2024
Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions.
Chen G, Hwang E, Leonard C, Cohen J. Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions. PLOS ONE 2024, 19: e0310498. PMID: 39536018, PMCID: PMC11560005, DOI: 10.1371/journal.pone.0310498.Peer-Reviewed Original ResearchConceptsPM2.5 concentrationsAmbient air pollutionUs Research ProgramAir pollutionCross-sectional studyAnnual PM2.5 concentrationCohort of American adultsPM2.5 exposureParticulate matterPM2.5Odds of eczemaPrevalence of eczemaAssociated with eczemaRisk of eczemaEnvironmental hazardsAtopic comorbiditiesPollutionSmoking statusTargeted interventionsZip codesAmerican adultsLogistic regressionAmerican cohortDemographic factorsOne-way analysis of variance
2023
Obsessive–compulsive disorder among patients with atopic dermatitis: a case–control study in the All of Us research program
Chen G, Fan R, Leasure A, Levey D, Damsky W, Cohen J. Obsessive–compulsive disorder among patients with atopic dermatitis: a case–control study in the All of Us research program. Archives Of Dermatological Research 2023, 316: 11. PMID: 38038754, DOI: 10.1007/s00403-023-02767-3.Peer-Reviewed Original ResearchMachine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis
Murphy M, Hwang E, Singh K, Lee T, Cohen J, Damsky W. Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis. British Journal Of Dermatology 2023, 190: 132-134. PMID: 37818837, DOI: 10.1093/bjd/ljad389.Peer-Reviewed Original ResearchBaseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis
Singh K, Valido K, Swallow M, Okifo K, Wang A, Cohen J, Damsky W. Baseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis. Journal Of The American Academy Of Dermatology 2023, 88: 1094-1100. PMID: 36780951, DOI: 10.1016/j.jaad.2022.12.052.Peer-Reviewed Original ResearchConceptsEczematous dermatitisHistologic featuresTreatment selectionType 1Type 3 inflammationInflammatory skin diseaseCertain histologic featuresSitu hybridization correlatesClinical responseNonresponder groupCytokine profileCytokine stainingAtopic dermatitisCytokine RNAEczematous disordersSitu hybridizationDupilumabIL13 expressionSkin diseasesType 2PatientsDermatitisNonrespondersMolecular heterogeneityImproved responseThe effect of baseline eczema or psoriasis on the morphology of cutaneous immune-related adverse events due to immune checkpoint inhibitor therapy
Belzer A, Mortlock R, Pach J, Cohen J, Leventhal J. The effect of baseline eczema or psoriasis on the morphology of cutaneous immune-related adverse events due to immune checkpoint inhibitor therapy. Journal Of The American Academy Of Dermatology 2023, 88: 1198-1200. PMID: 36634749, PMCID: PMC10121758, DOI: 10.1016/j.jaad.2023.01.002.Peer-Reviewed Original Research
2022
Comment on “Diagnostic testing of eczematous dermatitis with incomplete response to dupilumab”
Cohen JM, Damsky W, Girardi M. Comment on “Diagnostic testing of eczematous dermatitis with incomplete response to dupilumab”. Journal Of The American Academy Of Dermatology 2022, 87: e241-e242. PMID: 35933070, DOI: 10.1016/j.jaad.2022.05.069.Peer-Reviewed Original ResearchPrevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research program
Leasure AC, Cohen JM. Prevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research program. Archives Of Dermatological Research 2022, 315: 999-1001. PMID: 35147780, DOI: 10.1007/s00403-022-02328-0.Peer-Reviewed Original ResearchConceptsPrevalence of eczemaEczema casesEczema prevalenceConfidence intervalsCross-sectional studyEHR dataAvailable EHR dataCross-sectional analysisRace/ethnicityFemale predominanceSignificant morbidityUS adultsAge 75Average ageEczemaUs Research ProgramAdult cohortHispanic participantsPrevalenceAge 18US studiesAgeWhite participantsAdultsParticipants
2020
Psoriasis With Eczematous Features: A Retrospective Clinicopathologic Study.
Noorily AR, Criscito MC, Cohen JM, Brinster NK. Psoriasis With Eczematous Features: A Retrospective Clinicopathologic Study. American Journal Of Dermatopathology 2020, 43: 112-118. PMID: 32618707, DOI: 10.1097/dad.0000000000001711.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, CutaneousAdministration, OralAdultAgedAged, 80 and overBiological ProductsBiopsyDatabases, FactualDermatitis, Allergic ContactEczemaFemaleGlucocorticoidsHumansImmunosuppressive AgentsMaleMiddle AgedPredictive Value of TestsPsoriasisRemission InductionRetrospective StudiesSkinTreatment OutcomeYoung AdultConceptsAllergic contact dermatitisPsoriasis vulgarisClinical characteristicsHistopathological featuresEczematous changesDiagnostic workupSuccessful treatmentContact dermatitisOutcomes of patientsPercent of patientsHalf of patientsRetrospective chart reviewFeatures of psoriasisRetrospective clinicopathologic studyEczematous dermatosesEczematous featuresChart reviewClinicopathologic studyMost patientsSystemic therapyTopical glucocorticoidsHistopathologic featuresChallenging diagnosisClinicopathologic correlationTreatment modalities