRab GTP-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSecretory VesiclesSrc Homology Domains