2018
Clinical implication of the new TNM classification of thymic malignancies
Detterbeck FC. Clinical implication of the new TNM classification of thymic malignancies. Journal Of Thoracic Disease 2018, 1: s2692-s2695. PMID: 30345107, PMCID: PMC6178297, DOI: 10.21037/jtd.2018.08.36.Peer-Reviewed Original Research
2017
Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database
Padda SK, Yao X, Antonicelli A, Riess JW, Shang Y, Shrager JB, Korst R, Detterbeck F, Huang J, Burt BM, Wakelee HA, Badve SS. Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database. Journal Of Thoracic Oncology 2017, 13: 436-446. PMID: 29191778, PMCID: PMC5983900, DOI: 10.1016/j.jtho.2017.11.118.Peer-Reviewed Original ResearchConceptsThymic epithelial tumorsIndependent prognostic factorOverall survivalPrognostic factorsPrognostic roleRetrospective databaseCox proportional hazards modelKaplan-Meier methodRecurrence-free survivalProportional hazards modelParaneoplastic syndromeCumulative incidenceResection statusTotal thymectomyMyasthenia gravisThymic malignanciesHistologic typeSyndrome statusFemale sexTreatment characteristicsEpithelial tumorsHazards modelLower CIRSyndromeMultivariate analysisPositron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
Korst RJ, Fernando S, Catlin AC, Rutledge JR, Girard N, Huang J, Detterbeck F, Database C. Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database. The Annals Of Thoracic Surgery 2017, 104: 1815-1820. PMID: 29033016, PMCID: PMC5785101, DOI: 10.1016/j.athoracsur.2017.06.053.Peer-Reviewed Original ResearchConceptsPositron emission tomographyInternational Thymic Malignancy Interest GroupHistologic typeThymic malignanciesPretreatment workupPathologic stageEmission tomographyProspective databaseThymic tumorsTumor stageMaximum standardized uptake valueProspective research databaseHistologic tumor typeThymic epithelial tumorsStandardized uptake valueCharacteristic curveAnalysis of receiverClinicopathologic featuresRare tumorEpithelial tumorsLarge cohortResearch DatabaseUptake valueTumor typesPatients
2016
Thymic Carcinoma Management Patterns among International Thymic Malignancy Interest Group (ITMIG) Physicians with Consensus from the Thymic Carcinoma Working Group
Shepherd A, Riely G, Detterbeck F, Simone CB, Ahmad U, Huang J, Korst R, Rajan A, Rimner A. Thymic Carcinoma Management Patterns among International Thymic Malignancy Interest Group (ITMIG) Physicians with Consensus from the Thymic Carcinoma Working Group. Journal Of Thoracic Oncology 2016, 12: 745-751. PMID: 27876674, PMCID: PMC5545114, DOI: 10.1016/j.jtho.2016.11.2219.Peer-Reviewed Original ResearchConceptsInternational Thymic Malignancy Interest GroupThymic carcinomaAreas of controversyResectable diseaseMultimodality therapyClinical practiceFirst-line chemotherapy regimenDefinitive surgical resectionRare epithelial malignancyManagement of patientsCurrent clinical practiceFit patientsAdjuvant therapyChemotherapy regimenSurgical resectionThymic malignanciesHistologic confirmationTreatment courseTreatment strategiesEpithelial malignanciesGreat vesselsMultidisciplinary discussionGroup physiciansWorking GroupCarcinomaThe impact of ChART on the science of thymic malignancies
Detterbeck F. The impact of ChART on the science of thymic malignancies. Journal Of Thoracic Disease 2016, 8: 1921. PMID: 27619638, PMCID: PMC4999693, DOI: 10.21037/jtd.2016.07.64.Peer-Reviewed Original Research
2014
Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors
Huang J, Ahmad U, Antonicelli A, Catlin AC, Fang W, Gomez D, Loehrer P, Lucchi M, Marom E, Nicholson A, Ruffini E, Travis W, Van Schil P, Wakelee H, Yao X, Detterbeck F, Committee and Contributors O. Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors. Journal Of Thoracic Oncology 2014, 9: 1573-1578. PMID: 25521402, DOI: 10.1097/jto.0000000000000269.Peer-Reviewed Original ResearchConceptsInternational Thymic Malignancy Interest GroupThymic carcinomaThymic carcinoidMedian overall survivalSingle-institution seriesOverall survivalThymic malignanciesMyasthenia gravisRare tumorHistologic classificationSex distributionThymomaCarcinoidsCarcinomaRetrospective dataType B2Rare groupTumorsPatientsMalignancyGreater proportionInternational databasesYearsGravisGroupThe ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the TNM Classification of Malignant Tumors
