FRAP Analysis Reveals Stabilization of Adhesion Structures in the Epidermis Compared to Cultured Keratinocytes
Foote HP, Sumigray KD, Lechler T. FRAP Analysis Reveals Stabilization of Adhesion Structures in the Epidermis Compared to Cultured Keratinocytes. PLOS ONE 2013, 8: e71491. PMID: 23977053, PMCID: PMC3747223, DOI: 10.1371/journal.pone.0071491.Peer-Reviewed Original ResearchMeSH KeywordsAdherens JunctionsAnimalsCadherinsCell AdhesionCells, CulturedDesmoplakinsEpidermal CellsEpidermisFluorescence Recovery After PhotobleachingGene Knock-In TechniquesGreen Fluorescent ProteinsKeratinocytesMiceProtein IsoformsZonula Occludens-1 ProteinConceptsAdherens junctionsAdhesion structuresCell-cell adhesion structuresAdherens junction protein E-cadherinJunction protein E-cadherinCell-cell junctionsE-cadherinProtein E-cadherinDesmosomal protein desmoplakinZO-1Tight junctionsTissue morphogenesisTissue maintenanceFRAP analysisAdhesion functionProtein ZO-1Photobleaching experimentsProper developmentTight junction protein ZO-1Fluorescence recoveryCultured cellsDynamics of adhesionEpithelial tissuesCurrent understandingCell cultures