2023
Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006)
Olexa M, Begunova Y, Bartolome D, Peng T, Matouk C, Sheth K, Petersen N. Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202997.Peer-Reviewed Original ResearchHemorrhagic Conversion of Acute Ischemic Stroke
Zubair A, Sheth K. Hemorrhagic Conversion of Acute Ischemic Stroke. Neurotherapeutics 2023, 20: 705-711. PMID: 37085684, PMCID: PMC10275827, DOI: 10.1007/s13311-023-01377-1.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeHemorrhagic conversionIschemic strokeTreatment of patientsHemorrhagic transformationEndovascular thrombectomySerious complicationsThrombolytic therapyTreatment optionsRisk factorsLeading causePatient outcomesCurrent treatmentTimely managementStrokePatientsTreatmentThrombectomyMorbidityComplicationsReviewPathophysiologyTherapyMortalityDiagnosis
2021
How to Establish the Outer Limits of Reperfusion Therapy
Wechsler L, Jadhav A, Jovin T, Adeoye O, Albers G, Ansari S, Boltze J, Buchan A, Campbell B, Chaisinanunkul N, Chen C, Derdeyn C, Haddad W, Hill M, Holt W, Houser G, Khatri P, Krtolica A, Landen J, Lansberg M, Liebeskind D, Lyden P, Lynch J, Meinzer C, Mistry E, Mocco J, Nogueira R, Saver J, Savitz S, Schwamm L, Sheth K, Snyder M, Solberg Y, Vagal A, Venkatasubramanian C, Warach S, Ziogas N. How to Establish the Outer Limits of Reperfusion Therapy. Stroke 2021, 52: 3399-3403. PMID: 34470484, DOI: 10.1161/strokeaha.121.035022.Peer-Reviewed Original ResearchConceptsReperfusion therapyAcute ischemic strokeLarge pragmatic trialRoutine clinical practiceDrug Administration approvalTreatment effectsIntravenous alteplaseIschemic strokeStroke onsetEndovascular therapyRandomized trialsPragmatic trialImaging featuresAdministration approvalPlatform trialsSignificant treatment effectEffective treatmentTreatment efficacyAcademic centersClinical practiceTherapyPatientsTrialsMedical communityStatistical significance
2019
Poor Collaterals and Malignant CT Perfusion Profiles Are Associated with Increased Vulnerability to Blood Pressure Reductions during Endovascular Therapy (S57.002)
Strander S, Payabvash S, Wang A, Kodali S, Silverman A, Agarwal T, Stretz C, Zheng-Lin B, Cardenas G, Sansing L, Schindler J, Matouk C, Hebert R, Sheth K, Gutierrez S, Petersen N. Poor Collaterals and Malignant CT Perfusion Profiles Are Associated with Increased Vulnerability to Blood Pressure Reductions during Endovascular Therapy (S57.002). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s57.002.Peer-Reviewed Original Research
2018
105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome
Mampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome. Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.Peer-Reviewed Original ResearchDecreases in Blood Pressure During Endovascular Stroke Therapy are Common and Associated with Poor Functional Outcome (S21.004)
Wang A, Mampre D, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. Decreases in Blood Pressure During Endovascular Stroke Therapy are Common and Associated with Poor Functional Outcome (S21.004). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s21.004.Peer-Reviewed Original ResearchImpaired cerebral autoregulation after endovascular stroke therapy is associated with hemorrhagic transformation (S40.003)
Petersen N, Wang A, Marshall R, Mampre D, Tan C, Sheth K. Impaired cerebral autoregulation after endovascular stroke therapy is associated with hemorrhagic transformation (S40.003). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s40.003.Peer-Reviewed Original ResearchCharacteristics of Surrogate Decision Makers Selecting Life-sustaining Therapy for Severe Intracerebral Hemorrhage Patients: a Neuropalliative Care Survey of the US Population (S7.003)
Hwang D, Knies A, White D, Holloway R, Sheth K, Fraenkel L. Characteristics of Surrogate Decision Makers Selecting Life-sustaining Therapy for Severe Intracerebral Hemorrhage Patients: a Neuropalliative Care Survey of the US Population (S7.003). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.s7.003.Peer-Reviewed Original Research