1997
Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides)
Quirós P, Jones G, Kacinski B, Braverman I, Heald P, Edelson R, Wilson L. Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-A light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides). International Journal Of Radiation Oncology • Biology • Physics 1997, 38: 1027-1035. PMID: 9276369, DOI: 10.1016/s0360-3016(97)00127-2.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDisease-free survivalT2 patientsCrude relapse rateAdjuvant therapyOverall survivalElectron beam therapyRelapse rateEntire cohortMedian disease-free survivalCutaneous T-cell lymphomaBeam therapySalvage of recurrencesAdjuvant systemic therapyEarly-stage patientsManagement of patientsT-cell lymphomaTopical nitrogen mustardDays/weekCombination of therapiesGy/dayTreatments/weekPUVA patientsMedian followSalvage therapy
1996
Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma
Wilson L, Quiros P, Kolenik S, Heald P, Braverman I, Edelson R, Kacinski B. Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma. Journal Of The American Academy Of Dermatology 1996, 35: 69-73. PMID: 8682967, DOI: 10.1016/s0190-9622(96)90499-5.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaRecurrent cutaneous T-cell lymphomaComplete responseT-cell lymphomaElectron beam therapySecond courseMedian disease-free intervalThird courseAdditional coursesBeam therapyDisease-free intervalTreatment of patientsAcceptable risk profileForm of therapyMedian doseMedian survivalMild erythemaPatientsInitial courseTherapyVariety of modalitiesRisk profileEntire groupLocalized radiation
1995
Systemic chemotherapy and extracorporeal photochemotherapy for T3 and T4 cutaneous T-cell lymphoma patients who have achieved a complete response to total skin electron beam therapy
Wilson L, Licata A, Braverman I, Edelson R, Heald P, Feldman A, Kacinski B. Systemic chemotherapy and extracorporeal photochemotherapy for T3 and T4 cutaneous T-cell lymphoma patients who have achieved a complete response to total skin electron beam therapy. International Journal Of Radiation Oncology • Biology • Physics 1995, 32: 987-995. PMID: 7607973, DOI: 10.1016/0360-3016(95)00073-8.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyDoxorubicin/cyclophosphamideCutaneous T-cell lymphoma patientsAdjuvant doxorubicin/cyclophosphamideT-cell lymphoma patientsExtracorporeal photochemotherapyComplete responseOverall survivalAdjuvant therapyElectron beam therapyAdjuvant regimenFree survivalCTCL patientsLymphoma patientsBeam therapyAddition of chemotherapyAdvanced stage CTCLClinical complete responseSystemic adjuvant therapyGood partial responseSignificant survival benefitBetter overall survivalRelapse-free survivalSoles of feetNontoxic regimenMalignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation.
Licata AG, Wilson LD, Braverman IM, Feldman AM, Kacinski BM. Malignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation. JAMA Dermatology 1995, 131: 432-5. PMID: 7726585, DOI: 10.1001/archderm.131.4.432.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaT-cell lymphomaSquamous cell carcinomaBasal cell carcinomaElectron beam therapyAdditional radiation therapyCell carcinomaCutaneous malignanciesOral psoralenAdditional therapyMalignant melanomaRadiation therapyBeam therapyTotal skin electron beam radiationFurther radiation therapyGroup of patientsNonmelanoma skin cancerAnecdotal case reportsPrevious large studiesTopical mechlorethamineHydrochloride therapyCase reportPatientsCarcinoma
1994
Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients
Petzelbauer P, Pober J, Keh A, Braverman I. Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients. Journal Of Investigative Dermatology 1994, 103: 300-305. PMID: 7521374, DOI: 10.1111/1523-1747.ep12394720.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Endothelial leukocyte adhesion molecule-1Lesional skinAdhesion molecule-1Psoriatic patientsEndothelial cellsUninvolved skinPerilesional skinMolecule-1Dermal microvasculatureCapillary loopsCell adhesion molecule-1Perivascular inflammatory infiltratesLeukocyte adhesion molecule-1VCAM-1 expressionTumor necrosis factorEndothelial adhesion moleculesMicrovascular endothelial cellsEndothelial cell expressionVenular endothelial cellsInflammatory infiltrateEpidermal involvementPsoriatic plaquesSuperficial plexusNecrosis factorSpatial Heterogeneity in Normal Skin Perfusion Recorded with Laser Doppler Imaging and Flowmetry
