2020
Distinct vasculotropic versus osteotropic features of S. agalactiae versus S. aureus implant‐associated bone infection in mice
Masters EA, Hao SP, Kenney HM, Morita Y, Galloway CA, de Mesy Bentley K, Ricciardi BF, Boyce BF, Schwarz EM, Oh I. Distinct vasculotropic versus osteotropic features of S. agalactiae versus S. aureus implant‐associated bone infection in mice. Journal Of Orthopaedic Research® 2020, 39: 389-401. PMID: 33336806, PMCID: PMC7882123, DOI: 10.1002/jor.24962.Peer-Reviewed Original ResearchConceptsS. aureus osteomyelitisBone infectionS. agalactiaeAnimal modelsS. aureus bone infectionImplant looseningSoft tissueImplant-associated osteomyelitisQuantitative animal modelCortical boneAdjacent soft tissuesGroup B streptococciS. aureusSeptic implant looseningS. agalactiae infectionAssessment of miceS. aureus virulenceGreater body weightDevastating complicationClinical featuresAbscess formationLocal inflammationAggressive osteolysisLess osteolysisPreclinical modelsIntraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis
Brodell JD, Kozakiewicz LN, Hoffman SL, Oh I. Intraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis. Foot & Ankle International 2020, 42: 356-362. PMID: 33185116, DOI: 10.1177/1071100720962480.Peer-Reviewed Original ResearchConceptsDiabetic heel ulcersVancomycin powder applicationTotal calcanectomyVancomycin powderCalcaneal osteomyelitisHeel ulcersClinical outcomesRetrospective case-control studyLimb salvage rateOverall healing rateImproved clinical outcomesCase-control studyLocal tissue irritationMultidrug-resistant bacteriaVancomycin cohortWound complicationsClinical characteristicsOperative complicationsUlcer surgeryDiabetic patientsRevision amputationSalvage rateKnee amputationClinical benefitUnderwent revisionChopart Amputation: Questioning the Clinical Efficacy of a Long-standing Surgical Option for Diabetic Foot Infection.
Brodell JD, Ayers BC, Baumhauer JF, DiGiovanni BF, Flemister AS, Ketz JP, Oh I. Chopart Amputation: Questioning the Clinical Efficacy of a Long-standing Surgical Option for Diabetic Foot Infection. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 684-691. PMID: 32769724, DOI: 10.5435/jaaos-d-19-00757.Peer-Reviewed Original ResearchConceptsBaseline physical functionPROMIS Physical FunctionDiabetic foot infectionsPostoperative wound complicationsChopart amputationRevision amputationFoot infectionsWound complicationsPhysical functionWound healingOutcomes Measurement Information System (PROMIS) instrumentsPROMIS physical function scoresPhysical function scoresPatient-reported outcomesJudicious patient selectionExtent of infectionPostoperative complicationsTotal patientsCase seriesClinical outcomesKnee amputationPain interferencePatient selectionSurgical optionsTendon transfer
2019
What Is the Best Method to Differentiate Acute Charcot Foot From Acute Infection?
Heidari N, Oh I, Li Y, Vris A, Kwok I, Charalambous A, Rogero R. What Is the Best Method to Differentiate Acute Charcot Foot From Acute Infection? Foot & Ankle International 2019, 40: 39s-42s. PMID: 31322932, DOI: 10.1177/1071100719859892.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingCharcot neuroarthropathyPresence of neuropathyAcute Charcot footAcute Charcot neuroarthropathyMultiple diagnostic criteriaLikelihood of infectionCharcot footAcute infectionPhysical examinationHistologic examinationDiagnostic criteriaUnclear casesResonance imagingSkin woundsInfectionBone specimensLaboratory testingExaminationNeuroarthropathyNeuropathyOsteomyelitisScintigraphyErythema
2018
Chronic Osteomyelitis with Staphylococcus aureus Deformation in Submicron Canaliculi of Osteocytes
de Mesy Bentley KL, MacDonald A, Schwarz EM, Oh I. Chronic Osteomyelitis with Staphylococcus aureus Deformation in Submicron Canaliculi of Osteocytes. JBJS Case Connector 2018, 8: e8. PMID: 29443819, PMCID: PMC6681818, DOI: 10.2106/jbjs.cc.17.00154.Peer-Reviewed Original Research