2021
Tumor suppressor p53 regulates intestinal type 2 immunity
Chang C, Wang J, Zhao Y, Liu J, Yang X, Yue X, Wang H, Zhou F, Inclan-Rico J, Ponessa J, Xie P, Zhang L, Siracusa M, Feng Z, Hu W. Tumor suppressor p53 regulates intestinal type 2 immunity. Nature Communications 2021, 12: 3371. PMID: 34099671, PMCID: PMC8184793, DOI: 10.1038/s41467-021-23587-x.Peer-Reviewed Original ResearchConceptsType 2 immunityRole of p53Parasitic infectionsInnate lymphoid cell responsesLymphoid cell responsesImmune integrityInfection of parasitesNippostrongylus brasiliensisTuft cellsCell responsesImmunityInfectionTritrichomonas murisTumor suppressor p53P53Unrecognized functionTumor suppressionSuppressor p53Critical triggerCritical roleCell circuitRoleResponse
2018
GalNAc-Specific Soybean Lectin Inhibits HIV Infection of Macrophages through Induction of Antiviral Factors
Zhou R, Wang X, Liu H, Guo L, Su Q, Wang H, Vasiliadis T, Ho W, Li J. GalNAc-Specific Soybean Lectin Inhibits HIV Infection of Macrophages through Induction of Antiviral Factors. Journal Of Virology 2018, 92: 10.1128/jvi.01720-17. PMID: 29263266, PMCID: PMC5827391, DOI: 10.1128/jvi.01720-17.Peer-Reviewed Original ResearchConceptsMannose-binding lectinHIV infectionT cellsInterferon-stimulated genesMitogenic effectAntiviral factorsHIV agentsAttachment of HIVAntiviral interferon-stimulated genesActivation of CD4Suppression of HIVDose-dependent fashionGlycosylated envelope proteinsAnti-HIV activityGroups of macrophagesC chemokinesCoreceptor CCR5HIV gp120HIV microbicidesBeta interferonHIVClinical settingCD4InfectionMacrophages
2017
IFN-λ Inhibits Drug-Resistant HIV Infection of Macrophages
Wang X, Wang H, Liu MQ, Li JL, Zhou RH, Zhou Y, Wang YZ, Zhou W, Ho WZ. IFN-λ Inhibits Drug-Resistant HIV Infection of Macrophages. Frontiers In Immunology 2017, 8: 210. PMID: 28321215, PMCID: PMC5337814, DOI: 10.3389/fimmu.2017.00210.Peer-Reviewed Original ResearchIFN-λsHIV infectionAZT-resistant virusResistant HIV InfectionAnti-HIV effectInhibitor-resistant virusesType III interferonsDrug-resistant strainsMyxovirus resistance 2III interferonsHIV activityInfected macrophagesTherapeutic agentsNumber of virusesMacrophagesInfectionInfected cellsRestriction factorsHIV releaseVirusResistance 2Cellular factorsAdditional evidenceAntiretroviralsHIV
2011
Tongue necrosis and systemic vascular amyloidosis
Lin J, Wang H, Collins A, Stone J. Tongue necrosis and systemic vascular amyloidosis. Human Pathology 2011, 42: 734-737. PMID: 21236468, DOI: 10.1016/j.humpath.2010.08.011.Peer-Reviewed Original Research