2024
Trends in American Indian/Alaskan native self-reported stroke prevalence and associated modifiable risk factors in the United States from 2011-2021
Heath T, Shrishail N, Wong K, Johnston K, Sharma R, Ney J, Sheth K, de Havenon A. Trends in American Indian/Alaskan native self-reported stroke prevalence and associated modifiable risk factors in the United States from 2011-2021. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107650. PMID: 38460776, PMCID: PMC11253029, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107650.Peer-Reviewed Original ResearchBehavioral Risk Factor Surveillance SystemSelf-reported strokeModifiable vascular risk factorsVascular risk factorsPrevalence of strokeStroke prevalenceRisk factorsPrevalence of self-reported strokeWhite adultsBehavioral Risk Factor Surveillance System surveyRisk Factor Surveillance SystemPersistent health disparitiesAmerican Indian/Alaskan NativesSurvey of adultsModifiable risk factorsHigher overall burdenSurvey-weighted prevalenceUnited StatesHealth disparitiesRace/ethnic groupsRisk of strokeAI/ANOverall burdenRate of strokeSelf-report
2023
Improvement in the Prediction of Cerebrovascular Events With White Matter Hyperintensity
de Havenon A, Smith E, Sharma R, Falcone G, Bangad A, Prabhakaran S, Sheth K. Improvement in the Prediction of Cerebrovascular Events With White Matter Hyperintensity. Journal Of The American Heart Association 2023, 12: e029374. PMID: 37345754, PMCID: PMC10356061, DOI: 10.1161/jaha.123.029374.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesIncident strokePrimary outcomeHypertensive individualsMatter hyperintensitiesAtherosclerotic cardiovascular disease risk scoreCognitive impairmentCardiovascular disease risk scoreVascular risk factorsCurrent cigarette smokingDisease risk scoreMagnetic resonance imagingLogistic regression modelsRandomization armCerebrovascular eventsVascular riskCigarette smokingPrognostic informationRisk factorsPrognostic abilityRisk scoreCognitive declineResonance imagingDeLong testStrokeIdentification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMagnetic resonance imagingSevere white matter hyperintensitiesConventional magnetic resonance imagingResonance imagingRetrospective cohortEmergency departmentMatter hyperintensitiesVascular risk factorsProspective observational studyVascular cognitive impairmentTesla magnetic resonance imagingArea Deprivation IndexProspective cohortAdult patientsAcute careRisk factorsCardiovascular diseaseObservational studyCognitive impairmentPatientsCare magnetic resonance imagingIntermodality agreementCohortDeprivation index
2022
Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic
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Sripathi S, Chaitanya S, Agrawal K, Baghel V, Patel K, Dalili N, Nafa M, Matsuda W, Suzuki R, Kyo M, Tahara S, Hayakawa M, Maekawa K, Suzuki R, Sanui M, Horikita S, Itagaki Y, Kodate A, Suzuki R, Kodate A, Takahashi Y, Moriki K, Shiga T, Iwasaki Y, Shigemitsu H, Mishima Y, Nosaka N, Nagashima M, Al-Fares A, Rodriguez-Gutierrez R, Gonzalez-Gonzalez J, Salcido-Montenegro A, Camacho-Ortiz A, Ulloa M, Hassan-Hanga F, Galadanci H, Gezawa A, Kabara H, Amole T, Kabir H, Haliru D, Ibrahim A, Asghar M, Syed M, Naqvi S, Zabolotskikh I, Zybin K, Sinkov S, Musaeva T, Alamoudi R, AlSharif H, Almazwaghi S, Elsakran M, Aid M, Darwich M, Hagag O, Ali S, rocacorba A, Supeña K, Juane E, Medina J, Baduria J, Amer M, Abdullah M, Bawazeer T, Kseibi E, Butt A, Khurshid S, Rabee M, Abujazar M, Alghunaim R, Abualkhair M, AlFirm A, Kseibi E, Khurshid S, Rabee M, Abujazar M, Alghunaim R, Arabi Y, Abdukahil S, Almazyad M, Alarifi M, Macarambon J, Bukhari A, Albahrani H, Asfina K, Aldossary K, Zdravkovic M, Todorovic Z, Popadic V, Klasnja S, Andrijevic A, Gavrilovic S, Carapic V, Kovacevic B, Bojicic J, Predrag S, Stojakov D, Ignjatovic D, Bojic S, Bobos M, Nenadic I, Zaric M, Djuric M, Djukic V, Teruel S, Martin B, Teruel S, Sili U, Bilgin H, Ay P, Gharpure V, Raheemi