Bhora FY, Chen DJ, Detterbeck FC, Asamura H, Falkson C, Filosso PL, Giaccone G, Huang J, Kim J, Kondo K, Lucchi M, Marino M, Marom EM, Nicholson AG, Okumura M, Ruffini E, Van Schil P, Committee††† O, Boards‡‡‡ A. The ITMIG/IASLC Thymic Epithelial Tumors Staging Project: A Proposed Lymph Node Map for Thymic Epithelial Tumors in the Forthcoming 8th Edition of the TNM Classification of Malignant Tumors. Journal Of Thoracic Oncology 2014, 9: s88-s96. PMID: 25396317, DOI: 10.1097/jto.0000000000000293.Peer-Reviewed Original ResearchConceptsThymic malignanciesNodal diseaseNeck surgeryNode mapInternational Thymic Malignancy Interest GroupLymph node dissectionThymic epithelial tumorsLymph node mapPrior classification systemsPrognostic Factors CommitteeNode dissectionNodal involvementNode stagingTNM classificationLung cancerMalignant tumorsEpithelial tumorsOtolaryngology-HeadLymphatic drainageIASLC stagingAmerican AcademyMalignancyStagingAnatomical studyDiseaseThe IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors
Kondo K, Van Schil P, Detterbeck FC, Okumura M, Stratton K, Giroux D, Asamura H, Crowley J, Falkson C, Filosso PL, Giaccone G, Huang J, Kim J, Lucchi M, Marino M, Marom EM, Nicholson AG, Ruffini E, Committee††† O, Boards‡‡‡ M, Domain§§§ P. The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. Journal Of Thoracic Oncology 2014, 9: s81-s87. PMID: 25396316, DOI: 10.1097/jto.0000000000000291.Peer-Reviewed Original ResearchThe IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the T component for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors
Nicholson AG, Detterbeck FC, Marino M, Kim J, Stratton K, Giroux D, Asamura H, Crowley J, Falkson C, Filosso PL, Giaccone G, Huang J, Kondo K, Lucchi M, Marom EM, Okumura M, Ruffini E, Van Schil P, Committee††† O, Boards‡‡‡ M, Domain§§§ P. The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the T component for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. Journal Of Thoracic Oncology 2014, 9: s73-s80. PMID: 25396315, DOI: 10.1097/jto.0000000000000303.Peer-Reviewed Original ResearchConceptsAmerican Joint CommitteeCancer/UnionMalignant tumorsJoint CommitteeAnterior mediastinal fatIntrapericardial pulmonary arteriesMore central structuresThymic epithelial neoplasmsMetastasis classification systemSuperior vena cavaPrognostic Factors CommitteeThymic malignanciesArch vesselsPhrenic nervePulmonary arteryTNM classificationMetastasis classificationBrachiocephalic veinMediastinal pleuraT categoryVena cavaCapsular invasionLung cancerStage classificationMediastinal fatWhich Way is Up? Policies and Procedures for Surgeons and Pathologists Regarding Resection Specimens of Thymic Malignancy
Detterbeck FC, Moran C, Huang J, Suster S, Walsh G, Kaiser L, Wick M. Which Way is Up? Policies and Procedures for Surgeons and Pathologists Regarding Resection Specimens of Thymic Malignancy. Chinese Journal Of Lung Cancer 2014, 17: 95-103. PMID: 24581159, PMCID: PMC6131236, DOI: 10.3779/j.issn.1009-3419.2014.02.06.Peer-Reviewed Original ResearchThe International Thymic Malignancy Interest Group Thymic Initiative: A State-of-the-Art Study of Thymic Malignancies
Detterbeck F, Korst R. The International Thymic Malignancy Interest Group Thymic Initiative: A State-of-the-Art Study of Thymic Malignancies. Seminars In Thoracic And Cardiovascular Surgery 2014, 26: 317-322. PMID: 25837546, DOI: 10.1053/j.semtcvs.2015.02.002.Peer-Reviewed Original ResearchConceptsInternational Thymic Malignancy Interest GroupThymic malignanciesReporting of outcomesRare tumorLung cancer
2013
Thymoma: current diagnosis and treatment.
