2023
Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry
Murthy S, Zhang C, Shah S, Schwamm L, Fonarow G, Smith E, Bhatt D, Ziai W, Kamel H, Sheth K. Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry. Stroke 2023, 54: 2972-2980. PMID: 37942641, PMCID: PMC10842167, DOI: 10.1161/strokeaha.123.043194.Peer-Reviewed Original ResearchConceptsIschemic vascular diseaseProportion of patientsGuidelines-Stroke registryLipid-lowering therapyIntracerebral hemorrhageVascular diseaseStatin therapyAnticoagulation therapyCardiovascular eventsAtrial fibrillationFuture major cardiovascular eventsLower admission National InstitutesPrevious lipid-lowering therapyAdmission National InstitutesFavorable discharge outcomeIschemic cardiovascular eventsHealth Stroke ScaleMajor cardiovascular eventsLipid-lowering medicationsCross-sectional studyMultiple logistic regressionLogistic regression analysisAntiplatelet medicationsAntiplatelet therapyStatin medicationEffects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials
Salman R, Stephen J, Tierney J, Lewis S, Newby D, Parry-Jones A, White P, Connolly S, Benavente O, Dowlatshahi D, Cordonnier C, Viscoli C, Sheth K, Kamel H, Veltkamp R, Larsen K, Hofmeijer J, Kerkhoff H, Schreuder F, Shoamanesh A, Klijn C, van der Worp H, Haemorrhage C, Klug D, Casolla B, Puy L, Coffee M, Kuchcinski G, Labreuche J, van Nieuwenhuizen K, Algra A, van Gelder I, Kappelle L, Rinkel G, Schutgens R, Khatri P, Conwit R, Falcone G, Elm J, Anderson C, Song L, Pandian J, Hart R, Sharma M, Aref H, Tarhuni W, Fabregas J, Diener H, Endres M, Lemmens R, Kwon S, Lee B, Ameriso S, Milling T, Kasner S, Mikulik R, Xavier D, Beer R, Toni D, Eckstein J, Seiffge D, Ferro J, Tsivgoulis G, Sharma S, Wei-Liou C, Hohnloser S, Katsanos A, Bosch J, Healey J, Eikelboom J, Khaw A, Gladstone D, Pikula A, Coutts S, Smith E, Butcher K, Field T, Gioia L, Stapf C, Halse O, Ringleb P, Enzinger C, Sibon I, Montaner J, Caso V, Heuschmann P, Lip G, Haefeli W, Debette S, Dennis M, Wyller T, Rønning O, Eilertsen H, Ihle-Hansen H, Sandset E, Pennlert J, Glader E, Kruuse C, Wester P, Carlsson M, Forfang E. Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials. The Lancet Neurology 2023, 22: 1140-1149. PMID: 37839434, DOI: 10.1016/s1474-4422(23)00315-0.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsSpontaneous intracranial hemorrhageOral anticoagulationCardiovascular eventsIntracranial hemorrhageAtrial fibrillationCardiovascular deathIndividual participant dataEligible trialsHazard ratioPrimary outcomeOngoing trialsFixed-effect inverse variance modelParticipant dataDirect oral anticoagulantsOral anticoagulant agentsCochrane systematic reviewCox regression modelPrevious intracranial hemorrhageInverse variance modelBritish Heart FoundationLong-term useSubgroup of participantsAntiplatelet monotherapyRacial and Ethnic Differences in the Risk of Ischemic Stroke After Nontraumatic Intracerebral Hemorrhage
