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    Iris Isufi, MD

    Associate Professor of Medicine (Hematology)
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    Additional Titles

    Co-Director Adult CAR T-Cell Therapy Program, Hematology

    Co-Leader, Cellular Therapy Clinical Research Team, Yale Cancer Center

    Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center

    About

    Titles

    Associate Professor of Medicine (Hematology)

    Co-Director Adult CAR T-Cell Therapy Program, Hematology; Co-Leader, Cellular Therapy Clinical Research Team, Yale Cancer Center; Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center

    Appointments

    • Hematology

      Associate Professor on Term
      Primary
      Hematology

    Other Departments & Organizations

    Education & Training

    Fellowship
    Yale University School of Medicine (2011)
    Residency
    Albert Einstein College of Medicine/Montefiore Medical Center (2007)
    MD
    State University of New York at Stony Brook (2004)
    BA
    The College of Saint Rose, Albany, NY, 2000, Biology (2000)

    Research

    Overview

    Dr. Isufi's clinical work has been in the area of hematologic malignancies and autologous and allogeneic stem cell transplantation for these conditions. As part of the lymphoid malignancy and transplant teams, she developed a strong clinical interest in aggressive lymphomas. She has focused her efforts in treating patients with aggressive lymphomas as part of clinical trials and consolidating their response to treatment with either autologous or allogeneic transplant based on specifics of their disease. She has a research interest in early drug development in lymphoma, and has served as local PI for a variety of industry- and cooperative-group-sponsored lymphoma trials, including phase 1 trials.

    Medical Research Interests

    Bone Marrow Transplantation; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Graft vs Host Disease; Lymphoma; Transplantation Conditioning

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Iris Isufi's published research.

    Publications

    2024

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    Clinical Trials

    Current Trials

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    Academic Achievements & Community Involvement

    • honor

      ASCO/AACR Methods in Clinical Cancer Research Workshop Fellow, Vail, CO

      National AwardAACR
    • honor

      Outstanding House Officer in Internal Medicine Award

      Other AwardAlbert Einstein College of Medicine/Montefiore Medical Center
    • honor

      The Kijeon Yoo Award for Determination in Pursuit of a Medical Education

      Other AwardStony Brook University School of Medicine
    • honor

      Medical School Merit-Based Scholarship

      Other AwardStony Brook University School of Medicine

    Clinical Care

    Overview

    Iris Isufi, MD, is a hematologist who specializes in treating patients with lymphoma, multiple myeloma, and leukemia. Dr. Isufi provides care through treatments involving cellular therapy, which include CAR T-cell therapy and stem cell transplants. She is co-director of the CAR T-Cell Therapy Program for adults.

    “Cell therapies like CAR T-cell therapy are promising for diseases that haven’t responded to multiple types of treatment,” Dr. Isufi says. “It’s a recent development, but one that students in medical school are already learning about, and that’s very exciting.”

    The potential benefit of CAR T-cell therapy matters especially to Dr. Isufi, who grew up in Albania and sometimes accompanied her mother, a physician, on rounds at the hospital. “I saw challenges they [the doctors] were facing in trying to help people. Their determination inspired me when I was young to become a physician,” Dr. Isufi says.

    As she visits her cancer patients today, Dr. Isufi spends time getting to know each one so that she can provide reassurance for each person’s unique situation. “I tell them we are in this together and that I’ll do my best to help them get through it all—beginning to end,” she says. Dr. Isufi continues to check in on patients who have been in remission for many years after receiving their treatment.

    “My patients are very grateful, brave, and courageous, and this inspires me,” she says.

    Dr. Isufi is an assistant professor of hematology at Yale School of Medicine, where she also runs clinical trials in patients with lymphoma.

    Clinical Specialties

    Hematologic Oncology; Leukemia & Lymphoma; Hematology

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    Locations

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