Wardell K, Braverman I, Silverman D, Nilsson G. Spatial Heterogeneity in Normal Skin Perfusion Recorded with Laser Doppler Imaging and Flowmetry. Microvascular Research 1994, 48: 26-38. PMID: 7990721, DOI: 10.1006/mvre.1994.1036.Peer-Reviewed Original ResearchImpact of non-CTCL dermatologic diagnoses and adjuvant therapies on cutaneous T-cell lymphoma patients treated with total skin electron beam radiation therapy
Wilson L, Cooper D, Goodrich A, Friedman N, Feldman A, Braverman I, Kacinski B. Impact of non-CTCL dermatologic diagnoses and adjuvant therapies on cutaneous T-cell lymphoma patients treated with total skin electron beam radiation therapy. International Journal Of Radiation Oncology • Biology • Physics 1994, 28: 829-837. PMID: 8138435, DOI: 10.1016/0360-3016(94)90102-3.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapySystemic adjuvant therapyRelapse-free survivalDoxorubicin/cyclophosphamide chemotherapyShorter relapse-free survivalElectron beam therapyAdjuvant therapyDermatologic diagnosesBeam therapyCyclophosphamide chemotherapyFollicular mucinosisOverall survivalT2 patientsExtracorporeal photopheresisLymphomatoid papulosisCutaneous relapseTotal skin electron beam radiation therapyCutaneous T-cell lymphoma patientsT-cell lymphoma patientsBetter relapse-free survivalClinical complete responseCohort of patientsElectron beam radiation therapyBeam radiation therapyAdjuvant chemotherapy
1993
Transformation in Cutaneous T-Cell Lymphoma
Braverman I, Redfern C. Transformation in Cutaneous T-Cell Lymphoma. Journal Of Investigative Dermatology 1993, 101: 249-251. PMID: 8370959, DOI: 10.1111/1523-1747.ep12365124.Peer-Reviewed Original ResearchCyclosporine treatment of refractory T‐cell lymphomas
Cooper D, Braverman I, Sarris A, Durivage H, Saidman B, Davis C, Hait W. Cyclosporine treatment of refractory T‐cell lymphomas. Cancer 1993, 71: 2335-2341. PMID: 8453556, DOI: 10.1002/1097-0142(19930401)71:7<2335::aid-cncr2820710727>3.0.co;2-d.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCyclosporineFemaleHumansLymphoma, T-Cell, CutaneousLymphoma, T-Cell, PeripheralMaleMiddle AgedConceptsCutaneous T-cell lymphomaPeripheral T-cell lymphomaRefractory T-cell lymphomaT-cell lymphomaMost patientsDisease progressionReinstitution of therapySubsequent graft rejectionPhase II trialT cell expansionT-cell neoplasmsTranscription of cytokinesCyclosporine treatmentClinical remissionII trialPrevious therapyRecurrent diseaseCsA administrationGraft rejectionRenal toxicityAntiinflammatory effectsRapid recurrenceTransplanted organsInterleukin-2Radiation therapy
1992
Synchronous vasomotion in the human cutaneous microvasculature provides evidence for central modulation
Schechner J, Braverman I. Synchronous vasomotion in the human cutaneous microvasculature provides evidence for central modulation. Microvascular Research 1992, 44: 27-32. PMID: 1640877, DOI: 10.1016/0026-2862(92)90099-b.Peer-Reviewed Original ResearchTopographic mapping of the cutaneous microcirculation using two outputs of laser-Doppler flowmetry: Flux and the concentration of moving blood cells
Braverman I, Schechner J, Silverman D, Keh-Yen A. Topographic mapping of the cutaneous microcirculation using two outputs of laser-Doppler flowmetry: Flux and the concentration of moving blood cells. Microvascular Research 1992, 44: 33-48. PMID: 1640878, DOI: 10.1016/0026-2862(92)90100-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiopsyCell MovementErythrocytesHumansLasersMaleMicrocirculationMiddle AgedSkinVideo RecordingConceptsUpper plexusLaser Doppler flowmetryCutaneous microcirculationTrephine biopsyVascular unitAvascular zoneAscending arteriolesVascular patternMicrovascular areaPlexusBlood cellsUpper thirdFlexor forearmSerial sectionsLaser Doppler instrumentArteriolesForearmPeripheral partCMBCPhysiological studiesSubjectsCell outputBiopsyFlowmetryMicrocirculation
