Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers
Jacokes Z, Adoremos I, Hussain A, Newman B, Pelphrey K, Van Horn J. Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers. 2024, 614-630. DOI: 10.1142/9789819807024_0044.Peer-Reviewed Original ResearchAutism spectrum disorderNeural basisDevelopmental disabilitiesCognitive traitsDiagnostic disparitiesSpectrum disorderNeuroimaging techniquesASD biomarkersSex differencesSocial functioningASD researchEffects of gene expressionNeuronal microstructureTailored interventionsBiological influencesGenetic interactionsGene expressionPhenotypic heterogeneityAutismCognitionPrincipal component analysisEarly‐ and Late‐Stage Auditory Processing of Speech Versus Non‐Speech Sounds in Children With Autism Spectrum Disorder: An ERP and Oscillatory Activity Study
Edgar E, McGuire K, Pelphrey K, Ventola P, van Noordt S, Crowley M. Early‐ and Late‐Stage Auditory Processing of Speech Versus Non‐Speech Sounds in Children With Autism Spectrum Disorder: An ERP and Oscillatory Activity Study. Developmental Psychobiology 2024, 66: e22552. PMID: 39508446, DOI: 10.1002/dev.22552.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNon-speech soundsSpeech soundsTD childrenSpectrum disorderCortical activityResponses to speech soundsProcessing stagesSensitivity to speechAtypical auditory processingTheta phase coherenceAuditory speech processingP3a amplitudeAuditory speechIntra-individual variabilityDevelopment of cortical networksASD childrenCortical networksSpeech processingAuditory processingElectroencephalography sessionLanguage processingCortical responsesAutismSpeechDisentangling negative and positive symptoms in schizophrenia and autism spectrum disorder
Corbera S, Wexler B, Bell M, Pittman B, Pelphrey K, Pearlson G, Assaf M. Disentangling negative and positive symptoms in schizophrenia and autism spectrum disorder. Schizophrenia Research 2024, 271: 1-8. PMID: 39002525, PMCID: PMC11384336, DOI: 10.1016/j.schres.2024.07.002.Peer-Reviewed Original ResearchAutism spectrum disorderPositive and Negative Syndrome ScaleAutism Diagnostic Observation Schedule-GenericExperiential negative symptomsPositive symptomsNegative symptomsExploratory factor analysisSpectrum disorderNegative Syndrome ScaleTarget negative symptomsSyndrome ScaleDiscriminant function analysisSZ relativesAssociated with quality of lifeSchizophreniaSocial skillsSocial functioningDiagnostic classificationAutismFactor analysisAssociated with qualityPredictor of diagnosisSymptomsDisordersQuality of lifeTime is of the essence: Age at autism diagnosis, sex assigned at birth, and psychopathology
Smith J, McQuaid G, Wallace G, Neuhaus E, Lopez A, Ratto A, Jack A, Khuu A, Webb S, Verbalis A, Pelphrey K, Kenworthy L. Time is of the essence: Age at autism diagnosis, sex assigned at birth, and psychopathology. Autism 2024, 28: 2909-2922. PMID: 38725306, PMCID: PMC11496012, DOI: 10.1177/13623613241249878.Peer-Reviewed Original ResearchSymptoms of anxiety/depressionDepressive symptomsIdentification of autismCommunity-based sampleAnxious/depressed symptomsClinic-based sampleInclusionary criteriaAutism diagnosisAutismClinic-basedMental healthSymptomsAnxiety/depressionSex-basedPsychopathologyAnxietySexIndividualsMaleAge-based disparitiesFemalesBoys/menDiagnostic ageGirls/womenResearchGender, assigned sex at birth, and gender diversity: Windows into diagnostic timing disparities in autism
McQuaid G, Ratto A, Jack A, Khuu A, Smith J, Duane S, Clawson A, Lee N, Verbalis A, Pelphrey K, Kenworthy L, Wallace G, Strang J. Gender, assigned sex at birth, and gender diversity: Windows into diagnostic timing disparities in autism. Autism 2024, 28: 2806-2820. PMID: 38587289, PMCID: PMC11458814, DOI: 10.1177/13623613241243117.Peer-Reviewed Original ResearchGender identityGender diversityGender diverse peopleGender diverse populationsAutism diagnosisReduce mental health risksFemale sexMental health problemsCisgender peopleClinic-based sampleMental health risksAutistic peopleAssociated with riskAutism diagnosis in adulthoodAssigned sexClinic-basedDiagnosis in adulthoodHealth problemsGenderAutistic sampleFemale genderIdentityAutismPeopleMale gender