2009
Lower-leg symptoms in peripheral arterial disease are associated with anxiety, depression, and anhedonia
Smolderen KG, Hoeks SE, Pedersen SS, van Domburg RT, de Liefde II, Poldermans D. Lower-leg symptoms in peripheral arterial disease are associated with anxiety, depression, and anhedonia. Vascular Medicine 2009, 14: 297-304. PMID: 19808714, DOI: 10.1177/1358863x09104658.Peer-Reviewed Original ResearchConceptsAtypical leg symptomsPeripheral arterial diseaseExertional leg symptomsAnkle-brachial indexLeg symptomsIntermittent claudicationDepressive symptomsPAD patientsClinical factorsArterial diseaseAnkle-brachial index screeningSan Diego Claudication QuestionnaireClassic intermittent claudicationConsecutive PAD patientsLower leg symptomsDiverse clinical manifestationsErasmus Medical CenterMood statesSub-threshold symptomsCardiovascular historyMedication useTwofold riskClinical manifestationsPoor prognosisHospital Anxiety
2008
Depressive symptoms in peripheral arterial disease: A follow-up study on prevalence, stability, and risk factors
Smolderen KG, Aquarius AE, de Vries J, Smith OR, Hamming JF, Denollet J. Depressive symptoms in peripheral arterial disease: A follow-up study on prevalence, stability, and risk factors. Journal Of Affective Disorders 2008, 110: 27-35. PMID: 18237784, DOI: 10.1016/j.jad.2007.12.238.Peer-Reviewed Original ResearchConceptsAnkle-brachial indexPeripheral arterial diseaseDepressive symptomsPAD patientsArterial diseaseRisk factorsDepressed patientsSymptomatic lower extremity peripheral arterial diseaseLower extremity peripheral arterial diseaseEpidemiological Studies Depression ScaleTreadmill walking distanceCardiovascular risk factorsCoronary artery diseasePsychotropic medication useRelevant depressive symptomsOnly baseline dataPAD severityArtery diseaseMedication usePatient groupPoor prognosisClinical correlatesDepression ScaleClinical careWalking distance