2024
Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisBipolar disorder among individuals with atopic dermatitis: A case-control study in the All of Us Research Program
Wride A, Chen G, Fan R, Leasure A, Jones S, Levey D, Damsky W, Cohen J. Bipolar disorder among individuals with atopic dermatitis: A case-control study in the All of Us Research Program. Clinical And Experimental Dermatology 2024, llae451. PMID: 39425681, DOI: 10.1093/ced/llae451.Peer-Reviewed Original ResearchAssociation between atopic dermatitis and eating disorders: a cross-sectional study in the All of Us Research Program
Chen G, Xu S, White M, Cohen J. Association between atopic dermatitis and eating disorders: a cross-sectional study in the All of Us Research Program. British Journal Of Dermatology 2024, 190: 925-927. PMID: 38466772, DOI: 10.1093/bjd/ljae103.Peer-Reviewed Original ResearchComorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program
Kamal K, Xiang D, Young K, Mostaghimi A, Barbieri J, Cohen J, Theodosakis N. Comorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program. Archives Of Dermatological Research 2024, 316: 79. PMID: 38252292, DOI: 10.1007/s00403-023-02803-2.Peer-Reviewed Original ResearchConceptsAlcohol use disorderComorbid psychiatric diseaseUse disorderPsychiatric diseasesRates of alcohol use disordersOdds of alcohol use disordersContribution of depressionPhysical health effectsComorbid depressionMediation analysisAnxietyDepressionDisordersDermatological diseasesCase-control studyPigmentary skin disorderMultivariate logistic regressionHidradenitis suppurativaAtopic dermatitisSkin disordersPigmentary disordersCase-control modelIncreased oddsPatientsUs Research Program
2023
Association between atopic dermatitis and hypertension and hyperlipidemia: A cross-sectional study in the All of Us Research Program
Craver A, Chen G, Cohen J. Association between atopic dermatitis and hypertension and hyperlipidemia: A cross-sectional study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 90: 819-821. PMID: 38008413, DOI: 10.1016/j.jaad.2023.11.026.Peer-Reviewed Original ResearchAssociation between atopic dermatitis and inflammatory bowel disease among US adults in the All of Us Research Program
Joel M, Damsky W, Cohen J, Wride M. Association between atopic dermatitis and inflammatory bowel disease among US adults in the All of Us Research Program. Clinical And Experimental Dermatology 2023, 49: 390-392. PMID: 37967342, PMCID: PMC10957220, DOI: 10.1093/ced/llad397.Peer-Reviewed Original ResearchMachine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis
Murphy M, Hwang E, Singh K, Lee T, Cohen J, Damsky W. Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis. British Journal Of Dermatology 2023, 190: 132-134. PMID: 37818837, DOI: 10.1093/bjd/ljad389.Peer-Reviewed Original Research44140 Obsessive-Compulsive Disorder Among Patients with Atopic Dermatitis: A Case-Control Study in the All of Us Research Program
Chen G, Fan R, Leasure A, Damsky W, Cohen J. 44140 Obsessive-Compulsive Disorder Among Patients with Atopic Dermatitis: A Case-Control Study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 89: ab69. DOI: 10.1016/j.jaad.2023.07.279.Peer-Reviewed Original ResearchAssessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology
Mortlock R, Ma E, Cohen J, Damsky W. Assessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology. Journal Of Investigative Dermatology 2023, 143: 1412-1422. PMID: 37341663, PMCID: PMC10830170, DOI: 10.1016/j.jid.2023.04.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAtopic dermatitisSkin diseasesInflammatory skin diseaseInflammatory skin conditionImmunologic biomarkersImmune biomarkersPersonalized medicineInflammatory dermatosesImmunologic approachesTherapy selectionSkin conditionsSingle-cell RNA sequencingMolecular profilingBiomarkersTissue stainingPsoriasisDermatitisDiseaseDermatologyRNA sequencingMedicineCurettageDermatosesTherapyPersonalized classificationAssociation between atopic dermatitis and eosinophilic esophagitis: a cross‐sectional study in the All of Us Research Program
Chen G, Cohen J. Association between atopic dermatitis and eosinophilic esophagitis: a cross‐sectional study in the All of Us Research Program. International Journal Of Dermatology 2023, 62: e556-e557. PMID: 37081803, PMCID: PMC10524237, DOI: 10.1111/ijd.16690.Peer-Reviewed Original ResearchAssociation of atopic dermatitis with schizophrenia and schizoaffective disorder: A case-control study in the All of Us Research Program
