1989
Characterization and Expression of the Gene‐Encoding Rat Thyrotropin‐Releasing Hormone (TRH)
LEE S, SEVARINO K, ROOS B, GOODMAN R. Characterization and Expression of the Gene‐Encoding Rat Thyrotropin‐Releasing Hormone (TRH). Annals Of The New York Academy Of Sciences 1989, 553: 14-28. PMID: 2497670, DOI: 10.1111/j.1749-6632.1989.tb54475.x.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernBlotting, SouthernBrainCloning, MolecularDNAEnhancer Elements, GeneticGenesMolecular Sequence DataOrgan SpecificityPromoter Regions, GeneticProtein PrecursorsRatsRecombinant Fusion ProteinsRestriction MappingRNA, MessengerThyrotropin-Releasing HormoneTransfection
1986
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.
Montminy M, Sevarino K, Wagner J, Mandel G, Goodman R. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 6682-6686. PMID: 2875459, PMCID: PMC386573, DOI: 10.1073/pnas.83.18.6682.Peer-Reviewed Original ResearchConceptsRat somatostatin geneSomatostatin geneCAMP responsivenessReporter gene encoding chloramphenicolTranscriptional initiation siteProtein kinase 2Promoter deletion mutantsSimian virus 40 promoterSomatostatin gene promoterCAMP-responsive elementPC12 rat pheochromocytoma cellsKinase 2 activityGene encoding chloramphenicolTranscriptional regulationDeletion mutantsChimeric genePromoter elementsGene promoterGene expressionKinase 2Rat pheochromocytoma cellsInitiation siteResponsive elementGenesBase pairs