2020
Adjuvant antibiotic‐loaded bone cement: Concerns with current use and research to make it work
Schwarz EM, McLaren AC, Sculco TP, Brause B, Bostrom M, Kates SL, Parvizi J, Alt V, Arnold WV, Carli A, Chen AF, Choe H, Coraça‐Huber D, Cross M, Ghert M, Hickok N, Jennings JA, Joshi M, Metsemakers W, Ninomiya M, Nishitani K, Oh I, Padgett D, Ricciardi B, Saeed K, Sendi P, Springer B, Stoodley P, Wenke JC, Workgroup H. Adjuvant antibiotic‐loaded bone cement: Concerns with current use and research to make it work. Journal Of Orthopaedic Research® 2020, 39: 227-239. PMID: 31997412, PMCID: PMC7390691, DOI: 10.1002/jor.24616.Peer-Reviewed Original ResearchConceptsAntibiotic-loaded bone cementMusculoskeletal infectionsLevel 1 evidenceRoutine laboratory testingMinimum biofilm eradication concentrationBone cementBiofilm eradication concentrationALBC useBiofilm-associated bacteriaOrthopedic infectionsClinical relevanceClinical practiceDrug AdministrationDrug susceptibilityLocal deliveryEradication concentrationInfectionAntibiotic resistanceCurrent useEfficacyVivo biofilmsLaboratory testingMicrobial colonizationPropose areasSubstantial lack
2019
What Is the Best Method to Differentiate Acute Charcot Foot From Acute Infection?
Heidari N, Oh I, Li Y, Vris A, Kwok I, Charalambous A, Rogero R. What Is the Best Method to Differentiate Acute Charcot Foot From Acute Infection? Foot & Ankle International 2019, 40: 39s-42s. PMID: 31322932, DOI: 10.1177/1071100719859892.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingCharcot neuroarthropathyPresence of neuropathyAcute Charcot footAcute Charcot neuroarthropathyMultiple diagnostic criteriaLikelihood of infectionCharcot footAcute infectionPhysical examinationHistologic examinationDiagnostic criteriaUnclear casesResonance imagingSkin woundsInfectionBone specimensLaboratory testingExaminationNeuroarthropathyNeuropathyOsteomyelitisScintigraphyErythema