2020
Facility Variation in Troponin Ordering Within the Veterans Health Administration
Chui PW, Esserman D, Bastian LA, Curtis JP, Gandhi PU, Rosman L, Desai N, Hauser RG. Facility Variation in Troponin Ordering Within the Veterans Health Administration. Medical Care 2020, 58: 1098-1104. PMID: 33003051, PMCID: PMC7666100, DOI: 10.1097/mlr.0000000000001424.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAge FactorsAgedAged, 80 and overComorbidityCross-Sectional StudiesDiagnosis-Related GroupsEmergency Service, HospitalGuideline AdherenceHumansMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Sex FactorsSocioeconomic FactorsTroponinUnited StatesUnited States Department of Veterans AffairsConceptsDownstream resource utilizationVeterans Health AdministrationCase mixHealth AdministrationCurrent United States guidelinesDownstream health care utilizationVeterans Health Administration facilitiesFacility characteristicsAcute coronary syndromeEmergency department visitsPercutaneous coronary interventionHealth care utilizationAcute care facilitiesUnited States guidelinesHigh rateCross-sectional analysisCoronary syndromeCoronary interventionED visitsDepartment visitsCare utilizationHighest quartileCoronary angiogramInpatient admissionsLowest quartile
2017
Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack
Young LH, Viscoli CM, Curtis JP, Inzucchi SE, Schwartz GG, Lovejoy AM, Furie KL, Gorman MJ, Conwit R, Abbott JD, Jacoby DL, Kolansky DM, Pfau SE, Ling FS, Kernan WN. Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack. Circulation 2017, 135: 1882-1893. PMID: 28246237, PMCID: PMC5511545, DOI: 10.1161/circulationaha.116.024863.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeType 1 myocardial infarctionTransient ischemic attackMyocardial infarctionCoronary syndromeInsulin resistanceIschemic attackIschemic strokeDiabetes mellitusSerum troponinAcute coronary syndrome episodeMean age 63 yearsAcute coronary syndrome eventIndependent clinical events committeeType 2 myocardial infarctionIRIS participantsImpact of pioglitazoneRecent cerebrovascular eventsRecent ischemic strokeClinical events committeeAge 63 yearsEffect of pioglitazoneSmall myocardial infarctionCoronary artery diseaseST-segment elevation
2016
Trends in U.S. Cardiovascular Care 2016 Report From 4 ACC National Cardiovascular Data Registries
Masoudi FA, Ponirakis A, de Lemos JA, Jollis JG, Kremers M, Messenger JC, Moore JWM, Moussa I, Oetgen WJ, Varosy PD, Vincent RN, Wei J, Curtis JP, Roe MT, Spertus JA. Trends in U.S. Cardiovascular Care 2016 Report From 4 ACC National Cardiovascular Data Registries. Journal Of The American College Of Cardiology 2016, 69: 1427-1450. PMID: 28025065, DOI: 10.1016/j.jacc.2016.12.005.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overCardiologyDefibrillators, ImplantableFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionRegistriesConceptsCardiovascular diseaseAdult congenital heart diseaseNational Cardiovascular Data RegistryAcute coronary syndromePercutaneous coronary interventionCongenital heart diseaseOutcomes of careQuality of careMeasure of ProcessesCoronary syndromeClinical characteristicsCoronary interventionCardiac catheterizationHeart diseaseLeading causeData registryDiseaseCardiovascular dataPatientsRegistryBroader populationCareInterventionOutcomesReport
2015
The predicament of comparative effectiveness research using observational data.
