2016
Clinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit
Cha J, DeDora D, Nedic S, Ide J, Greenberg T, Hajcak G, Mujica-Parodi L. Clinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit. Journal Of Neuroscience 2016, 36: 4708-4718. PMID: 27122030, PMCID: PMC6601720, DOI: 10.1523/jneurosci.1092-15.2016.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusVentromedial prefrontal cortexFrontal gyrusPrefrontal-limbic regionsAnxious individualsStimulus meaningNeurobiological responsesPrefrontal cortexFear generalization taskPrefrontal-limbic circuitsPrefrontal-limbic connectivityEmotion regulationAffective neurosciencePrefrontal-limbic systemGeneralization taskPerceptual similaritySimilarity gradientsPrefrontal regionsFMRI studyClinical anxietyAnxiety spectrumAnxiety severityVmPFCFunctional connectivityGyrus
2015
Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task
Hu S, Ide JS, Zhang S, Sinha R, Li CS. Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task. NeuroImage Clinical 2015, 8: 39-50. PMID: 26106526, PMCID: PMC4473266, DOI: 10.1016/j.nicl.2015.03.008.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeHealthy control individualsConflict anticipationAlcohol dependenceCognitive controlProactive controlSignal taskSequential effectsModel-based fMRI studyAlcohol consumptionStop signalPre-supplementary motor areaBilateral inferior parietal cortexPerigenual anterior cingulate cortexSignificant sequential effectInferior parietal cortexSignal reaction timeWhole-brain responsesAnterior cingulate cortexRecent alcohol consumptionNeural correlatesFMRI studyNeural markersMotor areaTrial onset