2013
Altered vascular activation due to deficiency of the NADPH oxidase component p22phox
Wang H, Albadawi H, Siddiquee Z, Stone J, Panchenko M, Watkins M, Stone J. Altered vascular activation due to deficiency of the NADPH oxidase component p22phox. Cardiovascular Pathology 2013, 23: 35-42. PMID: 24035466, DOI: 10.1016/j.carpath.2013.08.003.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarotid Artery InjuriesCarotid Artery, CommonCase-Control StudiesCasein Kinase IalphaCells, CulturedCoronary VesselsCytochrome b GroupElastic TissueFemaleGranulomatous Disease, ChronicHeterogeneous-Nuclear Ribonucleoprotein Group CHumansHyperplasiaInfantMaleMatrix Metalloproteinase 12MiceMice, KnockoutMuscle, Smooth, VascularNADPH OxidasesNeointimaReactive Oxygen SpeciesRNA InterferenceTissue Inhibitor of Metalloproteinase-1TransfectionConceptsWild-type littermatesElastic fiber lossVascular activationDeficient miceIntimal hyperplasiaNADPH oxidase complexCoronary artery smooth muscle cellsNicotinamide adenine dinucleotide phosphate (NADPH) oxidaseArtery smooth muscle cellsHuman coronary artery smooth muscle cellsAdenine Dinucleotide Phosphate OxidaseBasal blood pressureCarotid artery ligationExpression ratioSmooth muscle cellsLung biopsyBlood pressureFiber lossArtery ligationCarotid ligationCarotid arteryTissue inhibitorHuman patientsMuscle cellsMice
2000
Hepatocyte Growth Factor Enhances MMP Activity in Human Endothelial Cells
Wang H, Keiser J. Hepatocyte Growth Factor Enhances MMP Activity in Human Endothelial Cells. Biochemical And Biophysical Research Communications 2000, 272: 900-905. PMID: 10860849, DOI: 10.1006/bbrc.2000.2852.Peer-Reviewed Original ResearchMeSH KeywordsCell LineCell MovementCollagenCoronary VesselsDermisDose-Response Relationship, DrugDrug CombinationsEndothelium, VascularEnzyme ActivationEnzyme InductionFlavonoidsHepatocyte Growth FactorHumansLamininMAP Kinase Signaling SystemMatrix Metalloproteinase 2Matrix Metalloproteinase InhibitorsMatrix Metalloproteinases, Membrane-AssociatedMetalloendopeptidasesMitogen-Activated Protein KinasesMolecular WeightPhosphorylationProteoglycansProto-Oncogene Proteins c-metRNA, MessengerConceptsSF/HGFHepatocyte growth factorExtracellular matrixMAP kinase cascadeSignal transduction pathwaysScatter factorMT1-MMP synthesisMatrix metalloproteinasesGrowth factorHuman EC linesKinase cascadeTransduction pathwaysEC invasionHGF stimulationEndothelial cell productionHuman endothelial cellsMMP-2 activationArterial ECsMT1-MMPVessel stabilizationTube formationCurrent studyAngiogenic factorsEC linesMMP activity