U, Dodd K, Goodmanson N, Hesse K, Bird P, Weinert C, Schoenrade N, Altaher A, Mayar E, Aronson M, Cooper T, Logan M, Miner B, Papo G, Siegal E, Runningen P, Barry S, Woll C, Wu G, Carrole E, Burke K, Mohammed M, Melamed R, Tierney D, Patel L, Raj V, Dawud B, Mazumder N, Sidebottom A, Guenther A, Krehbiel B, Schmitz N, Jepsen S, Sipsey L, Schulte A, Wunderlich W, Hoyt C, Raval A, Franks A, Irby K, Sanders R, Hefley G, Jarvis J, Kharbanda A, Jhajhria S, Fyffe Z, Capizzi S, Alicie B, Green M, Crockarell L, Drennan A, Dubuque K, Fambrough T, Gasaway N, Krantz B, Nebi P, Orga J, Serfass M, Simion A, Warren K, Wheeler C, Woolman C, Christie A, Ashley D, Adiga R, Moyer A, Verghese G, Newsome A, Forehand C, Bruning R, Jones T, 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S, Burns S, Raymond A, Gonyaw E, Hodgdon K, Housenger C, Lin B, McQuesten K, Pecott-Grimm H, Sweet J, Ventrone S, Khandelwal N, West T, Caldwell E, Lovelace-Macon L, Garimella N, Dow D, Cheruku S, Chen C, Ahmed F, Deonarine C, Jones A, Preston D, Shaikh M, Chin J, Akhter M, Rahman R, Mulrow M, Wilfong E, Vela K, Khanna A, Harris L, Cusson B, Fowler J, Vaneenenaam D, McKinney G, Udoh I, Johnson K, Lyons P, Michelson A, Haluf S, Lynch L, Nguyen N, Steinberg A, Braus N, Pattan V, Papke J, Jimada I, Mhid N, Chakola S, Sheth K, Ammar A, Ammar M, Lopez V, Dela Cruz C, Khosla A, Gautam S. Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic. Critical Care Explorations 2022, 4: e0686. PMID: 35492258, PMCID: PMC9042584, DOI: 10.1097/cce.0000000000000686.Peer-Reviewed Original ResearchSerious neurologic manifestationsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSyndrome coronavirus 2 infectionSARS-CoV-2 infectionMeningitis/encephalitisCoronavirus 2 infectionNeurologic manifestationsHospitalized patientsRisk factorsWorse outcomesSevere diseaseLaboratory-confirmed SARS-CoV-2 infectionMedian age 72 yearsHospital discharge statusVentilator-free daysCritical care interventionsProspective observational studyVascular risk factorsChronic medical conditionsAge 72 yearsCOVID-19 registryCOVID-19 infectionDisease Severity ScaleCare interventionsWORSE VASCULAR RISK FACTOR CONTROL IN PATIENTS WITH STROKE COMPARED TO PATIENTS WITH MYOCARDIAL INFARCTION
Leasure A, Acosta J, Schwartz A, Forman R, Sharma R, de Havenon A, Falcone G, Inzucchi S, Kernan W, Sheth K. WORSE VASCULAR RISK FACTOR CONTROL IN PATIENTS WITH STROKE COMPARED TO PATIENTS WITH MYOCARDIAL INFARCTION. Journal Of The American College Of Cardiology 2022, 79: 1504. DOI: 10.1016/s0735-1097(22)02495-0.Peer-Reviewed Original Research
2019
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Chauhan G, Adams H, Satizabal C, Bis J, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith A, Jian X, Malik R, Traylor M, Pulit S, Amouyel P, Mazoyer B, Zhu Y, Kaffashian S, Schilling S, Beecham G, Montine T, Schellenberg G, Kjartansson O, Guðnason V, Knopman D, Griswold M, Windham B, Gottesman R, Mosley T, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan K, Aggarwal N, De Jager P, Evans D, Psaty B, Rotter J, Rice K, Lopez O, Liao J, Chen C, Cheng C, Wong T, Ikram M, van der Lee S, Amin N, Chouraki V, DeStefano A, Aparicio H, Romero J, Maillard P, DeCarli C, Wardlaw J, del C. 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Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology 2019, 92: 10.1212/wnl.0000000000006851. PMID: 30651383, PMCID: PMC6369905, DOI: 10.1212/wnl.0000000000006851.Peer-Reviewed Original ResearchPopulation-based cohortGenetic risk scoreBrain infarctsLifestyle risk factorsRisk factorsWhite matter hyperintensity burdenLarge population-based cohortPrevious cardiovascular diseaseVascular risk factorsPopulation-based settingBody mass indexSex-adjusted associationsCausal risk factorPopulation-based participantsAdditional large datasetsGenome-wide association studiesIschemic strokeBlood pressureRelated phenotypesHigh BPMass indexBP traitsCardiovascular diseaseRisk scoreGenetic risk loci