1998
ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA
KUNDU S, KIM I, ZELNER D, JANULIS L, GOODWIN S, ENGEL J, LEE C. ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA. Journal Of Urology 1998, 160: 1883-1888. PMID: 9783979, DOI: 10.1016/s0022-5347(01)62437-6.Peer-Reviewed Original ResearchConceptsTGF-beta1 productionRenca cellsTGF-beta sensitivityRenal carcinoma cell linesCarcinoma cell linesInhibitory effectEndogenous TGF-beta1 productionWild-type Renca cellsCell linesTGF-beta receptor expressionTbetaR-II mRNAAggressive growth patternGrowth factor beta type II receptorTGF-beta1 mRNATGF-beta insensitivityPlasminogen activator inhibitorTbetaR-I mRNAType II receptorAbsence of expressionReceptor expressionTbetaR-IIII receptorsActivator inhibitorAggressive growthThymidine incorporationABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA
KUNDU S, KIM I, ZELNER D, JANULIS L, GOODWIN S, ENGEL J, LEE C. ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA. Journal Of Urology 1998, 160: 1883-1888.. DOI: 10.1097/00005392-199811000-00077.Peer-Reviewed Original ResearchT beta RRenca cellsTGF-beta sensitivityRenal carcinoma cell linesCarcinoma cell linesBeta RInhibitory effectWild-type Renca cellsCell linesTGF-beta receptor expressionAggressive growth patternGrowth factor beta type II receptorTGF-beta insensitivityPlasminogen activator inhibitorType II receptorAbsence of expressionReceptor expressionII receptorsActivator inhibitorAggressive growthTumor cellsThymidine incorporationRT-PCRCancer cellsReceptors
1996
Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.
Kim I, Ahn H, Zelner D, Shaw J, Sensibar J, Kim J, Kato M, Lee C. Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells. Cancer Research 1996, 56: 44-8. PMID: 8548772.Peer-Reviewed Original ResearchConceptsProstate cancer cell linesLNCaP cellsProstate cancer cellsType I receptorT beta RCancer cell linesI geneDU145 cellsGenetic changesTGF-beta receptor type III receptorTGF-beta receptor expressionGrowth factor beta 1Beta RCancer cellsHuman prostate cancer cellsProliferation of PC3TGF-beta signalsBlot analysisReceptor type IICell linesDose-dependent mannerSouthern blot analysisType I geneType II receptor