2006
Clinical features associated to refractory obsessive–compulsive disorder
Ferrão Y, Shavitt R, Bedin N, de Mathis M, Lopes A, Fontenelle L, Torres A, Miguel E. Clinical features associated to refractory obsessive–compulsive disorder. Journal Of Affective Disorders 2006, 94: 199-209. PMID: 16764938, DOI: 10.1016/j.jad.2006.04.019.Peer-Reviewed Original ResearchAdultBrazilCase-Control StudiesChronic DiseaseCodependency, PsychologicalCognitive Behavioral TherapyCombined Modality TherapyComorbidityElectroconvulsive TherapyFemaleHospitalizationHumansMaleMental DisordersMiddle AgedObsessive-Compulsive DisorderQuality of LifeSelective Serotonin Reuptake InhibitorsSocioeconomic FactorsTreatment Failure
2005
A family study of early‐onset obsessive‐compulsive disorder
do Rosario‐Campos M, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early‐onset obsessive‐compulsive disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2005, 136B: 92-97. PMID: 15892140, DOI: 10.1002/ajmg.b.30149.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRecurrence riskChronic ticsFirst-degree family membersChildhood-onset obsessive-compulsive disorderDiagnosis of OCDChronic tic disorderStandardized semi-structured interviewFirst-degree relativesEarly-onset casesOnset obsessive-compulsive disorderDSM-IV criteriaEarly-onset obsessive-compulsive disorderBest-estimate processRandom digit dialingHigh comorbid ratesAge of onsetFamily studiesHigh genetic loadingMean ageSpecialty clinicTic disordersComorbid ratesValid subgroupsCase relativesCitalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder
Fontenelle L, Mendlowicz M, Miguel E, Versiani M. Citalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder. The World Journal Of Biological Psychiatry 2005, 6: 57-59. PMID: 16097406, DOI: 10.1080/15622970510029740.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderObsessive-compulsive disorderSRI-resistant obsessive compulsive disorderResistant obsessive-compulsive disorderCombination of citalopramFirst-line treatmentAdequate trialReuptake inhibitorsCompulsive disorderPatientsCitalopramDisordersFuture studiesTrials