Targeting the site encoded by SERPINA1*E342K for treating alpha‐1 antitrypsin deficiency‐associated liver diseases
Zhang X, Pham K, Li D, Schutte RJ, Brantly M, Liu C, Ostrov DA. Targeting the site encoded by SERPINA1*E342K for treating alpha‐1 antitrypsin deficiency‐associated liver diseases. FEBS Letters 2019, 593: 1849-1862. PMID: 31116417, DOI: 10.1002/1873-3468.13452.Peer-Reviewed Original ResearchConceptsLiver diseaseAlpha1-antitrypsin deficiencyLiver pathologyAAT deficiencyHepatocellular carcinomaClinical utilityIntracellular accumulationE342K mutationK mutation