2017
Long‐term outcomes of Group D retinoblastoma eyes during the intravitreal melphalan era
Berry JL, Shah S, Bechtold M, Zolfaghari E, Jubran R, Kim JW. Long‐term outcomes of Group D retinoblastoma eyes during the intravitreal melphalan era. Pediatric Blood & Cancer 2017, 64 PMID: 28646513, DOI: 10.1002/pbc.26696.Peer-Reviewed Original ResearchConceptsGroup D eyesGroup D retinoblastoma eyesD eyesSystemic chemoreductionIntravitreal melphalanSalvage rateRetinoblastoma eyesIntravitreal melphalan injectionRetrospective chart reviewOverall salvage ratePrimary outcome measurementLong-term outcomesExternal beam radiationOcular salvageSalvage therapyVitreous seedsChart reviewGlobe salvageIntravitreal injectionKaplan-MeierTreatment modalitiesTumor recurrenceMelphalan injectionOutcome measurementsMelphalanNot All Seeds Are Created Equal: Seed Classification Is Predictive of Outcomes in Retinoblastoma
Berry JL, Bechtold M, Shah S, Zolfaghari E, Reid M, Jubran R, Kim JW. Not All Seeds Are Created Equal: Seed Classification Is Predictive of Outcomes in Retinoblastoma. Ophthalmology 2017, 124: 1817-1825. PMID: 28655537, DOI: 10.1016/j.ophtha.2017.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, AlkylatingAntineoplastic Combined Chemotherapy ProtocolsCarboplatinChildChild, PreschoolCryotherapyEtoposideFemaleFollow-Up StudiesHumansInfantInfusions, IntravenousIntravitreal InjectionsLaser CoagulationMaleMelphalanNeoplasm SeedingRetinal NeoplasmsRetinoblastomaRetrospective StudiesSalvage TherapyVincristineVitreous BodyConceptsIntra-arterial chemotherapyIntravitreal melphalanIntravenous chemotherapyVitreous seedingSalvage rateRetrospective reviewIVM injectionsOverall globe salvage ratePrimary intra-arterial chemotherapyGlobe salvage rateNonrandomized retrospective reviewOutcome of retinoblastomaRecurrent vitreous seedingPrimary outcome measureActive retinoblastomaVitreous seedsGlobe salvageIntravitreal chemotherapySingle centerIntravitreal injectionMore injectionsGrade 3Outcome measuresSecondary measuresEffective treatment
2016
Risk of metastasis and orbital recurrence in advanced retinoblastoma eyes treated with systemic chemoreduction versus primary enucleation
Berry JL, Kogachi K, Aziz HA, McGovern K, Zolfaghari E, Murphree AL, Jubran R, Kim JW. Risk of metastasis and orbital recurrence in advanced retinoblastoma eyes treated with systemic chemoreduction versus primary enucleation. Pediatric Blood & Cancer 2016, 64: e26270. PMID: 28221729, PMCID: PMC7034314, DOI: 10.1002/pbc.26270.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsCarboplatinCombined Modality TherapyEtoposideEye EnucleationFemaleFollow-Up StudiesHumansInfantMaleNeoplasm Recurrence, LocalNeoplasm StagingOrbital NeoplasmsPrognosisRetinal NeoplasmsRetinoblastomaRetrospective StudiesRisk FactorsSalvage TherapyVincristineConceptsPrimary enucleation groupSystemic chemoreductionHigh-risk pathologyMetastatic diseaseOrbital recurrencePrimary enucleationAdvanced retinoblastomaEnucleation groupTreatment failureHigh-risk pathologic featuresChildren's Hospital Los AngelesPrimary outcome measureRisk of metastasisSalvage therapySecondary enucleationRetrospective reviewE retinoblastomaMedian timePathologic featuresRetinoblastoma eyesTreatment modalitiesPoor responseOutcome measuresChemoreductionSubsequent enucleation