The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort
Singh S, Oreskovic T, Carr S, Papier K, Conroy M, Senff J, Chemali Z, Gutierrez-Martinez L, Parodi L, Mayerhofer E, Marini S, Nunley C, Newhouse A, Ouyang A, Brouwers H, Westover B, Rivier C, Falcone G, Howard V, Howard G, Pikula A, Ibrahim S, Sheth K, Yechoor N, Lazar R, Anderson C, Tanzi R, Fricchione G, Littlejohns T, Rosand J. The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort. Frontiers In Neurology 2023, 14: 1291020. PMID: 38107629, PMCID: PMC10725202, DOI: 10.3389/fneur.2023.1291020.Peer-Reviewed Original ResearchRisk of dementiaIncident casesIncident dementiaCare scoresLower riskCox proportional hazards regressionSubsequent incident dementiaProportional hazards regressionUK Biobank cohortHazards regressionBaseline evaluationSignificant associationAge groupsDementiaBiobank cohortStrokeDelphi processLifestyle choicesPatientsUKB participantsRiskBaselineBehavior changeAssociationPredictive validityTwenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Status
de Havenon A, Zhou L, Johnston K, Dangayach N, Ney J, Yaghi S, Sharma R, Abbasi M, Delic A, Majersik J, Anadani M, Tirschwell D, Sheth K. Twenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Status. Neurology 2023, 101: e464-e474. PMID: 37258298, PMCID: PMC10401675, DOI: 10.1212/wnl.0000000000207446.Peer-Reviewed Original ResearchConceptsStroke death ratesSocial deprivation indexSocial determinantsDeath rateOlder individualsYoung individualsCounty-level social determinantsHigher social deprivation indexDeprivation indexNon-Hispanic white individualsPublic health strategiesHigher substance abuseMedical insurance coverageCounty-level increasesRace/ethnicityStroke deathsStroke mortalityBlack raceDistinct social determinantsHealth strategiesAge groupsDisease controlSubstance abusePercentage changeSocioeconomic status