Stage-specific translational efficiency and protein stability regulate the developmental expression of p37, an RNA binding protein from Trypanosoma brucei
Li J, Ruyechan WT, Williams N. Stage-specific translational efficiency and protein stability regulate the developmental expression of p37, an RNA binding protein from Trypanosoma brucei. Biochemical And Biophysical Research Communications 2003, 306: 918-923. PMID: 12821129, DOI: 10.1016/s0006-291x(03)01084-2.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGene Expression RegulationPrecipitin TestsProtein BiosynthesisProtozoan ProteinsRecombinant ProteinsRNARNA-Binding ProteinsTime FactorsTrypanosoma brucei bruceiConceptsProcyclic stageP37 proteinVivo metabolic labelingRNA binding proteinPost-translational levelDifferential stabilityCysteine protease activityProcyclic cellsSignificant homologyBloodstream cellsDevelopmental regulationNovel RNAProtein stabilityTrypanosoma bruceiTranslational efficiencyMetabolic labelingPredominant proteinDevelopmental expressionBinding proteinP37P34ProteinProtease activityRNACells