Fan R, Chen G, Leasure A, Johnson M, Damsky W, Cohen J. Association of atopic dermatitis with schizophrenia and schizoaffective disorder: A case-control study in the All of Us Research Program. 2023 DOI: 10.21203/rs.3.rs-2782847/v1.Peer-Reviewed Original ResearchAtopic dermatitisSchizoaffective disorderRace/ethnicityUs Research ProgramMental health comorbiditiesElectronic health record dataCase-control studyMajor depressive disorderHealth record dataDiagnosis of schizophreniaHealth comorbiditiesMultivariable analysisPathophysiologic mechanismsSmoking statusDepressive disorderAD casesSchizophreniaAnxiety disordersComparing RatesDisordersRecord dataNational InstituteFurther studiesPatientsDermatitisBaseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis
Singh K, Valido K, Swallow M, Okifo K, Wang A, Cohen J, Damsky W. Baseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis. Journal Of The American Academy Of Dermatology 2023, 88: 1094-1100. PMID: 36780951, DOI: 10.1016/j.jaad.2022.12.052.Peer-Reviewed Original ResearchConceptsEczematous dermatitisHistologic featuresTreatment selectionType 1Type 3 inflammationInflammatory skin diseaseCertain histologic featuresSitu hybridization correlatesClinical responseNonresponder groupCytokine profileCytokine stainingAtopic dermatitisCytokine RNAEczematous disordersSitu hybridizationDupilumabIL13 expressionSkin diseasesType 2PatientsDermatitisNonrespondersMolecular heterogeneityImproved response
2022
The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program
Hodelin C, Fan R, Damsky W, Cohen J. The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program. International Journal Of Dermatology 2022, 62: e430-e431. PMID: 36468789, DOI: 10.1111/ijd.16544.Peer-Reviewed Original ResearchMigraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme
Fan R, Leasure A, Damsky W, Cohen J. Migraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme. Clinical And Experimental Dermatology 2022, 48: 24-26. PMID: 36669173, DOI: 10.1093/ced/llac004.Peer-Reviewed Original ResearchAlcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research program
Fan R, Leasure AC, Damsky W, Cohen JM. Alcohol use disorder among adults with atopic dermatitis: A case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2022, 87: 1378-1380. PMID: 36152694, DOI: 10.1016/j.jaad.2022.09.015.Peer-Reviewed Original Research187 Mental health comorbidities and alcohol use disorder in atopic dermatitis: A case-control study in the All of Us research program
Fan R, Leasure A, Damsky W, Cohen J. 187 Mental health comorbidities and alcohol use disorder in atopic dermatitis: A case-control study in the All of Us research program. Journal Of Investigative Dermatology 2022, 142: s32. DOI: 10.1016/j.jid.2022.05.194.Peer-Reviewed Original ResearchVaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide.
Fan R, Cohen JM. Vaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide. The Yale Journal Of Biology And Medicine 2022, 95: 249-255. PMID: 35782480, PMCID: PMC9235258.Peer-Reviewed Original ResearchConceptsAtopic dermatitis patientsBiologic therapyVaccination recommendationsDermatitis patientsTreatment of psoriasisNovel biologic therapiesIL-17IL-23Atopic dermatitisIL-12/23Vaccine administrationClinical dataHealthcare providersAvailable guidelinesPsoriasisTherapyUnique considerationsPatientsPractical guideVaccinationDermatitisTNFαInfectionDermatologistsAdministrationAssociation of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control study
Fan R, Leasure AC, Damsky W, Cohen JM. Association of atopic dermatitis with attention-deficit hyperactivity disorder among US adults in the “All of Us” research program: A case-control study. Journal Of The American Academy Of Dermatology 2022, 87: 691-692. PMID: 35283246, DOI: 10.1016/j.jaad.2022.03.014.Peer-Reviewed Original Research
2021
Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program
Fan R, Leasure AC, Damsky W, Cohen JM. Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program. JAAD International 2021, 6: 77-81. PMID: 34977817, PMCID: PMC8712258, DOI: 10.1016/j.jdin.2021.12.007.Peer-Reviewed Original ResearchCOVID-19 infectionCase-control studyMultivariable analysisAD patientsAtopic dermatitis patientsCOVID-19 outcomesCOVID-19COVID-19 diagnosisElectronic health recordsCommon comorbiditiesAtopic dermatitisDermatitis patientsAD severityCOVID-19 casesUS cohortRisk factorsClinical dataAD casesUs Research ProgramComorbiditiesDiverse cohortPatientsInfectionCohortHealth recordsCytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis
Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.Peer-Reviewed Original ResearchAtopic dermatitisAtopic dermatitis casesInflammatory skin diseaseInflammatory skin disorderSubset of casesSitu hybridizationCytokine RNARoutine biopsyCytokine expressionPredominant cytokinePsoriasis casesCytokine targetsTreatment selectionDermatitis casesSkin disordersPsoriasis biomarkersSkin diseasesIndividual cytokinesIndividualized evaluationPsoriasisBiopsyBulk RNA sequencingCytokinesMolecular phenotypingPatients