2022
Adherence to Guidelines in Heart Failure, Is It Valid for Elderly Patients?
Khoury J, Ghersin I, Braun E, Elias A, Aronson D, Azzam Z, Bahouth F. Adherence to Guidelines in Heart Failure, Is It Valid for Elderly Patients? Israel Medical Association Journal 2022, 24: 757-762. PMID: 36436045.Peer-Reviewed Original ResearchConceptsAcute decompensated heart failureAngiotensin receptor blockersPatients 80 yearsEjection fractionHeart failureMedicine groupSingle-center retrospective studyDecompensated heart failureReduced ejection fractionLarge prospective studiesRandomized clinical trialsOlder adult populationGDMT groupMineralocorticoid antagonistsCause mortalityReceptor blockersValue of guidelinesElderly patientsHospital dischargeOlder patientsYounger patientsMedical therapyPrimary outcomeProspective studyRetrospective study
2019
Long-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome
Awadie H, Khoury J, Zohar Y, Yaccob A, Veitsman E, Saadi T. Long-term Follow-up of Severe Eosinophilic Hepatitis: A Rare Presentation of Hypereosinophilic Syndrome. Rambam Maimonides Medical Journal 2019, 10: e0020. PMID: 31545703, PMCID: PMC6824826, DOI: 10.5041/rmmj.10374.Peer-Reviewed Original ResearchEuropean Medicines AgencyYounger patientsPediatric studiesLong-term Follow-upYoung personFDA black box warningBlack box warningYoung depressed patientsDrug developmentInstitutional review boardEosinophilic hepatitisHypereosinophilic syndromePlacebo treatmentDevelopmental pharmacologyRare presentationFollow-upDepressed patientsDiscrimination of childrenDrug treatmentAdult depressionEffective drugsEfficacy studiesUS FoodDrug AdministrationMedicines Agency