1990
Processing and intracellular sorting of anglerfish and rat preprosomatostatins in mammalian endocrine cells
Sevarino K, Ventimiglia R, Stork P. Processing and intracellular sorting of anglerfish and rat preprosomatostatins in mammalian endocrine cells. Metabolism 1990, 39: 26-29. PMID: 1976215, DOI: 10.1016/0026-0495(90)90203-o.Peer-Reviewed Original Research
1989
Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity
Sevarino K, Stork P, Ventimiglia R, Mandel G, Goodman R. Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity. Cell 1989, 57: 11-19. PMID: 2564811, DOI: 10.1016/0092-8674(89)90167-0.Peer-Reviewed Original ResearchConceptsEndocrine cell linesRat preprosomatostatinCarboxy-terminal thirdDistinct cell typesAmino-terminal sequenceCell linesHybrid proteinLeader sequenceIntracellular targetingRegulated pathwayPreprosomatostatin 1Cellular factorsExpression vectorCell typesPattern of processingProcessing siteBioactive peptidesAnglerfish isletsSequenceDifferential processingPeptidesProteinResiduesPathwayHigh levels