Detterbeck FC, Zeeshan A. Thymoma: current diagnosis and treatment. Chinese Medical Journal 2013, 126: 2186-91. PMID: 23769581, DOI: 10.3760/cma.j.issn.0366-6999.20130177.Peer-Reviewed Original ResearchConceptsComplete resectionInternational Thymic Malignancy Interest GroupMasaoka-Koga classificationMainstay of treatmentMajor prognostic factorAnterior mediastinal tumorTreatment of thymomaEarly-stage thymomaRare malignant tumorCore needle biopsyStandard diagnostic modalityFine-needle aspirationFormal systematic reviewMajor blood vesselsIVA tumorsPreoperative chemotherapyPrimary surgeryPostoperative radiationPrognostic factorsSurgical resectionThymic malignanciesMediastinal tumorMyasthenia gravisThymoma resectionIntravenous contrast
2011
Standard Outcome Measures for Thymic Malignancies
Huang J, Detterbeck FC, Wang Z, Loehrer PJ. Standard Outcome Measures for Thymic Malignancies. Journal Of Thoracic Oncology 2011, 6: s1691-s1697. PMID: 21847049, DOI: 10.1097/jto.0b013e3182254ac1.Peer-Reviewed Original ResearchWhich Way is Up? Policies and Procedures for Surgeons and Pathologists Regarding Resection Specimens of Thymic Malignancy
Detterbeck FC, Moran C, Huang J, Suster S, Walsh G, Kaiser L, Wick M. Which Way is Up? Policies and Procedures for Surgeons and Pathologists Regarding Resection Specimens of Thymic Malignancy. Journal Of Thoracic Oncology 2011, 6: s1730-s1738. PMID: 21847055, DOI: 10.1097/jto.0b013e31821ea567.Peer-Reviewed Original ResearchManagement of Thymic Tumors: A Survey of Current Practice among Members of the European Society of Thoracic Surgeons
Ruffini E, Van Raemdonck D, Detterbeck F, Rocco G, Thomas P, Venuta F, Group T. Management of Thymic Tumors: A Survey of Current Practice among Members of the European Society of Thoracic Surgeons. Journal Of Thoracic Oncology 2011, 6: 614-623. PMID: 21266921, DOI: 10.1097/jto.0b013e318207cd74.Peer-Reviewed Original ResearchConceptsThymic tumorsPreoperative assessmentTomography scanThoracic surgeonsPositron emission tomography scanWorld Health Organization classificationRole of surgeryStage IVA thymomaEuropean SocietyEmission tomography scanManagement of thymomasESTS membersReliable staging systemType C thymomasAreas of controversyIVA thymomaExtrapleural pneumonectomyExtended resectionRecurrent diseasePostoperative treatmentThymic malignanciesHistologic confirmationStaging systemOrganization classificationObservational study
2010
Standard Outcome Measures for Thymic Malignancies
Huang J, Detterbeck FC, Wang Z, Loehrer PJ. Standard Outcome Measures for Thymic Malignancies. Journal Of Thoracic Oncology 2010, 5: 2017-2023. PMID: 20978450, DOI: 10.1097/jto.0b013e3181f13682.Peer-Reviewed Original Research