2014
Impact of Adjuvant Treatment for Microscopic Residual Disease After Non-Small Cell Lung Cancer Surgery
Hancock JG, Rosen JE, Antonicelli A, Moreno A, Kim AW, Detterbeck FC, Boffa DJ. Impact of Adjuvant Treatment for Microscopic Residual Disease After Non-Small Cell Lung Cancer Surgery. The Annals Of Thoracic Surgery 2014, 99: 406-413. PMID: 25528723, DOI: 10.1016/j.athoracsur.2014.09.033.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerPositive surgical marginsCell lung cancerSurgical marginsR1 resectionNSCLC patientsResidual diseaseLung cancerNational Cancer Data BasePathologic stage IMicroscopic residual diseaseAdministration of chemotherapyOptimal treatment approachStage pIR1 patientsAdjuvant treatmentPostoperative administrationAdjuvant approachIncomplete resectionPostoperative radiationComplete resectionImproved survivalPI patientsPositive marginsSuperior survival
2004
Bronchial margins in lung cancer resection specimens: utility of frozen section and gross evaluation
Maygarden SJ, Detterbeck FC, Funkhouser WK. Bronchial margins in lung cancer resection specimens: utility of frozen section and gross evaluation. Modern Pathology 2004, 17: 1080-1086. PMID: 15133477, DOI: 10.1038/modpathol.3800154.Peer-Reviewed Original ResearchConceptsPositive marginsSite of tumorBronchial marginGross tumorFrozen sectionsWedge resectionCell carcinomaGross evaluationSalivary gland-type tumorsCentral lung tumorsPositive margin casesLung cancer resectionNonsmall cell carcinomaFrozen section evaluationSmall cell carcinomaFalse-negative casesTrue positive casesCancer resectionMucosal tumorsMargin positivityNegative marginsIntramucosal carcinomaTumor distanceUNC HospitalsLung tumors