2020
Intraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis
Brodell JD, Kozakiewicz LN, Hoffman SL, Oh I. Intraoperative Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers With Calcaneal Osteomyelitis. Foot & Ankle International 2020, 42: 356-362. PMID: 33185116, DOI: 10.1177/1071100720962480.Peer-Reviewed Original ResearchConceptsDiabetic heel ulcersVancomycin powder applicationTotal calcanectomyVancomycin powderCalcaneal osteomyelitisHeel ulcersClinical outcomesRetrospective case-control studyLimb salvage rateOverall healing rateImproved clinical outcomesCase-control studyLocal tissue irritationMultidrug-resistant bacteriaVancomycin cohortWound complicationsClinical characteristicsOperative complicationsUlcer surgeryDiabetic patientsRevision amputationSalvage rateKnee amputationClinical benefitUnderwent revisionIntra-surgical Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers with Calcaneal Osteomyelitis
Brodell J, Oh I. Intra-surgical Site Vancomycin Powder Application in Infected Diabetic Heel Ulcers with Calcaneal Osteomyelitis. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00144. PMCID: PMC8704756, DOI: 10.1177/2473011420s00144.Peer-Reviewed Original ResearchDiabetic heel ulcersVancomycin powder applicationVancomycin powderTotal calcanectomyVancomycin cohortHeel ulcersBone resection marginsCharleston Comorbidity IndexAnkle-brachial indexPeripheral arterial diseaseMulti-drug resistant bacteriaHigh rateASA classInfection surgeryIntrawound vancomycinPreoperative labsCalcaneal osteomyelitisComorbidity indexWound complicationsPatient demographicsSurgical complicationsSystemic antibioticsDiabetic patientsResection marginsRevision amputation
2019
Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing
Nichols AEC, Oh I, Loiselle AE. Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing. Journal Of Orthopaedic Research® 2019, 38: 13-22. PMID: 31166037, PMCID: PMC6893090, DOI: 10.1002/jor.24388.Peer-Reviewed Original ResearchConceptsTendon healingTendon functionType II diabetes mellitusPro-inflammatory environmentPre-clinical modelsNovel therapeutic strategiesPotential treatment approachRisk of ruptureHealth care challengesDiabetic tendinopathyDiabetes mellitusDiabetic patientsChronic tendinopathyAcute traumaTendon tearsImpaired restorationPathological progressionTendon repairTherapeutic strategiesTreatment approachesTendon structureUS populationCare challengesNative tendon structureHealing
2017
Clinical Application of Immunoassay for Identification of Staphylococcus aureus and Monitoring Treatment Response in Diabetic Foot Infection
Oh I, Smith B, Grier A, Gill S, Daiss J. Clinical Application of Immunoassay for Identification of Staphylococcus aureus and Monitoring Treatment Response in Diabetic Foot Infection. Foot & Ankle Orthopaedics 2017, 2: 2473011417s000065. DOI: 10.1177/2473011417s000065.Peer-Reviewed Original ResearchDiabetic foot infectionsFoot infectionsSA infectionsAntibiotic treatmentTreatment responseStaphylococcus aureusPathogenic activityAdequate prognostic informationNonspecific inflammatory markersIntravenous antibiotic treatmentWhole bloodMonitoring Treatment ResponseSigns of infectionStandard cultureAntibody-secreting cellsMicrobiome analysisFoot salvageSalvage therapySalvage treatmentSpecific diagnostic toolsInflammatory markersDiabetic patientsCounseling patientsClinical symptomsWeeks 0