2020
E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1
Pham K, Huynh D, Le L, Delitto D, Yang L, Huang J, Kang Y, Steinberg MB, Li J, Zhang L, Liu D, Tang MS, Liu C, Wang H. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Letters 2020, 491: 132-145. PMID: 32829009, PMCID: PMC9703643, DOI: 10.1016/j.canlet.2020.08.010.Peer-Reviewed Original ResearchConceptsBC cell growthCig exposureLung metastasesBreast cancerVCAM-1V-CAM-1Role of CCL5Upregulated protein expressionBC cell survivalE-cig exposurePro-tumorigenic factorsBC cell apoptosisBreast carcinoma progressionMetastatic lung colonizationCCR5 axisMFP tumorsTAMs infiltrationInfiltrated macrophagesCell growthCo-culture systemImmunohistochemical stainsCell crosstalkBC cellsBC growthProliferation index
2012
CCL5, CCR1 and CCR5 in murine glioblastoma: Immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5
Pham K, Luo D, Liu C, Harrison JK. CCL5, CCR1 and CCR5 in murine glioblastoma: Immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5. Journal Of Neuroimmunology 2012, 246: 10-17. PMID: 22425022, PMCID: PMC3335967, DOI: 10.1016/j.jneuroim.2012.02.009.Peer-Reviewed Original ResearchConceptsMicroglia/macrophagesGlioblastoma multiformeImmune cell infiltrationMalignant brain tumorsTumor bearing miceHuman glioblastoma multiformeMet-CCL5Cell infiltrationMurine glioblastomaCCR5 antagonistsBearing miceBrain tumorsCCR5Survival rateGlioblastoma microenvironmentTumor progressionCCR1CCL5MacrophagesGlioblastomaLymphocytesAntagonistMultiformeTumorsMice