1991
The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis
Verga M, Braverman I. The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis. JAMA Dermatology 1991, 127: 1503-1510. PMID: 1929457, DOI: 10.1001/archderm.1991.01680090067006.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaT-cell lymphomaCTCL lesionsImmunohistologic analysisEarly-stage cutaneous T-cell lymphomaBenign inflammatory diseaseImmunohistologic patternsDR antibodiesHLA-DRBiopsy specimensInflammatory diseasesPsoriatic lesionsImmunoperoxidase techniquePsoriatic skinDermatitic lesionsExtensive stainingPsoriasisNormal skinDermatitisLesionsPatientsMonoclonal antibodiesEpidermal areaLymphomaAntibodies
1990
Ultrastructure and Three-Dimensional Organization of the Telangiectases of Hereditary Hemorrhagic Telangiectasia
Braverman I, Keh A, Jacobson B. Ultrastructure and Three-Dimensional Organization of the Telangiectases of Hereditary Hemorrhagic Telangiectasia. Journal Of Investigative Dermatology 1990, 95: 422-427. PMID: 2212727, DOI: 10.1111/1523-1747.ep12555569.Peer-Reviewed Original Research
1989
Skin changes in menopause
Bolognia J, Braverman I, Rousseau M, Sarrel P. Skin changes in menopause. Maturitas 1989, 11: 295-304. PMID: 2693917, DOI: 10.1016/0378-5122(89)90026-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMenopausal womenEstrogen replacement therapyElastic fibersAge-related ultrastructural changesSun-exposed skinSun-protected skinDermal elastic fibersCutaneous signsEstrogen deprivationPremature menopauseReplacement therapySkin changesSkin signsTreatment periodCystic spacesDegenerative changesGranular degenerationSymptomsUltrastructural changesWomenMenopauseSignificant differencesPatientsPremature agingSkinAngiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesionsElastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Clinics In Geriatric Medicine 1989, 5: 69-90. PMID: 2646003, DOI: 10.1016/s0749-0690(18)30696-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesClinical featuresDiabetic patientsVeil cellsJuvenile diabetesDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processLikely correlateDiabetesPatientsAtrophy
1986
Familial multiple lipomatosis Report of a case and a review of the literature
Leffell D, Braverman I. Familial multiple lipomatosis Report of a case and a review of the literature. Journal Of The American Academy Of Dermatology 1986, 15: 275-279. PMID: 3745530, DOI: 10.1016/s0190-9622(86)70166-7.Peer-Reviewed Original ResearchElastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Dermatologic Clinics 1986, 4: 391-405. PMID: 3521985, DOI: 10.1016/s0733-8635(18)30802-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesDiabetic patientsJuvenile diabeticsClinical featuresVeil cellsDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processDiabeticsLikely correlatePatientsAtrophyThree-Dimensional Reconstruction of Endothelial Cell Gaps in Psoriatic Vessels and Their Morphologic Identity with Gaps Produced by the Intradermal Injections of Histamine
Braverman I, Keh-Yen A. Three-Dimensional Reconstruction of Endothelial Cell Gaps in Psoriatic Vessels and Their Morphologic Identity with Gaps Produced by the Intradermal Injections of Histamine. Journal Of Investigative Dermatology 1986, 86: 577-581. PMID: 3745967, DOI: 10.1111/1523-1747.ep12355222.Peer-Reviewed Original Research
1985
The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate
Braverman I, Sibley J. The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate. Journal Of Investigative Dermatology 1985, 85: 584-586. PMID: 4067330, DOI: 10.1111/1523-1747.ep12283604.Peer-Reviewed Original ResearchConceptsOral methotrexateTopical steroidsLabeling indexPsoriatic epidermisInitial clinical improvementPlastic wrap occlusionTopical steroid therapyBasal cellsLack of responseGoeckerman treatmentSteroid therapyClinical relapseClinical improvementPsoriatic patientsPsoriatic plaquesSuccessful therapyDermal capillariesCapillary ultrastructureMethotrexateModerate acanthosisCapillary loopsSteroidsDermal papillaTherapyMicrovessels