Curtis JP, Krumholz HM. The predicament of comparative effectiveness research using observational data. Annals Of Internal Medicine 2015, 163: 799-800. PMID: 26501410, PMCID: PMC6467208, DOI: 10.7326/m15-2490.Commentaries, Editorials and LettersAcute Coronary SyndromeComparative Effectiveness ResearchCoronary AngiographyHumansObservational Studies as Topic
2012
Cellularity and structure of fresh human coronary thrombectomy specimens; presence of cells with markers of progenitor cells
Jovin IS, Lei L, Huang Y, Hao Z, Curtis JP, Brennan JJ, Remetz MS, Setaro JF, Pfau SE, Howes CJ, Clancy JF, Cabin HS, Cleman MW, Giordano FJ. Cellularity and structure of fresh human coronary thrombectomy specimens; presence of cells with markers of progenitor cells. Journal Of Cellular And Molecular Medicine 2012, 16: 3022-3027. PMID: 22947374, PMCID: PMC4393730, DOI: 10.1111/j.1582-4934.2012.01629.x.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCoronary thrombectomyCoronary syndromeProgenitor cellsCholesterol crystalsAcute myocardial infarctionEndothelial progenitor cellsFormation of thrombiHaematopoietic progenitor cellsVon Willebrand factorInflammatory cellsEndothelial cell mediumMyocardial infarctionPlaque ruptureThrombectomyImmunohistochemical analysisVascular wallPresence of cellsBlood cellsWillebrand factorThrombusDevelopment of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention
Curtis JP, Geary LL, Wang Y, Chen J, Drye EE, Grosso LM, Spertus JA, Rumsfeld JS, Weintraub WS, Masoudi FA, Brindis RG, Krumholz HM. Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Quality And Outcomes 2012, 5: 628-637. PMID: 22949491, DOI: 10.1161/circoutcomes.111.964569.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAngina PectorisChi-Square DistributionComorbidityFemaleHeart DiseasesHospital MortalityHospitalsHumansLogistic ModelsMaleMyocardial InfarctionOdds RatioOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionQuality Indicators, Health CareRegistriesRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionRisk-standardized mortality ratesElevation myocardial infarctionPatient mortality ratesMyocardial infarctionMortality rateCardiogenic shockCoronary interventionDerivation cohortHospital risk-standardized mortality ratesCause mortality ratesAdministrative claims dataQuality of careHierarchical logistic regression modelsNational Quality ForumLogistic regression modelsObserved mortality rateCathPCI RegistryNational HospitalClaims dataInfarctionPatientsQuality ForumFinal model
2011
Factors Associated With 30-Day Readmission Rates After Percutaneous Coronary Intervention
Khawaja FJ, Shah ND, Lennon RJ, Slusser JP, Alkatib AA, Rihal CS, Gersh BJ, Montori VM, Holmes DR, Bell MR, Curtis JP, Krumholz HM, Ting HH. Factors Associated With 30-Day Readmission Rates After Percutaneous Coronary Intervention. JAMA Internal Medicine 2011, 172: 112-117. PMID: 22123752, PMCID: PMC3688066, DOI: 10.1001/archinternmed.2011.569.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngina, UnstableAngioplasty, Balloon, CoronaryCoronary Artery BypassEducational StatusFemaleFollow-Up StudiesHeart FailureHumansIschemic Attack, TransientKidney DiseasesLength of StayMaleMedicareMultivariate AnalysisMyocardial InfarctionNeoplasm MetastasisPatient ReadmissionPeptic UlcerProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveRegistriesSex FactorsStrokeUnited StatesConceptsPercutaneous coronary interventionThirty-day readmissionReadmission ratesCoronary interventionHigh riskChronic obstructive pulmonary diseaseThirty-day readmission ratesCox proportional hazards modelMultivariate logistic regression modelTransient ischemic attackCongestive heart failureObstructive pulmonary diseasePeptic ulcer diseaseSevere renal diseaseAcute myocardial infarctionLength of stayMain outcome measuresProportional hazards modelSaint Mary's HospitalLogistic regression modelsIschemic attackTime-dependent covariatesUnstable anginaCerebrovascular accidentHeart failure
2008
Implementation and Integration of Prehospital ECGs Into Systems of Care for Acute Coronary Syndrome
Ting HH, Krumholz HM, Bradley EH, Cone DC, Curtis JP, Drew BJ, Field JM, French WJ, Gibler WB, Goff DC, Jacobs AK, Nallamothu BK, O'Connor RE, Schuur JD. Implementation and Integration of Prehospital ECGs Into Systems of Care for Acute Coronary Syndrome. Circulation 2008, 118: 1066-1079. PMID: 18703464, DOI: 10.1161/circulationaha.108.190402.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements