2024
Association of Physician Certification and Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
Vora A, Pereira L, Du C, Tan Z, Huang C, Friedman D, Wang Y, Faridi K, Lakkireddy D, Zimmerman S, Higgins A, Kapadia S, Curtis J, Freeman J. Association of Physician Certification and Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion. JACC Cardiovascular Interventions 2024 PMID: 39474982, DOI: 10.1016/j.jcin.2024.10.020.Peer-Reviewed Original ResearchPhysician certificationAppendage occlusionAdverse eventsPercutaneous left atrial appendage occlusionLong-term oral anticoagulationDischarged patientsMultivariate Cox proportional hazards regression analysisRate of procedural complicationsLeft atrial appendage occlusionCox proportional hazards regression analysisProportional hazards regression analysisRisk of adverse eventsHazards regression analysisIn-hospital deathOral anticoagulantsWatchman FLXNo significant differenceLAAO devicesProcedural complicationsStratify patientsIntracardiac echocardiographyAtrial fibrillationEligible patientsIdentified patientsMultivariable adjustment
2023
Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes
Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.Peer-Reviewed Original ResearchConceptsEligible patientsICD RegistryCardiac resynchronizationNational Cardiovascular Data Registry ICD RegistryCRT-D implantationCRT-D useHospital-level outcomesStrong guideline recommendationsHospital-level variationPatient-level outcomesIntraclass correlation coefficientQuality improvement effortsHospital mortalityGuideline indicationsReadmission ratesSelect patientsClinical outcomesGuideline recommendationsHospital variationHospital ratesUse of CRTHospital levelHospital usePatientsCase mix
2022
HP-573-04 VARIATION IN HOSPITAL USE OF CRT-D AMONG ELIGIBLE PATIENTS AND ASSOCIATION WITH CLINICAL OUTCOMES
Chui P, Lan Z, Curtis J. HP-573-04 VARIATION IN HOSPITAL USE OF CRT-D AMONG ELIGIBLE PATIENTS AND ASSOCIATION WITH CLINICAL OUTCOMES. Heart Rhythm 2022, 19: s44-s45. DOI: 10.1016/j.hrthm.2022.03.668.Peer-Reviewed Original Research
2019
Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block
Kawata H, Bao H, Curtis JP, Minges KE, Mitiku T, Birgersdotter-Green U, Feld GK, Hsu JC. Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block. Journal Of The American College Of Cardiology 2019, 73: 3082-3099. PMID: 31221257, DOI: 10.1016/j.jacc.2019.04.025.Peer-Reviewed Original ResearchConceptsNonspecific intraventricular conduction delayRight bundle branch blockCardiac resynchronization therapyCRT-D implantationCRT-eligible patientsBundle branch blockQRS durationHazard ratioBranch blockBetter outcomesCardiac resynchronization defibrillator therapyMultivariable adjusted hazard ratiosAdjusted hazard ratioIntraventricular conduction delayCareful patient selectionEligible patientsDefibrillator therapyMultivariable adjustmentResynchronization therapyClinical outcomesPatient selectionConduction abnormalitiesRegistry dataConduction delayPatientsAssociation of body mass index with cardiac resynchronization therapy intention and left ventricular lead implantation failure: insights from the NCDR implantable cardioverter-defibrillator registry
Nishimura M, Marcus GM, Varosy PD, Bao H, Wang Y, Curtis JP, Hsu JC. Association of body mass index with cardiac resynchronization therapy intention and left ventricular lead implantation failure: insights from the NCDR implantable cardioverter-defibrillator registry. Journal Of Interventional Cardiac Electrophysiology 2019, 57: 279-288. PMID: 31004224, DOI: 10.1007/s10840-019-00550-x.Peer-Reviewed Original ResearchConceptsBody mass indexLV lead placementLead placementImplantation failureMass indexExtreme obesityBody habitusHigher oddsNational Cardiovascular Data Registry ICD RegistryImplantable Cardioverter-Defibrillator RegistrySuccessful LV lead placementPatient body mass indexWorld Health Organization classificationBackgroundCardiac resynchronization therapyNormal weight patientsVentricular lead placementCRT-D therapyPatient body habitusHierarchical logistic regressionEligible patientsWeight patientsMultivariable adjustmentClinical characteristicsDefibrillator implantationBiventricular pacing
2017
Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Marzec LN, Peterson PN, Bao H, Curtis JP, Masoudi FA, Varosy PD, Bradley SM. Use of Cardiac Resynchronization Therapy Among Eligible Patients Receiving an Implantable Cardioverter Defibrillator: Insights From the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. JAMA Cardiology 2017, 2: 561-565. PMID: 28122073, PMCID: PMC5814986, DOI: 10.1001/jamacardio.2016.5388.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationBlack or African AmericanBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesCerebrovascular DisordersCohort StudiesComorbidityDefibrillators, ImplantableDiabetes MellitusEthnicityFemaleHealth Facility SizeHeart FailureHospitalsHospitals, TeachingHumansHypertensionInsurance, HealthLung DiseasesMaleMedicaidMedicareMiddle AgedMortalityMyocardial IschemiaPractice Patterns, Physicians'RegistriesRegression AnalysisRetrospective StudiesUnited StatesWhite PeopleConceptsUse of CRTCardiac resynchronization therapyCRT-D useImplantable cardioverter defibrillatorGuideline-eligible patientsDevice implantationEligible patientsResynchronization therapyCardioverter defibrillatorNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryNational Cardiovascular Data Registry ICD RegistryHeart failure-related eventsImplantable Cardioverter-Defibrillator RegistryCRT-D groupMulticenter retrospective cohortRisk-standardized ratesHospital-level variationCRT-D devicesHierarchical multivariable modelNonprivate insuranceRetrospective cohortSelect patientsICD RegistryGuideline recommendationsICD placement
2014
Primary Prevention Implantable Cardioverter-Defibrillators and Survival in Older Women
Zeitler EP, Hellkamp AS, Fonarow GC, Hammill SC, Curtis LH, Hernandez AF, Al-Khalidi HR, Curtis JP, Heidenreich PA, Anstrom KJ, Peterson ED, Mark DB, Hammill BG, Sanders GD, Al-Khatib SM. Primary Prevention Implantable Cardioverter-Defibrillators and Survival in Older Women. JACC Heart Failure 2014, 3: 159-167. PMID: 25543969, PMCID: PMC4461749, DOI: 10.1016/j.jchf.2014.09.006.Peer-Reviewed Original ResearchConceptsPrimary prevention implantable cardioverter defibrillatorsImplantable cardioverter defibrillatorHeart failureCardioverter defibrillatorOlder womenNational Cardiovascular Data Registry ICD RegistryLeft ventricular dysfunctionSignificant survival benefitSurvival of womenYears of ageMedicare claims databaseEligible patientsCause mortalityPrimary endpointVentricular dysfunctionSurvival benefitICD RegistryClaims databaseHeart failure databaseLonger survivalClinical trialsPropensity score methodsPatientsWomenSurvival
2013
Temporal Trends in Quality of Care Among Recipients of Implantable Cardioverter-Defibrillators
Dodson JA, Lampert R, Wang Y, Hammill SC, Varosy P, Curtis JP. Temporal Trends in Quality of Care Among Recipients of Implantable Cardioverter-Defibrillators. Circulation 2013, 129: 580-586. PMID: 24192798, PMCID: PMC3946506, DOI: 10.1161/circulationaha.113.003747.Peer-Reviewed Original ResearchConceptsOptimal medical therapyCardiac resynchronization therapyAdverse eventsEligible patientsQuality of careICD RegistryPotential confoundersNew York Heart Association class III/IVClass III/IVAngiotensin-converting enzyme inhibitorAngiotensin receptor blockersVentricular ejection fractionNew ICD implantsImplantable cardioverter defibrillatorHierarchical logistic regressionCRT eligibilityReceptor blockersEjection fractionMedical therapyResynchronization therapyICD implantsObservational studyCardioverter defibrillatorΒ-blockersPatientsUse of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators
Akar JG, Bao H, Jones P, Wang Y, Chaudhry SI, Varosy P, Masoudi FA, Stein K, Saxon LA, Curtis JP. Use of Remote Monitoring of Newly Implanted Cardioverter-Defibrillators. Circulation 2013, 128: 2372-2383. PMID: 24043302, DOI: 10.1161/circulationaha.113.002481.Peer-Reviewed Original ResearchConceptsMedian odds ratioOdds ratioNational Cardiovascular Data Registry ICD RegistryRemote patient monitoringMultivariable logistic regressionHealth-related factorsImplanted cardioverter defibrillatorEligible patientsICD RegistryLack of enrollmentCurrent guidelinesCardioverter defibrillatorPatientsLogistic regressionLocal practice environmentMajor causeHealth insuranceSubsequent activationEnrollmentPractice environmentPatient monitoringPhysiciansActivationRPM systemSuccessful use
2004
Association Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction
Vitagliano G, Curtis JP, Concato J, Feinstein AR, Radford MJ, Krumholz HM. Association Between Functional Status and Use and Effectiveness of Beta‐Blocker Prophylaxis in Elderly Survivors of Acute Myocardial Infarction. Journal Of The American Geriatrics Society 2004, 52: 495-501. PMID: 15066062, DOI: 10.1111/j.1532-5415.2004.52153.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute DiseaseAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overCross-Sectional StudiesDrug PrescriptionsDrug UtilizationFemaleGeriatric AssessmentHumansLogistic ModelsMaleMultivariate AnalysisMyocardial InfarctionPatient DischargePatient SelectionPractice Patterns, Physicians'Proportional Hazards ModelsRetrospective StudiesSurvival AnalysisTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionHospital dischargeFunctional impairmentElderly patientsMyocardial infarctionAcute myocardial infarction survivorsBeta-blocker prescriptionBeta-blocker prophylaxisBeta-blocker treatmentRetrospective cohort studySimilar survival benefitMain outcome measuresMyocardial infarction survivorsAcute care hospitalsEligible patientsCohort studySurvival benefitCare hospitalFunctional statusNational cohortInfarction survivorsOutcome measuresElderly survivorsPatientsCognitive impairment