Simonetto M, Sheth K, Ziai W, Iadecola C, Zhang C, Murthy S. Racial and Ethnic Differences in the Risk of Ischemic Stroke After Nontraumatic Intracerebral Hemorrhage. Stroke 2023, 54: 2401-2408. PMID: 37462054, PMCID: PMC10529487, DOI: 10.1161/strokeaha.123.043160.Peer-Reviewed Original ResearchConceptsNon-Hispanic white patientsNon-Hispanic blacksIschemic strokeIntracerebral hemorrhageHispanic patientsWhite patientsAtrial fibrillationICH patientsHigh riskNon-Hispanic black patientsCox proportional hazards modelIncident ischemic strokeRetrospective cohort studyNontraumatic intracerebral hemorrhageValvular heart diseaseTime of dischargeLarge heterogeneous cohortProportional hazards modelNon-Hispanic whitesICH hospitalizationsCardiovascular comorbiditiesMedian followCohort studyVascular comorbiditiesConcomitant diagnosisEffect of Alteplase on Ischemic Stroke Mortality Is Dependent on Stroke Severity
de Havenon A, Abbasi M, Yaghi S, Delic A, Bangad A, Johnston K, Tirschwell D, Sheth K. Effect of Alteplase on Ischemic Stroke Mortality Is Dependent on Stroke Severity. Annals Of Neurology 2023, 93: 1106-1116. PMID: 36852919, DOI: 10.1002/ana.26621.Peer-Reviewed Original ResearchConceptsIV-tPAHigher NIHSSIschemic strokeAtrial fibrillationNational Inpatient Sample (NIS) 2016Non-Hispanic white raceOlder ageBaseline National InstitutesDEFUSE-3 trialsHealth Stroke ScalePost-stroke mortalityIschemic stroke mortalityEffect of alteplaseRisk of mortalityLogistic regression modelsAnn NeurolFAST-MAGIMS IIISevere ISHospital mortalityIntravenous alteplaseSevere strokeStroke ScaleStroke severityFunctional outcome
2021
Sex Differences in Ablation Strategy, Lesion Sets, and Complications of Catheter Ablation for Atrial Fibrillation: An Analysis From the GWTG-AFIB Registry
Yunus F, Perino A, Holmes D, Matsouaka R, Curtis A, Ellenbogen K, Frankel D, Knight B, Russo A, Lewis W, Piccini J, Turakhia M, Day J, Desai N, Feld G, Fonarow G, Hurwitz J, Joglar J, Sheth K, Sidhu M. Sex Differences in Ablation Strategy, Lesion Sets, and Complications of Catheter Ablation for Atrial Fibrillation: An Analysis From the GWTG-AFIB Registry. Circulation Arrhythmia And Electrophysiology 2021, 14: e009790. PMID: 34719235, DOI: 10.1161/circep.121.009790.Peer-Reviewed Original ResearchConceptsAblation strategyNonparoxysmal AFLesion setsPatient sexInitial AF ablation procedureAdvanced atrial diseaseAtrial linear ablationNonpulmonary vein triggersQuality improvement registryAF ablation proceduresAtrial fibrillation ablationOptimal ablation strategyAF ablation strategiesAF ablationPatient demographicsCatheter ablationFibrillation ablationMultivariable analysisAtrial diseaseAtrial fibrillationLinear ablationAF typeAblation proceduresComplicationsPatientsExtracranial Hemorrhage in the Setting of Gastrointestinal or Genitourinary Cancer is Associated with Increased Risk of Ischemic Stroke in Patients with Atrial Fibrillation (1373)
Zhou E, Lord A, Boehme A, Henninger N, De Havenon A, Vahidy F, Ishida K, Torres J, Mistry E, Mac Grory B, Sheth K, Gurol E, Furie K, Elkind M, Yaghi S. Extracranial Hemorrhage in the Setting of Gastrointestinal or Genitourinary Cancer is Associated with Increased Risk of Ischemic Stroke in Patients with Atrial Fibrillation (1373). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.1373.Peer-Reviewed Original Research
2019
Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Collaborators G, Johnson C, Nguyen M, Roth G, Nichols E, Alam T, Abate D, Abd-Allah F, Abdelalim A, Abraha H, Abu-Rmeileh N, Adebayo O, Adeoye A, Agarwal G, Agrawal S, Aichour A, Aichour I, Aichour M, Alahdab F, Ali R, Alvis-Guzman N, Anber N, Anjomshoa M, Arabloo J, Arauz A, Ärnlöv J, Arora A, Awasthi A, Banach M, Barboza M, Barker-Collo S, Bärnighausen T, Basu S, Belachew A, Belayneh Y, Bennett D, Bensenor I, Bhattacharyya K, Biadgo B, Bijani A, Bikbov B, Bin Sayeed M, Butt Z, Cahuana-Hurtado L, Carrero J, Carvalho F, Castañeda-Orjuela C, Castro F, Catalá-López F, Chaiah Y, Chiang P, Choi J, Christensen H, Chu D, Cortinovis M, Damasceno A, Dandona L, Dandona R, Daryani A, Davletov K, de Courten B, De la Cruz-Góngora V, Degefa M, Dharmaratne S, Diaz D, Dubey M, Duken E, Edessa D, Endres M, FARAON E, Farzadfar F, Fernandes E, Fischer F, Flor L, Ganji M, Gebre A, Gebremichael T, Geta B, Gezae K, Gill P, Gnedovskaya E, Gómez-Dantés H, Goulart A, Grosso G, Guo Y, Gupta R, Haj-Mirzaian A, Haj-Mirzaian A, Hamidi S, Hankey G, Hassen H, Hay S, Hegazy M, Heidari B, Herial N, Hosseini M, Hostiuc S, Irvani S, Islam M, Jahanmehr N, Javanbakht M, Jha R, Jonas J, Jozwiak J, Jürisson M, Kahsay A, Kalani R, Kalkonde Y, Kamil T, Kanchan T, Karch A, Karimi N, Karimi-Sari H, Kasaeian A, Kassa T, Kazemeini H, Kefale A, Khader Y, Khalil I, Khan E, Khang Y, Khubchandani J, Kim D, Kim Y, Kisa A, Kivimäki M, Koyanagi A, Krishnamurthi R, Kumar G, Lafranconi A, Lewington S, Li S, Lo W, Lopez A, Lorkowski S, Lotufo P, Mackay M, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Manafi N, Mansournia M, Mehndiratta M, Mehta V, Mengistu G, Meretoja A, Meretoja T, Miazgowski B, Miazgowski T, Miller T, Mirrakhimov E, Mohajer B, Mohammad Y, Mohammadoo-khorasani M, Mohammed S, Mohebi F, Mokdad A, Mokhayeri Y, Moradi G, Morawska L, Velásquez I, Mousavi S, Muhammed O, Muruet W, Naderi M, Naghavi M, Naik G, Nascimento B, Negoi R, Nguyen C, Nguyen L, Nirayo Y, Norrving B, Noubiap J, Ofori-Asenso R, Ogbo F, Olagunju A, Olagunju T, Owolabi M, Pandian J, Patel S, Perico N, Piradov M, Polinder S, Postma M, Poustchi H, Prakash V, Qorbani M, Rafiei A, Rahim F, Rahimi K, Rahimi-Movaghar V, Rahman M, Rahman M, Reis C, Remuzzi G, Renzaho A, Ricci S, Roberts N, Robinson S, Roever L, Roshandel G, Sabbagh P, Safari H, Safari S, Safiri S, Sahebkar A, Zahabi S, Samy A, Santalucia P, Santos I, Santos J, Milicevic M, Sartorius B, Sawant A, Schutte A, Sepanlou S, Shafieesabet A, Shaikh M, Shams-Beyranvand M, Sheikh A, Sheth K, Shibuya K, Shigematsu M, Shin M, Shiue I, Siabani S, Sobaih B, Sposato L, Sutradhar I, Sylaja P, Szoeke C, Ao B, Temsah M, Temsah O, Thrift A, Tonelli M, Topor-Madry R, Tran B, Tran K, Truelsen T, Tsadik A, Ullah I, Uthman O, Vaduganathan M, Valdez P, Vasankari T, Vasanthan R, Venketasubramanian N, Vosoughi K, Vu G, Waheed Y, Weiderpass E, Weldegwergs K, Westerman R, Wolfe C, Wondafrash D, Xu G, Yadollahpour A, Yamada T, Yatsuya H, Yimer E, Yonemoto N, Yousefifard M, Yu C, Zaidi Z, Zamani M, Zarghi A, Zhang Y, Zodpey S, Feigin V, Vos T, Murray C. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology 2019, 18: 439-458. PMID: 30871944, PMCID: PMC6494974, DOI: 10.1016/s1474-4422(19)30034-1.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-standardised incidenceSocio-demographic IndexSDI quintileGlobal burdenMortality rateAge-standardised DALY ratesTransient ischemic attackBurden of strokePost-stroke careDisease Study 2016Risk Factor StudyCause-specific mortalityNew stroke casesVerbal autopsy dataYears of lifeEstimates of burdenIschemic attackSDI groupCause of diseaseGBD 2016DALY ratesHaemorrhagic strokeIntracerebral hemorrhageAtrial fibrillation