2016
Anterior Leaflet Augmentation With CorMatrix Porcine Extracellular Matrix in Twenty-Five Patients: Unexpected Patch Failures and Histologic Analysis
Kelley T, Kashem M, Wang H, McCarthy J, Carroll N, Moser G, Guy T. Anterior Leaflet Augmentation With CorMatrix Porcine Extracellular Matrix in Twenty-Five Patients: Unexpected Patch Failures and Histologic Analysis. The Annals Of Thoracic Surgery 2016, 103: 114-120. PMID: 27623276, DOI: 10.1016/j.athoracsur.2016.05.090.Peer-Reviewed Original ResearchConceptsAnterior leaflet augmentationSevere mitral regurgitationMitral regurgitationLeaflet augmentationLate deathsAutologous pericardiumECM patchPorcine extracellular matrixType of MRChronic obstructive pulmonary diseaseLower body mass indexFollow-up echocardiogramChronic renal failureObstructive pulmonary diseaseSubset of patientsVentricular ejection fractionBody mass indexSuture line dehiscenceResult of complicationsCorMatrix Extracellular MatrixTemple University HospitalDa Vinci surgical robotExtracellular matrixCause 7Chart review
2000
Hepatocyte Growth Factor Enhances MMP Activity in Human Endothelial Cells
Wang H, Keiser J. Hepatocyte Growth Factor Enhances MMP Activity in Human Endothelial Cells. Biochemical And Biophysical Research Communications 2000, 272: 900-905. PMID: 10860849, DOI: 10.1006/bbrc.2000.2852.Peer-Reviewed Original ResearchMeSH KeywordsCell LineCell MovementCollagenCoronary VesselsDermisDose-Response Relationship, DrugDrug CombinationsEndothelium, VascularEnzyme ActivationEnzyme InductionFlavonoidsHepatocyte Growth FactorHumansLamininMAP Kinase Signaling SystemMatrix Metalloproteinase 2Matrix Metalloproteinase InhibitorsMatrix Metalloproteinases, Membrane-AssociatedMetalloendopeptidasesMitogen-Activated Protein KinasesMolecular WeightPhosphorylationProteoglycansProto-Oncogene Proteins c-metRNA, MessengerConceptsSF/HGFHepatocyte growth factorExtracellular matrixMAP kinase cascadeSignal transduction pathwaysScatter factorMT1-MMP synthesisMatrix metalloproteinasesGrowth factorHuman EC linesKinase cascadeTransduction pathwaysEC invasionHGF stimulationEndothelial cell productionHuman endothelial cellsMMP-2 activationArterial ECsMT1-MMPVessel stabilizationTube formationCurrent studyAngiogenic factorsEC linesMMP activity