Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk.
Murnane P, Afshar M, Chamie G, Cook R, Ferguson T, Haque L, Jacobson K, Justice A, Kim T, Khalili M, Krupitsky E, McGinnis K, Molina P, Muyindike W, Myers B, Richards V, So-Armah K, Stewart S, Sulkowski M, Tien P, Hahn J. Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk. The American Journal Of Gastroenterology 2024 PMID: 39480054, DOI: 10.14309/ajg.0000000000003178.Peer-Reviewed Original ResearchLiver fibrosis riskAUDIT-CFIB-4Self-reported alcohol useOdds ratioAlcohol useFibrosis riskPooled individual-level dataLiver fibrosis preventionBody mass indexAssessment of alcohol useManagement of liver diseaseOne-unit differenceIndividual-level dataMedian ageAUDIT-C.Mass indexSuppression statusLiver diseaseFibrosis preventionBlood concentrationsAdjusted modelsLogistic regressionCategorical variablesHIVCombining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration
McGinnis K, Justice A, Marconi V, Rodriguez-Barradas M, Hauser R, Oursler K, Brown S, Bryant K, Tate J, Study F. Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration. Frontiers In Medicine 2024, 10: 1342466. PMID: 38356736, PMCID: PMC10864663, DOI: 10.3389/fmed.2023.1342466.Peer-Reviewed Original ResearchCharlson Comorbidity IndexVACS IndexHIV RNAVeterans Health AdministrationComorbid diseasesNon-AIDS conditionsCongestive heart failureAssociated with CD4Risk of mortalityMedian ageHepatitis C.Older age groupsCharlson comorbidityCD4Prognostic accuracyHeart failurePWoHComorbidity indexVA careKidney diseasePWHHIVMatched comparatorsBaseline predictorsClinical biomarkers