2019
Body mass index and outcomes of cardiac resynchronization with implantable cardioverter‐defibrillator therapy in older patients with heart failure
Echouffo‐Tcheugui J, Masoudi FA, Bao H, Curtis JP, Heidenreich PA, Fonarow GC. Body mass index and outcomes of cardiac resynchronization with implantable cardioverter‐defibrillator therapy in older patients with heart failure. European Journal Of Heart Failure 2019, 21: 1093-1102. PMID: 31359595, DOI: 10.1002/ejhf.1552.Peer-Reviewed Original ResearchConceptsBody mass indexDevice-related complicationsNormal weightMass indexNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryImplantable cardioverter-defibrillator therapyClass III obesityHeart failure outcomesCardioverter-defibrillator therapyObesity class IObesity class IICardiac resynchronization therapyObesity class IIIHF patientsUnderweight patientsDefibrillator implantationElderly patientsHazard ratioObese patientsOlder patientsBMI categoriesHeart failureResynchronization therapyCardiac resynchronizationAssociation of body mass index with cardiac resynchronization therapy intention and left ventricular lead implantation failure: insights from the NCDR implantable cardioverter-defibrillator registry
Nishimura M, Marcus GM, Varosy PD, Bao H, Wang Y, Curtis JP, Hsu JC. Association of body mass index with cardiac resynchronization therapy intention and left ventricular lead implantation failure: insights from the NCDR implantable cardioverter-defibrillator registry. Journal Of Interventional Cardiac Electrophysiology 2019, 57: 279-288. PMID: 31004224, DOI: 10.1007/s10840-019-00550-x.Peer-Reviewed Original ResearchConceptsBody mass indexLV lead placementLead placementImplantation failureMass indexExtreme obesityBody habitusHigher oddsNational Cardiovascular Data Registry ICD RegistryImplantable Cardioverter-Defibrillator RegistrySuccessful LV lead placementPatient body mass indexWorld Health Organization classificationBackgroundCardiac resynchronization therapyNormal weight patientsVentricular lead placementCRT-D therapyPatient body habitusHierarchical logistic regressionEligible patientsWeight patientsMultivariable adjustmentClinical characteristicsDefibrillator implantationBiventricular pacing
2015
Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study)
Gupta A, Chui P, Zhou S, Spertus JA, Geda M, Lorenze N, Lee I, Onofrio G, Lichtman JH, Alexander KP, Krumholz HM, Curtis JP. Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study). The American Journal Of Cardiology 2015, 116: 1-7. PMID: 25937348, PMCID: PMC4466069, DOI: 10.1016/j.amjcard.2015.03.032.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAngioplasty, Balloon, CoronaryAnticoagulantsAntithrombinsBody Mass IndexCohort StudiesFemaleHemorrhageHeparinHirudinsHumansMaleMiddle AgedMyocardial InfarctionPeptide FragmentsPercutaneous Coronary InterventionPlatelet Glycoprotein GPIIb-IIIa ComplexPrevalenceRecombinant ProteinsRisk AssessmentRisk FactorsSex DistributionTreatment OutcomeUnited StatesConceptsPercutaneous coronary interventionGlycoprotein IIb/IIIa inhibitorsIIb/IIIa inhibitorsExcess dosingAcute myocardial infarctionCoronary interventionMultivariable analysisMyocardial infarctionUnderwent Percutaneous Coronary InterventionLower body weightOlder patientsYounger patientsUnfractionated heparinMedical recordsUnivariate analysisAnticoagulant agentsAnticoagulant drugsBody weightPatientsDosingYounger ageLogistic regressionYoung womenAnticoagulantsGender-based differences
2014
Risk Stratification for Long-Term Mortality After Percutaneous Coronary Intervention
Wu C, Camacho FT, King SB, Walford G, Holmes DR, Stamato NJ, Berger PB, Sharma S, Curtis JP, Venditti FJ, Jacobs AK, Hannan EL. Risk Stratification for Long-Term Mortality After Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2014, 7: 80-87. PMID: 24425588, PMCID: PMC4121885, DOI: 10.1161/circinterventions.113.000475.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCox proportional hazards modelLong-term mortalityProportional hazards modelSimple risk scoreRisk of deathRisk scoreHazards modelCoronary interventionVital statusRisk factorsCoronary artery bypass graft surgeryArtery bypass graft surgeryExtreme body mass indexPoint-based risk scorePreprocedural risk factorsSimplified risk scoreUnstable hemodynamic stateBypass graft surgeryLow ejection fractionNational Death IndexBody mass indexPatients' vital statusSeparate risk factorsMultivessel disease
2012
Low Body Mass Index but Not Obesity Is Associated With In‐Hospital Adverse Events and Mortality Among Implantable Cardioverter‐Defibrillator Recipients: Insights From the National Cardiovascular Data Registry
Hsu JC, Varosy PD, Bao H, Wang Y, Curtis JP, Marcus GM. Low Body Mass Index but Not Obesity Is Associated With In‐Hospital Adverse Events and Mortality Among Implantable Cardioverter‐Defibrillator Recipients: Insights From the National Cardiovascular Data Registry. Journal Of The American Heart Association 2012, 1: e003863. PMID: 23316325, PMCID: PMC3540679, DOI: 10.1161/jaha.112.003863.Peer-Reviewed Original ResearchConceptsBody mass indexNormal weight patientsFirst-time ICD recipientsWeight patientsAdverse eventsICD recipientsHospital deathHospital stayUnderweight patientsICD implantationObese patientsMass indexNational Cardiovascular Data Registry ICD RegistryAssociation of BMINational Cardiovascular Data RegistryLower body mass indexImplantable cardioverter defibrillator recipientsHierarchical multivariable logistic regressionMore periprocedural complicationsHospital adverse eventsMultivariable logistic regressionSudden cardiac deathPatient body habitusReal-world populationHospital complications
2005
The Obesity Paradox: Body Mass Index and Outcomes in Patients With Heart Failure
Curtis JP, Selter JG, Wang Y, Rathore SS, Jovin IS, Jadbabaie F, Kosiborod M, Portnay EL, Sokol SI, Bader F, Krumholz HM. The Obesity Paradox: Body Mass Index and Outcomes in Patients With Heart Failure. JAMA Internal Medicine 2005, 165: 55-61. PMID: 15642875, DOI: 10.1001/archinte.165.1.55.Peer-Reviewed Original ResearchConceptsBody mass indexHeart failureDigitalis Investigation Group trialBaseline body mass indexStable heart failureStudy of patientsLean patientsObese patientsMass indexHealthy weightAdverse outcomesChronic diseasesGroup trialsGeneral populationStable outpatientsBetter outcomesPatientsOutcomesOverweightObesityOutpatientsDiseaseTrials